Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Ulrike Böer"'
Autor:
Sarah Zippusch, Axel Haverich, Mathias Wilhelmi, Ulrike Böer, Skadi Lau, Melanie Klingenberg, Thomas Aper, Florian Helms
Publikováno v:
Annals of Biomedical Engineering. 49:2066-2079
The generation of cellularized bioartificial blood vessels resembling all three layers of the natural vessel wall with physiological morphology and cell alignment is a long pursued goal in vascular tissue engineering. Simultaneous culture of all thre
Autor:
Florian Helms, Sarah Zippusch, Thomas Aper, Stefan Kalies, Alexander Heisterkamp, Axel Haverich, Ulrike Böer, Mathias Wilhelmi
Publikováno v:
Tissue engineering. Part A. 28(19-20)
Generation of bioartificial blood vessels with a physiological three-layered wall architecture is a long pursued goal in vascular tissue engineering. While considerable advances have been made to resemble the physiologicalitunica intima/iandimedia/im
Autor:
Florian Helms, Sarah Zippusch, Jonathan Theilen, Axel Haverich, Mathias Wilhelmi, Ulrike Böer
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 119(8)
Facilitating sufficient nutrient and oxygen supply in large-scale bioartificial constructs is a critical step in organ bioengineering. Immediate perfusion not only depends on a dense capillary network, but also requires integrated large-diameter vess
Autor:
Florian Helms, Alexander Horke, Axel Haverich, Melanie Klingenberg, Dmitry Bobylev, Ulrike Böer, Skadi Lau, Thomas Hassel, Markus Mlinaric, Elena Petená, Mathias Wilhelmi
Publikováno v:
Journal of biomaterials applications. 36(6)
Objective: The generation of bio-/hemocompatible cardiovascular patches with sufficient stability and regenerative potential remains an unmet goal. Thus, the aim of this study was the generation and in vitro biomechanical evaluation of a novel cardio
Autor:
Axel Haverich, Florian Helms, Peter Behrens, Melanie Klingenberg, Mathias Wilhelmi, Nina Ehlert, Anne Lyons, Karen F W Besecke, Sarah Zippusch, Ulrike Böer
Publikováno v:
Regenerative Biomaterials
Inadequate vascularization leading to insufficient oxygen and nutrient supply in deeper layers of bioartificial tissues remains a limitation in current tissue engineering approaches to which pre-vascularization offers a promising solution. Hypoxia tr
Autor:
Ulrike Böer, Verena Scheper, Theodor Doll, Suheda Yilmaz-Bayraktar, Thomas Lenarz, Mariela C. Torrente, Michaela Kreienmeyer, Jana Schwieger
Publikováno v:
The International Journal of Artificial Organs
Today’s best solution in compensating for sensorineural hearing loss is the cochlear implant, which electrically stimulates the spiral ganglion neurons in the inner ear. An optimum hearing impression is not ensured due to, among other reasons, a re
Autor:
Melanie Klingenberg, Daniel Sedding, Axel Haverich, Mathias Wilhelmi, Anna Mrugalla, Ulrike Böer, Skadi Lau, Florian Helms
Publikováno v:
Tissue Engineering Part A. 25:936-948
We here showed that even under optimized conditions for biochemical differentiation of adipose-derived stem cells (with respect to a pronounced marker protein expression for a reasonable period of time) it was not possible to obtain functional smooth
Autor:
Thomas Aper, Mathias Wilhelmi, Florian Helms, Ulrike Böer, Melanie Klingenberg, Axel Haverich, Skadi Lau
Publikováno v:
Annals of Biomedical Engineering. 48:913-926
Vascular tissue engineering of the middle layer of natural arteries requires contractile smooth muscle cells (SMC) which can be differentiated from adipose-derived mesenchymal stem cells (ASC) by treatment with transforming growth factor-β, sphingos
Publikováno v:
Journal of the mechanical behavior of biomedical materials. 124
Fibrin is used successfully as a biological matrix in various bioengineering approaches. Its unique combination of autologous availability, hemocompatibility and biological activity makes it an almost ideal matrix material for vascular tissue enginee
Publikováno v:
The Thoracic and Cardiovascular Surgeon.