Zobrazeno 1 - 10 of 41 pro vyhledávání: '"Ulrike Eggert"'
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Akademický článek
The chromosomal passenger complex activates Polo kinase at centromeres.
Autor: Mar Carmena, Xavier Pinson, Melpi Platani, Zeina Salloum, Zhenjie Xu, Anthony Clark, Fiona Macisaac, Hiromi Ogawa, Ulrike Eggert, David M Glover, Vincent Archambault, William C Earnshaw
Publikováno v: PLoS Biology, Vol 10, Iss 1, p e1001250 (2012)
The coordinated activities at centromeres of two key cell cycle kinases, Polo and Aurora B, are critical for ensuring that the two sister kinetochores of each chromosome are attached to microtubules from opposite spindle poles prior to chromosome seg
Externí odkaz: https://doaj.org/article/d44a914551df4c03a4a1351d1a6845ce
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4
Synthesis of (+)-Omphadiol and (+)-Pyxidatol C
Autor: Gowrisankar Parthasarathy, Markus Kalesse, Ulrike Eggert
Publikováno v: Organic letters. 18(9)
The synthesis of (+)-omphadiol and (+)-pyxidatol C was achieved through two independent strategies. For the synthesis of (+)-omphadiol, dicyclopentadienone was used as the workbench on which the three contiguous stereocenters of the cyclopentane coul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61256083eb588ad8fb6d072013bea034
https://pubmed.ncbi.nlm.nih.gov/27187085
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5
An Improved Route to (+)‐Tedanolide and Analysis of Its Subtle Effects Controlling Conformation and Biological Behaviour
Autor: Markus Kalesse, Mingzhao Zhu, Yazh Muthukumar, Ulrike Eggert, Nina Diaz, Gunnar Ehrlich, Florenz Sasse
Publikováno v: Chemistry – A European Journal. 18:4946-4952
The improved synthesis of the antitumor compound (+)-tedanolide is described through an aldol coupling of bis-ketone 7. This modification shortens the synthetic steps in the endgame and provides rapid access to this biologically important natural pro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c70423dd7a75de72cf402aab2f16a5
https://doi.org/10.1002/chem.201103038
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Synthesis of the C1-C17 Macrolactone of Tedanolide
Autor: Markus Kalesse, Jorma Hassfeld, Ulrike Eggert
Publikováno v: Synthesis. :1183-1199
The vinylogous Mukaiyama aldol reaction is a useful method to build up complex polyketide structures. It is successfully employed in the synthesis of the C1-C17 macrolactone of tedanolide, a highly cytotoxic marine natural product. These studies pres
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::720b5e8f3019f1f8078a880321748650
https://doi.org/10.1055/s-2005-865302
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8
Synthetic studies toward the disorazoles: synthesis of a masked northern half of disorazole D1 and a cyclopropane analog of the masked northern half of disorazole A1
Autor: Sreeletha B Panicker, Barbara Niess, Lars Ole Haustedt, Ingo V. Hartung, H. M. R. Hoffmann, Ulrike Eggert, Mike Kleinert
Publikováno v: Tetrahedron. 59:6967-6977
The synthesis of a masked northern half of the natural product disorazole D1 and a cyclopropane analog of the masked northern half of disorazole A1 is described. The synthesis involves in both cases as key steps a Z-selective Wittig olefination and a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f29159573fb8badc535789fe1bda4fa7
https://doi.org/10.1016/s0040-4020(03)00916-5
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9
Toward the Total Synthesis ofDisorazole A1: Asymmetric Synthesis of the MaskedNorthern Half
Autor: Ulrike Eggert, H. Martin R. Hoffmann, Lars Ole Haustedt, Barbara Niess, Peter M. Schäfer, Ingo V. Hartung
Publikováno v: Synthesis. :1844-1850
The stereoselective synthesis of the masked northern half of the antimitotic natural product disorazole A 1 is described involving as key step a Z-selective Wittig olefination of a Cl -C I epoxy aldehyde with a C12-C19 phosphonium iodide.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::312e5312672a476515b1987ea419f83c
https://doi.org/10.1055/s-2003-41033
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10
New members of the caryophyllene family via biomimetic π-cyclizations and consecutive transformations
Autor: H. Martin R. Hoffmann, Carsten E Sowa, Ulrike Eggert
Publikováno v: Tetrahedron. 49:4183-4192
A series of derivatives from caryophyllene oxide have been prepared in enantiomerically pure form, including bicyclic, tricyclic and tetracyclic sesquiterpenes and sesquiterpenoids. A key intermediate is the unsaturated, chiral (pro 1S,8Z)-bridgehead
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a449b95e64e8f189085da9c93371cdfc
https://doi.org/10.1016/s0040-4020(01)85736-7
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