Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ulrike G. A. Sattler"'
Autor:
Ulrike G. A. Sattler, Elena Favaro, Lisa Koetz, Wolfgang Mueller-Klieser, Stefano Indraccolo, Christian G. Fabian
Publikováno v:
FEBS Journal. 279:882-891
Many solid tumors show a large variability in glycolytic activity and lactate accumulation, which has been correlated with different metastatic spread, radioresistance and patient survival. To investigate potential differences in protein profiles und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40be9f151e3d712b4dbfec2adc07cc6f
https://doi.org/10.1111/j.1742-4658.2012.08479.x
https://doi.org/10.1111/j.1742-4658.2012.08479.x
Publikováno v:
Der Anaesthesist. 56:466-469
This article summarizes data from experimental and clinical oncology which are indicative of a pivotal role of tumor carbohydrate metabolism in malignant behavior and outcome of treatment. In primary tumors, such as cervix carcinomas, head and neck s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4c0576d4995425b432bb5c50ee50c02
https://doi.org/10.1007/s00101-007-1164-2
https://doi.org/10.1007/s00101-007-1164-2
Publikováno v:
Laboratory Investigation. 87:84-92
A novel bioluminescence assay has been developed for measuring pyruvate within sections of snap-frozen tissue in a quantitative manner as well as with a spatial resolution on a microscopical level. The assay was verified via HPLC and two independent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41a5661dc4d6cb76dc5c9391a54564d
https://doi.org/10.1038/labinvest.3700493
https://doi.org/10.1038/labinvest.3700493
Autor:
Ulrike G. A. Sattler, Kristina Goetze, Wolfgang Mueller-Klieser, Andrea Siebers, Daniel Faber, Stefano Indraccolo, Livia Binz, Giorgia Nardo, Christian G. Fabian
Publikováno v:
Cellular oncology (Dordrecht). 38(5)
Malignant transformation of cells is often accompanied by up-regulation of glycolysis-related enzymes and transporters, as well as a distortion of mitochondrial respiration. As a consequence, most malignant tumors utilize high amounts of glucose and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa33d8600406c00554cdedd4df568c92
https://pubmed.ncbi.nlm.nih.gov/26288178
https://pubmed.ncbi.nlm.nih.gov/26288178
Publikováno v:
Signal Transduction. 5:48-54
The nuclear receptor GCNF (NR6A1) is required for embryonic survival and development, and regulation of fertility. We used a transgenic approach to investigate its role in neural differentiation. As model we chose the embryonal carcinoma cell line PC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7d2b4e75dd6542134245b9f4dd25f00
https://doi.org/10.1002/sita.200400041
https://doi.org/10.1002/sita.200400041
Publikováno v:
Brain Energy Metabolism ISBN: 9781493910588
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d8603c4135fd30c4af05519d4bc32d7
https://doi.org/10.1007/978-1-4939-1059-5_9
https://doi.org/10.1007/978-1-4939-1059-5_9
Autor:
Christian, Fabian, Lisa, Koetz, Elena, Favaro, Stefano, Indraccolo, Wolfgang, Mueller-Klieser, Ulrike G A, Sattler
Publikováno v:
The FEBS journal. 279(5)
Many solid tumors show a large variability in glycolytic activity and lactate accumulation, which has been correlated with different metastatic spread, radioresistance and patient survival. To investigate potential differences in protein profiles und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d31542f91d3898ef1a747783a5ef14ef
https://pubmed.ncbi.nlm.nih.gov/22240028
https://pubmed.ncbi.nlm.nih.gov/22240028
Autor:
Ulrike G. A. Sattler, Wolfgang Mueller-Klieser, Sandra S. Meyer, K. Zaleska, Daniel Zips, L.A. Kunz-Schughart, Christian G. Fabian, Ala Yaromina, Michael Baumann
Publikováno v:
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]. 188(5)
High pretreatment tumor lactate content is associated with poor outcome after fractionated irradiation in human squamous cell carcinoma (hSCC) xenografts. Therefore, decreasing lactate content might be a promising approach for increasing tumor radios
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b34a4ed94287e8a1c2ad6dd11db058
https://pubmed.ncbi.nlm.nih.gov/22349632
https://pubmed.ncbi.nlm.nih.gov/22349632
Autor:
Giovanni Esposito, Matteo Curtarello, Egidio Iorio, Elisabetta Zulato, Luca Persano, Giorgia Nardo, Wolfgang Mueller-Klieser, Rossella Canese, Stefano Indraccolo, Barbara Biesalski, Elisabetta Rossi, Oriol Casanovas, Ulrike G. A. Sattler, Elena Favaro, Lidia Moserle, Alberto Amadori, Marika Crescenzi, Oliver Thews, Paola Zanovello
Publikováno v:
Cancer research. 71(12)
VEGF antagonists are now widely used cancer therapeutics, but predictive biomarkers of response or toxicity remain unavailable. In this study, we analyzed the effects of anti-VEGF therapy on tumor metabolism and therapeutic response by using an integ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d8cde101a661acc5809abeaf0a43fc
https://pubmed.ncbi.nlm.nih.gov/21546569
https://pubmed.ncbi.nlm.nih.gov/21546569
Publikováno v:
International journal of radiation biology. 85(11)
In this mini-review data are summarised which provide evidence for the biological and clinical significance of tumour glycolysis and of its relationship to the redox state of cancer cells.Malignant transformation is associated with an overexpression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b16e705f92b6e054f88505e5c73f0856
https://pubmed.ncbi.nlm.nih.gov/19895273
https://pubmed.ncbi.nlm.nih.gov/19895273