Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Ulrike Heberlein"'
Autor:
Julia Ryvkin, Liora Omesi, Yong-Kyu Kim, Mali Levi, Hadar Pozeilov, Lital Barak-Buchris, Bella Agranovich, Ifat Abramovich, Eyal Gottlieb, Avi Jacob, Dick R. Nässel, Ulrike Heberlein, Galit Shohat-Ophir
Publikováno v:
PLoS Genetics, Vol 20, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/87960334a9674283b569ce4f24a9756f
Publikováno v:
BMC Biology, Vol 17, Iss 1, Pp 1-19 (2019)
Abstract Background Epigenetic mechanisms play fundamental roles in brain function and behavior and stressors such as social isolation can alter animal behavior via epigenetic mechanisms. However, due to cellular heterogeneity, identifying cell-type-
Externí odkaz:
https://doaj.org/article/f25228cbf7c4407e9747428de50a4d9d
Publikováno v:
Disease Models & Mechanisms, Vol 4, Iss 3, Pp 335-346 (2011)
SUMMARY Prenatal exposure to ethanol in humans results in a wide range of developmental abnormalities, including growth deficiency, developmental delay, reduced brain size, permanent neurobehavioral abnormalities and fetal death. Here we describe the
Externí odkaz:
https://doaj.org/article/f4cc9777ce494ce58f193d402f876047
Autor:
Yoshinori Aso, Divya Sitaraman, Toshiharu Ichinose, Karla R Kaun, Katrin Vogt, Ghislain Belliart-Guérin, Pierre-Yves Plaçais, Alice A Robie, Nobuhiro Yamagata, Christopher Schnaitmann, William J Rowell, Rebecca M Johnston, Teri-T B Ngo, Nan Chen, Wyatt Korff, Michael N Nitabach, Ulrike Heberlein, Thomas Preat, Kristin M Branson, Hiromu Tanimoto, Gerald M Rubin
Publikováno v:
eLife, Vol 3 (2014)
Animals discriminate stimuli, learn their predictive value and use this knowledge to modify their behavior. In Drosophila, the mushroom body (MB) plays a key role in these processes. Sensory stimuli are sparsely represented by ∼2000 Kenyon cells, w
Externí odkaz:
https://doaj.org/article/80cc4fc89fc9426e8ebf8f85444746e7
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87714 (2014)
Epidermal Growth Factor Receptor (EGFR) signaling has a conserved role in ethanol-induced behavior in flies and mice, affecting ethanol-induced sedation in both species. However it is not known what other effects EGFR signaling may have on ethanol-in
Externí odkaz:
https://doaj.org/article/db140d8691c14063a07494f56e9a97ad
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51684 (2012)
Habituation is a form of non-associative learning that enables animals to reduce their reaction to repeated harmless stimuli. When exposed to ethanol vapor, Drosophila show an olfactory-mediated startle response characterized by a transient increase
Externí odkaz:
https://doaj.org/article/f0e3600ac42043e599c970f5d526d548
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34559 (2012)
Pavlovian fear conditioning is an associative learning paradigm in which mice learn to associate a neutral conditioned stimulus with an aversive unconditioned stimulus. In this study, we demonstrate a novel role for the transcriptional regulator Lmo4
Externí odkaz:
https://doaj.org/article/ed4a7bd5666b4b5bbcc7975037716210
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50594 (2012)
Neuronal signal transduction by the JNK MAP kinase pathway is altered by a broad array of stimuli including exposure to the widely abused drug ethanol, but the behavioral relevance and the regulation of JNK signaling is unclear. Here we demonstrate t
Externí odkaz:
https://doaj.org/article/cbafb9abeeee4393a51f68f10deb2249
Autor:
Rajani Maiya, Seonok Lee, Karen H Berger, Eric C Kong, Justin B Slawson, Leslie C Griffith, Kogo Takamiya, Richard L Huganir, Ben Margolis, Ulrike Heberlein
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48967 (2012)
From a genetic screen for Drosophila melanogaster mutants with altered ethanol tolerance, we identified intolerant (intol), a novel allele of discs large 1 (dlg1). Dlg1 encodes Discs Large 1, a MAGUK (Membrane Associated Guanylate Kinase) family memb
Externí odkaz:
https://doaj.org/article/f48803c03cd94b598bbfc915c6fb7e48
Autor:
Amy W Lasek, Jana Lim, Christopher L Kliethermes, Karen H Berger, Geoff Joslyn, Gerry Brush, Liquan Xue, Margaret Robertson, Monica S Moore, Karen Vranizan, Stephan W Morris, Marc A Schuckit, Raymond L White, Ulrike Heberlein
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22636 (2011)
Anaplastic lymphoma kinase (Alk) is a gene expressed in the nervous system that encodes a receptor tyrosine kinase commonly known for its oncogenic function in various human cancers. We have determined that Alk is associated with altered behavioral r
Externí odkaz:
https://doaj.org/article/a85a1905315e4389912e69a18a2d5452