Structural Basis for the Subversion of MAP Kinase Signaling by an Intrinsically Disordered Parasite Secreted Agonist

Autor: Mohamed-Ali Hakimi, Hassan Belrhali, Erika Pellegrini, Ulrike Kapp, Matthew W. Bowler, Andrés Palencia, Laurence Braun, Alexandre Bougdour

Publikováno v: Structure(London, England:1993)
Structure (London, England : 1993)
Structure (London, England : 1993), 2017, 25 (1), pp.16-26. ⟨10.1016/j.str.2016.10.011⟩
'Structure ', vol: 25, pages: 16-26 (2017)

Summary The causative agent of toxoplasmosis, the intracellular parasite Toxoplasma gondii, delivers a protein, GRA24, into the cells it infects that interacts with the mitogen-activated protein (MAP) kinase p38α (MAPK14), leading to activation and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0548b32a0f80d776db4bbfcbec030ddd
https://doi.org/10.1016/j.str.2016.10.011

Architecture of a Dodecameric Bacterial Replicative Helicase

Autor: Ulrike Kapp, Meike Stelter, Alexandre Bazin, Marc Jamin, Goran Bajic, Gael Goret, Laurent Terradot, Irina Gutsche, Joanna Timmins

Publikováno v: Structure
Structure, 2012, 20 (3), pp.554-64. ⟨10.1016/j.str.2012.01.020⟩
Structure, Elsevier (Cell Press), 2012, 20 (3), pp.554-64. ⟨10.1016/j.str.2012.01.020⟩
Stelter, M, Gutsche, I, Kapp, U, Bazin, A, Bajic, G, Goret, G, Jamin, M, Timmins, J & Terradot, L 2012, ' Architecture of a dodecameric bacterial replicative helicase ', Structure, vol. 20, no. 3, pp. 554-64 . https://doi.org/10.1016/j.str.2012.01.020

International audience; Hexameric DnaB helicases are often loaded at DNA replication forks by interacting with the initiator protein DnaA and/or a helicase loader (DnaC in Escherichia coli). These loaders are not universally required, and DnaB from H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92c6d2e6ec8d02fb41983ccca06ae8d

Neanderthal adenylosuccinate lyase: insights in catalysis and link with disease-causing mutation

Autor: Kaja Ewa Moczulska, Bart Van Laer, Ulrike Kapp, Svante Pääbo, Gordon A. Leonard, Christoph Mueller-Dieckmann, Montserrat Soler-López

Publikováno v: Acta Crystallographica Section A Foundations and Advances. 74:e223-e223

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9da9cbe9fd4226b407fe5d210acd87fa
https://doi.org/10.1107/s2053273318091817

Structural Basis of the Nickel Response in Helicobacter pylori: Crystal Structures of HpNikR in Apo and Nickel-bound States

Autor: Cyril Dian, Agnès Labigne, Kristine Schauer, Laurent Terradot, Ulrike Kapp, Sean McSweeney

Publikováno v: Journal of Molecular Biology. 361:715-730

The survival of Helicobacter pylori in the human stomach critically relies on the availability and use of nickel, an absolute cofactor of the important virulence determinant urease. Nickel-responsive gene regulation is mediated by HpNikR, a protein b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e9731345bc6b40a36ccc78310c04ed
https://doi.org/10.1016/j.jmb.2006.06.058

The Structure of the Organic Hydroperoxide Resistance Protein from Deinococcus radiodurans

Autor: Sean McSweeney, Gordon A. Leonard, Ulrike Kapp, Cécile Meunier-Jamin

Publikováno v: Journal of Biological Chemistry. 279:25830-25837

The three-dimensional structure of the organic hydroperoxide resistance protein (OHRP) from Deinococcus radiodurans as determined using single crystal xray diffraction techniques is reported. Comparison of the structure with that obtained for OHRP fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ef3e4ae06d1cdff70a4fefefecf76a02
https://doi.org/10.1074/jbc.m312983200