Tolerance to Haemophilus influenzae infection in human epithelial cells: Insights from a primary cell-based model.

Autor: Ulrike Kappler, Anna Henningham, Marufa Nasreen, Ayaho Yamamoto, Andrew H Buultjens, Timothy P Stinear, Peter Sly, Emmanuelle Fantino

Publikováno v: PLoS Pathogens, Vol 20, Iss 7, p e1012282 (2024)

Haemophilus influenzae is a human respiratory pathogen and inhabits the human respiratory tract as its only niche. Despite this, the molecular mechanisms that allow H. influenzae to establish persistent infections of human epithelia are not well unde

Externí odkaz: https://doaj.org/article/44c07900fcf6437ea3f10fe629ba5f24

Combined functional genomic and metabolomic approaches identify new genes required for growth in human urine by multidrug-resistant Escherichia coli ST131

Autor: Minh-Duy Phan, Horst Joachim Schirra, Nguyen Thi Khanh Nhu, Kate M. Peters, Sohinee Sarkar, Luke P. Allsopp, Maud E. S. Achard, Ulrike Kappler, Mark A. Schembri

Publikováno v: mBio, Vol 15, Iss 3 (2024)

ABSTRACT Urinary tract infections (UTIs) are one of the most common bacterial infections in humans, with ~400 million cases across the globe each year. Uropathogenic Escherichia coli (UPEC) is the major cause of UTI and increasingly associated with a

Externí odkaz: https://doaj.org/article/a687fc2675674903803964d0b2c45e8d

Structural Basis for the Subversion of MAP Kinase Signaling by an Intrinsically Disordered Parasite Secreted Agonist

Autor: Mohamed-Ali Hakimi, Hassan Belrhali, Erika Pellegrini, Ulrike Kapp, Matthew W. Bowler, Andrés Palencia, Laurence Braun, Alexandre Bougdour

Publikováno v: Structure(London, England:1993)
Structure (London, England : 1993)
Structure (London, England : 1993), 2017, 25 (1), pp.16-26. ⟨10.1016/j.str.2016.10.011⟩
'Structure ', vol: 25, pages: 16-26 (2017)

Summary The causative agent of toxoplasmosis, the intracellular parasite Toxoplasma gondii, delivers a protein, GRA24, into the cells it infects that interacts with the mitogen-activated protein (MAP) kinase p38α (MAPK14), leading to activation and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0548b32a0f80d776db4bbfcbec030ddd
https://doi.org/10.1016/j.str.2016.10.011

Influence of Ultrasound on Embossing Results for Cardboard

Autor: Jennes Hunniger, Lutz Engisch, Simon Hamblyn, Ulrike Kappeler, André Hofmann

Publikováno v: BioResources, Vol 17, Iss 4, Pp 5803-5819 (2022)

The requirements for embossing of cardboard for print and packaging applications are constantly increasing. High degrees of forming, richness of detail, and high shape accuracy are desired. However, current embossing technology can only fulfil these

Externí odkaz: https://doaj.org/article/6295dcc9621041ccb18b27080ccd4ec3

Architecture of a Dodecameric Bacterial Replicative Helicase

Autor: Ulrike Kapp, Meike Stelter, Alexandre Bazin, Marc Jamin, Goran Bajic, Gael Goret, Laurent Terradot, Irina Gutsche, Joanna Timmins

Publikováno v: Structure
Structure, 2012, 20 (3), pp.554-64. ⟨10.1016/j.str.2012.01.020⟩
Structure, Elsevier (Cell Press), 2012, 20 (3), pp.554-64. ⟨10.1016/j.str.2012.01.020⟩
Stelter, M, Gutsche, I, Kapp, U, Bazin, A, Bajic, G, Goret, G, Jamin, M, Timmins, J & Terradot, L 2012, ' Architecture of a dodecameric bacterial replicative helicase ', Structure, vol. 20, no. 3, pp. 554-64 . https://doi.org/10.1016/j.str.2012.01.020

International audience; Hexameric DnaB helicases are often loaded at DNA replication forks by interacting with the initiator protein DnaA and/or a helicase loader (DnaC in Escherichia coli). These loaders are not universally required, and DnaB from H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92c6d2e6ec8d02fb41983ccca06ae8d