Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Ulrike Kuckelkorn"'
Autor:
Izabela Mlynarczuk-Bialy, Thorsten R. Doeppner, Jakub Golab, Dominika Nowis, Grzegorz M. Wilczynski, Kamil Parobczak, Moritz E. Wigand, Malgorzata Hajdamowicz, Łukasz P. Biały, Olga Aniolek, Petra Henklein, Mathias Bähr, Boris Schmidt, Ulrike Kuckelkorn, Peter-M. Kloetzel
Publikováno v:
Translational Oncology, Vol 7, Iss 5, Pp 570-579 (2014)
Inhibition of the proteasome offers many therapeutic possibilities in inflammation as well as in neoplastic diseases. However, clinical use of proteasome inhibitors is limited by the development of resistance or severe side effects. In our study we c
Externí odkaz:
https://doaj.org/article/dac0949447534c1b883208e645e9afcb
Autor:
Ricardo Camargo, Liliam O Faria, Alexander Kloss, Cecília B F Favali, Ulrike Kuckelkorn, Peter-Michael Kloetzel, Cezar Martins de Sá, Beatriz D Lima
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95977 (2014)
Generally, Trypanosoma cruzi infection in human is persistent and tends to chronicity, suggesting that the parasite evade the immune surveillance by down regulating the intracellular antigen processing routes. Within the MHC class I pathway, the majo
Externí odkaz:
https://doaj.org/article/501a6b8aba65450ea39d9a454900fdd9
Autor:
Thorsten Joeris, Nicole Schmidt, David Ermert, Petra Krienke, Alexander Visekruna, Ulrike Kuckelkorn, Stefan H E Kaufmann, Ulrich Steinhoff
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39827 (2012)
Proteasomes are the major enzyme complexes for non-lysosomal protein degradation in eukaryotic cells. Mammals express two sets of catalytic subunits: the constitutive subunits β1, β2 and β5 and the immunosubunits LMP2 (β1i), MECL-1 (β2i) and LMP
Externí odkaz:
https://doaj.org/article/b2316f1d976c41eda4efbc2326203c57
Autor:
Elisa Opitz, Annett Koch, Karin Klingel, Frank Schmidt, Stefan Prokop, Anna Rahnefeld, Martina Sauter, Frank L Heppner, Uwe Völker, Reinhard Kandolf, Ulrike Kuckelkorn, Karl Stangl, Elke Krüger, Peter M Kloetzel, Antje Voigt
Publikováno v:
PLoS Pathogens, Vol 7, Iss 9, p e1002233 (2011)
Proteasomes recognize and degrade poly-ubiquitinylated proteins. In infectious disease, cells activated by interferons (IFNs) express three unique catalytic subunits β1i/LMP2, β2i/MECL-1 and β5i/LMP7 forming an alternative proteasome isoform, the
Externí odkaz:
https://doaj.org/article/d2dbeb93a01945528f41de1fbc1d9375
Autor:
Ulrike Seifert, Peter-M. Kloetzel, Dirk Schadendorf, Christian Hagemeier, Lüder Wiebusch, Christina Montag, Antje Ludwig, Jakub Gołąb, Sumaira Umbreen, Boris Schmidt, Ulrike Kuckelkorn, Heike Roeckmann, Izabela Młynarczuk-Biały
Resistance of tumor cells to cisplatin is a common feature frequently encountered during chemotherapy against melanoma caused by various known and unknown mechanisms. To overcome drug resistance toward cisplatin, a targeted treatment using alternativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b8396d7d26ced9635c307c1813bb60
https://doi.org/10.1158/0008-5472.c.6494339
https://doi.org/10.1158/0008-5472.c.6494339
Autor:
Ulrike Seifert, Peter-M. Kloetzel, Dirk Schadendorf, Christian Hagemeier, Lüder Wiebusch, Christina Montag, Antje Ludwig, Jakub Gołąb, Sumaira Umbreen, Boris Schmidt, Ulrike Kuckelkorn, Heike Roeckmann, Izabela Młynarczuk-Biały
Supplementary Figure 2 from Combined Effect of Proteasome and Calpain Inhibition on Cisplatin-Resistant Human Melanoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304e50c0af32bd943d1c72942153ffb9
https://doi.org/10.1158/0008-5472.22364750
https://doi.org/10.1158/0008-5472.22364750
Autor:
Ulrike Seifert, Peter-M. Kloetzel, Dirk Schadendorf, Christian Hagemeier, Lüder Wiebusch, Christina Montag, Antje Ludwig, Jakub Gołąb, Sumaira Umbreen, Boris Schmidt, Ulrike Kuckelkorn, Heike Roeckmann, Izabela Młynarczuk-Biały
Supplementary Figure 1 from Combined Effect of Proteasome and Calpain Inhibition on Cisplatin-Resistant Human Melanoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029928b8579bb9a077d7ccbe5ebde5fa
https://doi.org/10.1158/0008-5472.22364753.v1
https://doi.org/10.1158/0008-5472.22364753.v1
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1988
Mass spectrometry (MS) is today one of the most important analytical techniques in biosciences. The development of electro spray ionization (ESI) as a gentle method, in which molecules are not destroyed, has revolutionized the analytic of peptides. M
Autor:
Katharina Janek, Sabine Stübler, Juliane Liepe, Michael P. H. Stumpf, Ulrike Kuckelkorn, Kathrin Textoris-Taube, Petra Henklein, Agathe Niewienda, Michele Mishto, Christiane Kilian
Publikováno v:
Journal of Biological Chemistry
Kuckelkorn, U, Stübler, S, Textoris-Taube, K, Killian, C, Niewienda, A, Henklein, P, Janek, K, Stumpf, M P, Mishto, M & Liepe, J 2019, ' Proteolytic dynamics of human 20S thymoproteasome ', Journal of Biological Chemistry, vol. 294, no. 19, pp. 7740-7754 . https://doi.org/10.1074/jbc.RA118.007347
J Biol Chem
Kuckelkorn, U, Stübler, S, Textoris-Taube, K, Killian, C, Niewienda, A, Henklein, P, Janek, K, Stumpf, M P, Mishto, M & Liepe, J 2019, ' Proteolytic dynamics of human 20S thymoproteasome ', Journal of Biological Chemistry, vol. 294, no. 19, pp. 7740-7754 . https://doi.org/10.1074/jbc.RA118.007347
J Biol Chem
An efficient immunosurveillance of CD8+ T cells in the periphery depends on positive/negative selection of thymocytes and thus on the dynamics of antigen degradation and epitope production by thymoproteasome and immunoproteasome in the thymus. Althou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebcdee0ccd9b70a79bab4a0839d028a3
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/49390
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/49390
Publikováno v:
Antigen Processing ISBN: 9781493994496
Mass spectrometry (MS) is today one of the most important analytical techniques in biosciences. The development of electro spray ionization (ESI) as a gentle method, in which molecules are not destroyed, has revolutionized the analytic of peptides. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71255b62ee40c12b1b440a7bc22eba7d
https://doi.org/10.1007/978-1-4939-9450-2_2
https://doi.org/10.1007/978-1-4939-9450-2_2