Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Ulrike B. Hendgen-Cotta"'
Autor:
Elias Haj-Yehia, Sebastian Korste, Robert Jochem, Aldona Lusha, Anna Roth, Nina Dietzel, Josefine Niroomand, Pia Stock, Astrid M. Westendorf, Jan Buer, Ulrike B. Hendgen-Cotta, Tienush Rassaf, Matthias Totzeck
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 48, Iss , Pp 101269- (2023)
CD47 is a cell surface protein controlling phagocytotic activity of innate immune cells. CD47 blockade was investigated as an immune checkpoint therapy in cancer treatment, enhancing phagocytosis of tumor cells by macrophages. Anti-CD47 treatment als
Externí odkaz:
https://doaj.org/article/3e38543a33e249afba3fe9903646b023
Autor:
Julia Pohl, Matthias Totzeck, Raluca‐I. Mincu, Simone M. Margraf, Lena Scheipers, Lars Michel, Amir A. Mahabadi, Lisa Zimmer, Tienush Rassaf, Ulrike B. Hendgen‐Cotta
Publikováno v:
ESC Heart Failure, Vol 9, Iss 5, Pp 3533-3542 (2022)
Abstract Aims While immune checkpoint inhibitor (ICI) therapy significantly improves survival rates in advanced melanoma, ICI can evoke severe immune‐related cardiovascular adverse events. Right ventricular (RV) dysfunction negatively impacts the o
Externí odkaz:
https://doaj.org/article/aae44109e7774531bdcef5596b923f82
Autor:
Lisa Christen, Helen Broghammer, Inka Rapöhn, Kevin Möhlis, Christian Strehlau, Aleix Ribas‐Latre, Claudia Gebhardt, Lisa Roth, Kerstin Krause, Kathrin Landgraf, Antje Körner, Kerstin Rohde‐Zimmermann, Anne Hoffmann, Nora Klöting, Adhideb Ghosh, Wenfei Sun, Hua Dong, Christian Wolfrum, Tienush Rassaf, Ulrike B. Hendgen‐Cotta, Michael Stumvoll, Matthias Blüher, John T. Heiker, Juliane Weiner
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 12, Pp n/a-n/a (2022)
Abstract Background Recruitment and activation of brown adipose tissue (BAT) results in increased energy expenditure (EE) via thermogenesis and represents an intriguing therapeutic approach to combat obesity and treat associated diseases. Thermogenes
Externí odkaz:
https://doaj.org/article/3c0531ab79ab4ae08f8a1517269c74c9
Autor:
Jacqueline Heinen‐Weiler, Mike Hasenberg, Martin Heisler, Stephan Settelmeier, Anna‐Lena Beerlage, Hannah Doepper, Bernd Walkenfort, Andrea Odersky, Peter Luedike, Elke Winterhager, Tienush Rassaf, Ulrike B. Hendgen‐Cotta
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 4, Pp 933-954 (2021)
Abstract Background Cardioprotection by preventing or repairing mitochondrial damage is an unmet therapeutic need. To understand the role of cardiomyocyte mitochondria in physiopathology, the reliable characterization of the mitochondrial morphology
Externí odkaz:
https://doaj.org/article/ab252e73ad924d9daf5c898d9cfdf73b
Autor:
Stephan Settelmeier, Zohreh Varasteh, Magdalena Staniszewska, Anna-Lena Beerlage, Fadi Zarrad, Wolfgang P. Fendler, Christoph Rischpler, Johannes Notni, Matthias Totzeck, Ken Herrmann, Tienush Rassaf, Ulrike B. Hendgen-Cotta
Publikováno v:
Pharmaceuticals, Vol 16, Iss 6, p 824 (2023)
The cardiac bioavailability of peptide drugs that inhibit harmful intracellular protein–protein interactions in cardiovascular diseases remains a challenging task in drug development. This study investigates whether a non-specific cell-targeted pep
Externí odkaz:
https://doaj.org/article/71f26396bed24156975fbdf8790bd8ba
Autor:
Sebastian Korste, Stephan Settelmeier, Lars Michel, Andrea Odersky, Pia Stock, Fabrice Reyes, Elias Haj-Yehia, Markus S. Anker, Anika Grüneboom, Ulrike B. Hendgen-Cotta, Tienush Rassaf, Matthias Totzeck
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6052 (2023)
Cancer survival rates have increased significantly because of improvements in therapy regimes and novel immunomodulatory drugs. Recently, combination therapies of anthracyclines and immune checkpoint inhibitors (ICIs) have been proposed to maximize n
Externí odkaz:
https://doaj.org/article/663aacb6082341939843d1d2a1a8eedb
Autor:
Lina S. Farhoumand, Hongtao Liu, Theodora Tsimpaki, Ulrike B. Hendgen-Cotta, Tienush Rassaf, Nikolaos E. Bechrakis, Miltiadis Fiorentzis, Utta Berchner-Pfannschmidt
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5894 (2023)
Uveal melanoma (UM) is the most common primary cancer of the eye in adults. A new systemic therapy is needed to reduce the high metastasis and mortality rate. As β-blockers are known to have anti-tumor effects on various cancer entities, this study
Externí odkaz:
https://doaj.org/article/6566e483f85f44b78e2ccedc69366832
Autor:
Simon F. Merz, Sebastian Korste, Lea Bornemann, Lars Michel, Pia Stock, Anthony Squire, Camille Soun, Daniel R. Engel, Julia Detzer, Holger Lörchner, Dirk M. Hermann, Markus Kamler, Joachim Klode, Ulrike B. Hendgen-Cotta, Tienush Rassaf, Matthias Gunzer, Matthias Totzeck
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Detailed characterization of cardiac damage following ischemia/reperfusion injury and detection of occurring inflammatory responses is important for the development of new therapeutic concepts. Here the authors present a method for the three-dimensio
Externí odkaz:
https://doaj.org/article/3e96cf3e564a4e068419e2da632f2557
Autor:
Joanna Majerczak, Agnieszka Kij, Hanna Drzymala-Celichowska, Kamil Kus, Janusz Karasinski, Zenon Nieckarz, Marcin Grandys, Jan Celichowski, Zbigniew Szkutnik, Ulrike B. Hendgen-Cotta, Jerzy A. Zoladz
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2686 (2022)
Skeletal muscles are an important reservoir of nitric oxide (NO•) stored in the form of nitrite [NO2−] and nitrate [NO3−] (NOx). Nitrite, which can be reduced to NO• under hypoxic and acidotic conditions, is considered a physiologically relev
Externí odkaz:
https://doaj.org/article/ceeb294529c6499898e046ef3235cf8f
Publikováno v:
Cosmetics, Vol 8, Iss 1, p 16 (2021)
Nitric oxide (NO) plays multiple roles in both normal and abnormal skin processes. Its deranging disbalance is involved in the pathogenesis of multiple dermatologic diseases such as acne vulgaris, pointing towards beneficial therapeutic directions. A
Externí odkaz:
https://doaj.org/article/506d51ef7b054f29b81bb3db361705ba