Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Ulrike Gaul"'
Autor:
Zhan Qi, Christophe Jung, Peter Bandilla, Claudia Ludwig, Mark Heron, Anja Sophie Kiesel, Mariam Museridze, Julia Philippou‐Massier, Miroslav Nikolov, Alessio Renna Max Schnepf, Ulrich Unnerstall, Stefano Ceolin, Bettina Mühlig, Nicolas Gompel, Johannes Soeding, Ulrike Gaul
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 2, Pp 1-26 (2022)
Abstract The core promoter plays a central role in setting metazoan gene expression levels, but how exactly it “computes” expression remains poorly understood. To dissect its function, we carried out a comprehensive structure–function analysis
Externí odkaz:
https://doaj.org/article/1a921a416e01438aa5f2ba5d3fbc8538
Autor:
Xiaoling Li, Richard Fetter, Tina Schwabe, Christophe Jung, Liren Liu, Hermann Steller, Ulrike Gaul
Publikováno v:
eLife, Vol 10 (2021)
The blood–brain barrier (BBB) of Drosophila comprises a thin epithelial layer of subperineural glia (SPG), which ensheath the nerve cord and insulate it against the potassium-rich hemolymph by forming intercellular septate junctions (SJs). Previous
Externí odkaz:
https://doaj.org/article/1a4165662da7452f9862cb4dcd70373d
Publikováno v:
iScience, Vol 23, Iss 11, Pp 101694- (2020)
Summary: An essential event in gene regulation is the binding of a transcription factor (TF) to its target DNA. Models considering the interactions between the TF and the DNA geometry proved to be successful approaches to describe this binding event,
Externí odkaz:
https://doaj.org/article/1b38da966e3646fabf2d9bbd8f579b0c
Autor:
Max Schnepf, Claudia Ludwig, Peter Bandilla, Stefano Ceolin, Ulrich Unnerstall, Christophe Jung, Ulrike Gaul
Publikováno v:
iScience, Vol 23, Iss 2, Pp - (2020)
Summary: The DNA of eukaryotes is wrapped around histone octamers to form nucleosomes. Although it is well established that the DNA sequence significantly influences nucleosome formation, its precise contribution has remained controversial, partially
Externí odkaz:
https://doaj.org/article/bbd6d83328ff4c26acd7c9a7fad8a478
Autor:
Christophe Jung, Peter Bandilla, Marc von Reutern, Max Schnepf, Susanne Rieder, Ulrich Unnerstall, Ulrike Gaul
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Methods to measure selective transcription factor-DNA binding often lack sensitivity and are not performed in solution. Here the authors develop a method to perform fluorescence anisotropy measurements of transcription factor-DNA binding energies wit
Externí odkaz:
https://doaj.org/article/6de05cf9c14c415c94eeb469a7b93565
Publikováno v:
Biology Open, Vol 6, Iss 2, Pp 232-243 (2017)
During development, many epithelia are formed by a mesenchymal-epithelial transition (MET). Here, we examine the major stages and underlying mechanisms of MET during blood-brain barrier formation in Drosophila. We show that contact with the basal lam
Externí odkaz:
https://doaj.org/article/a33e65807f4641659ff5a1720b12375c
Autor:
Sebastian Wissel, Anja Kieser, Tetsuo Yasugi, Peter Duchek, Elisabeth Roitinger, Joseph Gokcezade, Victoria Steinmann, Ulrike Gaul, Karl Mechtler, Klaus Förstemann, Jürgen A. Knoblich, Ralph A. Neumüller
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 8, Pp 2467-2478 (2016)
Traditional loss-of-function studies in Drosophila suffer from a number of shortcomings, including off-target effects in the case of RNA interference (RNAi) or the stochastic nature of mosaic clonal analysis. Here, we describe minimal in vivo GFP int
Externí odkaz:
https://doaj.org/article/094ae1132e5443c7b3805e8fa878a553
Autor:
Christophe Jung, Peter Bandilla, Marc von Reutern, Max Schnepf, Susanne Rieder, Ulrich Unnerstall, Ulrike Gaul
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
In the original version of this Article, equation three contained a sign error whereby the term RT was added when it should have been subtracted. This has now been corrected in the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/39829594b078435395f55108c898a65e
Autor:
Jens B Bosse, Rudolf Bauerfeind, Leonhard Popilka, Lisa Marcinowski, Martina Taeglich, Christophe Jung, Hannah Striebinger, Jens von Einem, Ulrike Gaul, Paul Walther, Ulrich H Koszinowski, Zsolt Ruzsics
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40585 (2012)
Fluorescent tagging of viral particles by genetic means enables the study of virus dynamics in living cells. However, the study of beta-herpesvirus entry and morphogenesis by this method is currently limited. This is due to the lack of replication co
Externí odkaz:
https://doaj.org/article/c553ce86f2b44ab6bd1aaa3c9333ec6b
Autor:
Mark D Schroeder, Michael Pearce, John Fak, HongQing Fan, Ulrich Unnerstall, Eldon Emberly, Nikolaus Rajewsky, Eric D Siggia, Ulrike Gaul
Publikováno v:
PLoS Biology, Vol 2, Iss 9, p E271 (2004)
The segmentation gene network of Drosophila consists of maternal and zygotic factors that generate, by transcriptional (cross-) regulation, expression patterns of increasing complexity along the anterior-posterior axis of the embryo. Using known bind
Externí odkaz:
https://doaj.org/article/29b71f1c2f3f4d3ab245b67961ff3b36