Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ulrike Koitzsch"'
Autor:
Joelle Noriko Galang, Yefeng Shen, Ulrike Koitzsch, Xiaojie Yu, Hannah Eischeid-Scholz, Daniel Bachurski, Tilman T. Rau, Christina Neppl, Marco Herling, Bianca Bulimaga, Elena Vasyutina, Michal R. Schweiger, Reinhard Büttner, Margarete Odenthal, Maria M. Anokhina
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13981 (2023)
Lysine-specific demethylase 1 (LSD1) is highly expressed in many cancer types and strongly associated with cancer progression and metastasis. Circular RNAs (circRNAs) are produced by back-splicing and influence the interactive RNA network by microRNA
Externí odkaz:
https://doaj.org/article/cfb1dfa8d7dc4e1394482e1ade878ef4
Autor:
Xiaojie Yu, Natalia Elfimova, Marion Müller, Daniel Bachurski, Ulrike Koitzsch, Uta Drebber, Esther Mahabir, Hinrich P. Hansen, Scott L. Friedman, Sabine Klein, Hans Peter Dienes, Marianna Hösel, Reinhard Buettner, Jonel Trebicka, Vangelis Kondylis, Inge Mannaerts, Margarete Odenthal
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 6, Pp 1701-1716 (2022)
Background & Aims: Liver fibrosis arises from long-term chronic liver injury, accompanied by an accelerated wound healing response with interstitial accumulation of extracellular matrix (ECM). Activated hepatic stellate cells (HSC) are the main sourc
Externí odkaz:
https://doaj.org/article/4c80ebac8aa7408c99ac2c230a18d43f
Autor:
Claudia Vollbrecht, Fabian Dominik Mairinger, Ulrike Koitzsch, Martin Peifer, Katharina Koenig, Lukas Carl Heukamp, Giuliano Crispatzu, Laura Wilden, Karl-Anton Kreuzer, Michael Hallek, Margarete Odenthal, Carmen Diana Herling, Reinhard Buettner
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129544 (2015)
High resolution molecular studies have demonstrated that the clonal acquisition of gene mutations is an important mechanism that may promote rapid disease progression and drug resistance in chronic lymphocytic leukemia (CLL). Therefore, the early and
Externí odkaz:
https://doaj.org/article/6ad8741900c44a7e8f5cabb35c431fb3
Autor:
Tim Nestler, Priya Dalvi, Friederike Haidl, Maike Wittersheim, Melanie von Brandenstein, Pia Paffenholz, Svenja Wagener-Ryczek, David Pfister, Ulrike Koitzsch, Martin Hellmich, Reinhard Buettner, Margarete Odenthal, Axel Heidenreich
Publikováno v:
British Journal of Cancer. 126:937-947
Background Testicular germ cell tumours (TGCTs) have a high metastasis rate. However, the mechanisms related to their invasion, progression and metastasis are unclear. Therefore, we investigated gene expression changes that might be linked to metasta
Autor:
Xiaojie Yu, Natalia Elfimova, Marion Müller, Daniel Bachurski, Ulrike Koitzsch, Uta Drebber, Esther Mahabir, Hinrich P. Hansen, Scott L. Friedman, Sabine Klein, Hans Peter Dienes, Marianna Hösel, Reinhard Buettner, Jonel Trebicka, Vangelis Kondylis, Inge Mannaerts, Margarete Odenthal
Publikováno v:
cmgh
BACKGROUND & AIMS: Liver fibrosis arises from long-term chronic liver injury, accompanied by an accelerated wound healing response with interstitial accumulation of extracellular matrix (ECM). Activated hepatic stellate cells (HSC) are the main sourc
Autor:
Margarete Odenthal, Leonie Strake, Ulrike Koitzsch, Fabinshy Thangarajah, Lisa Richters, Verena Kirn, Jochen W.U. Fries, Hannah Eischeid
Publikováno v:
Clinical & Experimental Metastasis. 35:707-712
The role of ESR1 methylation in breast cancer and its influence on disease progression is not yet fully understood. Healthy breast tissue usually does not show ESR1 promoter methylation, whereas the frequency of ESR1 methylation appears to increase i
Autor:
Alexander Adam, Stephan C. Schaefer, Jeannine Meinrath, Hannah Eischeid, Jia Huang, Wafa Amer, Reinhard Buettner, Ulrike Koitzsch, Margarete Odenthal, Erik Vassella, Andreas H. Scheel, Anne Arens, Csaba D. Tóth
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Scientific Reports
Amer, Wafa; Toth, Csaba; Vassella, Erik; Meinrath, Jeannine; Koitzsch, Ulrike; Arens, Anne; Huang, Jia; Eischeid, Hannah; Adam, Alexander; Buettner, Reinhard; Scheel, Andreas; Schaefer, Stephan C; Odenthal, Margarete (2017). Evolution analysis of heterogeneous non-small cell lung carcinoma by ultra-deep sequencing of the mitochondrial genome. Scientific Reports, 7(1), p. 11069. Nature Publishing Group 10.1038/s41598-017-11345-3
Scientific Reports
Amer, Wafa; Toth, Csaba; Vassella, Erik; Meinrath, Jeannine; Koitzsch, Ulrike; Arens, Anne; Huang, Jia; Eischeid, Hannah; Adam, Alexander; Buettner, Reinhard; Scheel, Andreas; Schaefer, Stephan C; Odenthal, Margarete (2017). Evolution analysis of heterogeneous non-small cell lung carcinoma by ultra-deep sequencing of the mitochondrial genome. Scientific Reports, 7(1), p. 11069. Nature Publishing Group 10.1038/s41598-017-11345-3
Accurate assessment of tumour heterogeneity is an important issue that influences prognosis and therapeutic decision in molecular pathology. Due to the shortage of protective histones and a limited DNA repair capacity, the mitochondrial (mt)-genome u
Autor:
Nicolaus Friedrichs, Michael Kloth, Lukas C. Heukamp, Martin Peifer, Peter Propping, Ulrike Koitzsch, Markus Loeffler, Erika Mariotti, Alexandra Florin, Claudia Wodtke, Stefan Aretz, Sabine Merkelbach-Bruse, Christoph Engel, Reinhard Buettner, Katharina Koenig, Helen Kuenstlinger, Ursula Rommerscheidt-Fuss, Stefanie Holzapfel, Frank Ueckeroth, Thomas Zander, Vanessa Ruesseler, Margarete Odenthal
Publikováno v:
Gut. 65:1296-1305
Objective Microsatellite instability (MSI) is detected in approximately 15% of all colorectal cancers (CRC) and virtually in all cases with Lynch syndrome. The MSI phenotype is caused by dysfunctional mismatch repair (MMR) and leads to accumulation o
Autor:
Jana Fassunke, Janine Altmueller, Katharina Koenig, Peter Nuernberg, Reinhard Buettner, Sebastian Huss, Sabine Merkelbach-Bruse, Ulrike Koitzsch, Margarete Odenthal, Kerstin Becker, Claudia Vollbrecht, Lukas C. Heukamp
Publikováno v:
Journal of Clinical Pathology. 66:803-806
Due to the advanced progress in personalised therapy concepts for non-small cell lung cancer (NSCLC), we applied the ion semiconductor sequencing (ISS) approach to molecular diagnosis of NSCLC, analysing a set of therapy relevant gene loci. DNA from
Autor:
Helen Künstlinger, Alexander Quaas, Sabine Merkelbach-Bruse, Elfriede Bollschweiler, Peter P. Grimminger, Jeannine Meinrath, Maike Michalk, Michael Kloth, Arnulf H. Hölscher, Uta Drebber, Ulrike Koitzsch, Margarete Odenthal, Wolfgang Hartmann
Publikováno v:
Oncology reports. 35(4)
Esophageal cancer (EC) is one of the most common malignancies diagnosed in the Western world with an increasing incidence noted for esophageal adenocarcinoma (EAC). Despite improvements in staging, surgical procedures and postoperative treatments, th