Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ulrike Fuhrmann"'
Autor:
Carmen Ulrike Schmid‐Herrmann, Nicole Maria Muschol, Vera Ulrike Fuhrmann, Anja Friederike Koehn, Susanne Lezius, Bärbel Kahl‐Nieke, Till Koehne
Publikováno v:
International Journal of Paediatric Dentistry. 32:737-744
Mucopolysaccharidoses (MPS) are a group of rare metabolic diseases characterized by a wide spectrum of symptoms including progressive condylar resorption.The aim of this study was to quantify the severity of condylar involvement in MPS I individuals
Autor:
Ulrike Fuhrmann, Korolainen Henriikka, Andrea Rotgeri, Katja Prelle, Oskari Sundholm, Frank Sacher, Heinz Schmitz
Publikováno v:
Human Reproduction. 30:308-314
Study question Is it feasible to deliver anastrozole (ATZ), an aromatase inhibitor (AI), by a vaginal polymer-based drug delivery system in the cynomolgus monkey (Macaca fascicularis) to describe the pharmacokinetic profile? Summary answer The presen
This volume gives an overview of state of the art technologies and future developments in the field of preclinical pharmaceutical research. A balanced mix of experts from academia and industry give insight in selected new developments in the drug dis
Publikováno v:
Handbook of experimental pharmacology. 232
Publikováno v:
Handbook of Experimental Pharmacology ISBN: 9783319289120
New Approaches to Drug Discovery
New Approaches to Drug Discovery
Preface.- Part 1. Historical View.- Drug discovery in the past and today.Part 2. Target Discovery.- Emerging target families: intractable targets. In vivo target validation especially for biological targets. HR RNAi/High Content analysis.- Part 3. Le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35f414de03e301e28ec0ff7e4140112f
https://doi.org/10.1007/978-3-319-28914-4
https://doi.org/10.1007/978-3-319-28914-4
Publikováno v:
Expert Opinion on Therapeutic Targets. 16:237-241
Endometriosis (EMS) is a chronic, estrogen-dependent inflammatory disease characterized by growth of endometrial tissue outside the uterine cavity. Symptoms in EMS patients include severe pelvic pain, dysmenorrhea, dyspareunia and infertility. To dat
How sex hormone receptors and all the other members of the nuclear receptor superfamily do such a remarkable job has fascinated scientists for decades. A series of discoveries in the past few years has dramatically enlightened our understanding of th
Autor:
Reiner Strick, Anette Sommer, Oliver Fischer, Stefanie Burghaus, David L. Wachter, Pamela L. Strissel, Matthias W. Beckmann, Ulrike Fuhrmann, Peter A. Fasching, Stefan P. Renner, Abbas Agaimy, Florian Sohler
We identified differentially expressed genes comparing peritoneal endometriosis lesions (n = 18), eutopic endometrium (n = 17), and peritoneum (n = 22) from the same patients with complete menstrual cycles using microarrays (54 675 probe sets) and im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ae0945217d325ef945e13c4d507dbf
https://opus4.kobv.de/opus4-fau/files/4175/sohler_tissue.pdf
https://opus4.kobv.de/opus4-fau/files/4175/sohler_tissue.pdf
Autor:
Guenter Dr Neef, Kristof Chwalisz, Karl-Heinrich Fritzemeier, Wolfgang Schwede, Ulrike Fuhrmann, Jens Hoffmann, Arwed Cleve, Holger Hess-Stumpp
Publikováno v:
Journal of Medicinal Chemistry. 43:5010-5016
Herein we describe the chemical synthesis and pharmacological characterization of a novel, highly potent progesterone receptor (PR) antagonist, ZK 230211. The introduction of a 17alpha-pentafluorethyl side chain in the D-ring of the steroid skeleton
Publikováno v:
Steroids. 65:741-751
Progesterone antagonists (PAs, antiprogestins) can modulate estrogenic effects in various estrogen-dependent tissues. These modulatory effects are complex and depend on species, tissue, type of compound, dose, and duration of treatment. In non-human