Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ulrike Bonati"'
Autor:
Amit Bar-Or, Gian-Andrea Thanei, Christopher Harp, Corrado Bernasconi, Ulrike Bonati, Anne H. Cross, Saloumeh Fischer, Laura Gaetano, Stephen L. Hauser, Robert Hendricks, Ludwig Kappos, Jens Kuhle, David Leppert, Fabian Model, Annette Sauter, Harold Koendgen, Xiaoming Jia, Ann E. Herman
Publikováno v:
EBioMedicine, Vol 93, Iss , Pp 104662- (2023)
Summary: Background: Neurofilament light chain (NfL), a neuronal cytoskeletal protein that is released upon neuroaxonal injury, is associated with multiple sclerosis (MS) relapsing activity and has demonstrated some prognostic ability for future rela
Externí odkaz:
https://doaj.org/article/e7ff9f024a2e4966833fd5346456e54f
Autor:
Xing Chen, Juliane Siebourg-Polster, Detlef Wolf, Christian Czech, Ulrike Bonati, Dirk Fischer, Omar Khwaja, Martin Strahm
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170472 (2017)
Although functional rating scales are being used increasingly as primary outcome measures in spinal muscular atrophy (SMA), sensitive and objective assessment of early-stage disease progression and drug efficacy remains challenging. We have developed
Externí odkaz:
https://doaj.org/article/064c0dc62a234960a3a91a48089cb6f7
Autor:
Patricia Hafner, Ulrike Bonati, Beat Erne, Maurice Schmid, Daniela Rubino, Urs Pohlman, Thomas Peters, Erich Rutz, Stephan Frank, Cornelia Neuhaus, Stefanie Deuster, Monika Gloor, Oliver Bieri, Arne Fischmann, Michael Sinnreich, Nuri Gueven, Dirk Fischer
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147634 (2016)
Altered neuronal nitric oxide synthase function in Duchenne muscular dystrophy leads to impaired mitochondrial function which is thought to be one cause of muscle damage in this disease. The study tested if increased intramuscular nitric oxide concen
Externí odkaz:
https://doaj.org/article/75a03bffbfc54fe28bfeb6cb429743ee
Autor:
Shannon Kolind, Laura Gaetano, Haz-Edine Assemlal, Corrado Bernasconi, Ulrike Bonati, Colm Elliott, Niels Hagenbuch, Stefano Magon, Douglas L Arnold, Anthony Traboulsee
Publikováno v:
Multiple Sclerosis Journal. 29:741-747
Background: Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system characterized by two major and interconnected hallmarks: inflammation and progressive neurodegeneration. Objective: The aim of this work was to compare
Autor:
Douglas L Arnold, Till Sprenger, Amit Bar-Or, Jerry S Wolinsky, Ludwig Kappos, Shannon Kolind, Ulrike Bonati, Stefano Magon, Johan van Beek, Harold Koendgen, Oscar Bortolami, Corrado Bernasconi, Laura Gaetano, Anthony Traboulsee
Publikováno v:
Multiple Sclerosis Journal. 28:1927-1936
Background: In multiple sclerosis (MS), thalamic integrity is affected directly by demyelination and neuronal loss, and indirectly by gray/white matter lesions outside the thalamus, altering thalamic neuronal projections. Objective: To assess the eff
Autor:
Rebecca Zhuang, Irene Vavasour, Colm Elliott, Douglas Arnold, David Clayton, Stefano Magon, Ulrike Bonati, Corrado Bernasconi, Laura Gaetano, Anthony Traboulsee, Shannon Kolind
Publikováno v:
Wednesday, April 26.
Autor:
Dirk Fischer, Clemens Bloetzer, Thomas Zumbrunn, Daniela Rubino-Nacht, Guenther Bernert, Ulrike Bonati, Vincent Laugel, Simone Schmidt, Monika Gloor, Vanya Gocheva, Oliver Bieri, Patrick Tobler, Jonas Schroeder, Patricia Hafner, Andrea Capone, Andrea Klein, Arjith Naduvilekoot Devasia, Maja Steinlin, Tanja Haas, Stephanie Zuesli
Publikováno v:
Neuromuscular Disorders. 28:16-23
The development of new therapeutic agents for the treatment of Duchenne muscular dystrophy has put a focus on defining outcome measures most sensitive to capture treatment effects. This cross-sectional analysis investigates the relation between valid
Autor:
Omar Khwaja, Celine Risterucci, Oliver Bieri, Stefan Holiga, Ulrike Bonati, Wakana Tang, Alessandro Bertolino, Juergen Dukart, Dirk Fischer, Patricia Hafner, Alain Thoeni, Tobias Bergauer, Anne Marquet, Irene Gerlach, Christian Czech, Fabio Sambataro, Arne Fischmann, Nicole Hellbach
Publikováno v:
Annals of Clinical and Translational Neurology
Objective Recent advances in understanding Spinal Muscular Atrophy (SMA) etiopathogenesis prompted development of potent intervention strategies and raised need for sensitive outcome measures capable of assessing disease progression and response to t
Autor:
Oliver Bieri, Delia Scherrer, Simone Schmidt, Selina Ebi, Dirk Fischer, Sabine Schädelin, Ulrike Bonati, Sara Nagy, Patricia Hafner, Anna-Lena Orsini
Publikováno v:
MusclenerveREFERENCES. 61(1)
Introduction The definition of reliable outcome measures is of increasing interest in patients with Duchenne muscular dystrophy (DMD). Methods In this retrospective study, we analyzed the longitudinal reliability of clinical and radiological endpoint
Autor:
Vanya Gocheva, Oliver Bieri, Sara Nagy, Carole Vuillerot, Andrea Klein, Simone Schmidt, Daniela Rubino-Nacht, Patricia Hafner, Ulrike Bonati, Dirk Fischer
Publikováno v:
Journal of Visualized Experiments.
While the number of new treatment options tested in patients with Duchenne muscular dystrophy (DMD) is increasing, there is still no defining of the most reliable assessments regarding therapeutic efficacy. We present clinical and radiological outcom