Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ulrike, Vavra"'
Autor:
Jennifer Schoberer, Shiva Izadi, Carolina Kierein, Ulrike Vavra, Julia König-Beihammer, Valentina Ruocco, Clemens Grünwald-Gruber, Alexandra Castilho, Richard Strasser
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
IntroductionThe Golgi apparatus of plants is the central cellular organelle for glycan processing and polysaccharide biosynthesis. These essential processes are catalyzed by a large number of Golgi-resident glycosyltransferases and glycosidases whose
Externí odkaz:
https://doaj.org/article/d51270cf601b46ce9dacb6de0756f601
Autor:
Valentina Ruocco, Ulrike Vavra, Julia König-Beihammer, Omayra C. Bolaños−Martínez, Somanath Kallolimath, Daniel Maresch, Clemens Grünwald-Gruber, Richard Strasser
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Subunit vaccines based on recombinant viral antigens are valuable interventions to fight existing and evolving viruses and can be produced at large-scale in plant-based expression systems. The recombinant viral antigens are often derived from glycosy
Externí odkaz:
https://doaj.org/article/8506f3bdebaa44bf909cf3ff66e32b66
Autor:
Shiva Izadi, Ulrike Vavra, Stanislav Melnik, Clemens Grünwald-Gruber, Esther Föderl-Höbenreich, Markus Sack, Kurt Zatloukal, Josef Glössl, Eva Stöger, Lukas Mach, Alexandra Castilho, Richard Strasser
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
SARS-CoV-2 infects human cells via binding of the viral spike glycoprotein to its main cellular receptor, angiotensin-converting enzyme 2 (ACE2). The spike protein-ACE2 receptor interaction is therefore a major target for the development of therapeut
Externí odkaz:
https://doaj.org/article/b00aae2617684bc2bb46c3d926f815b9
Autor:
Julia König-Beihammer, Ulrike Vavra, Yun-Ji Shin, Christiane Veit, Clemens Grünwald-Gruber, Yasmin Gillitschka, Jasmin Huber, Manuela Hofner, Klemens Vierlinger, Dieter Mitteregger, Andreas Weinhäusel, Richard Strasser
Publikováno v:
Frontiers in Chemistry, Vol 9 (2022)
Glycosylation of viral envelope proteins is important for infectivity and immune evasion. The SARS-CoV-2 spike protein is heavily glycosylated and host-derived glycan modifications contribute to the formation of specific immunogenic epitopes, enhance
Externí odkaz:
https://doaj.org/article/9b5fc26adc474edfbbd5610459369045
Autor:
Jennifer Schwestka, Julia König-Beihammer, Yun-Ji Shin, Ulrike Vavra, Nikolaus F. Kienzl, Clemens Grünwald-Gruber, Daniel Maresch, Miriam Klausberger, Elisabeth Laurent, Maria Stadler, Gabriele Manhart, Jasmin Huber, Manuela Hofner, Klemens Vierlinger, Andreas Weinhäusel, Ines Swoboda, Christoph J. Binder, Wilhelm Gerner, Florian Grebien, Friedrich Altmann, Lukas Mach, Eva Stöger, Richard Strasser
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
The receptor binding domain (RBD) of the SARS-CoV-2 spike protein plays a key role in the virus-host cell interaction, and viral infection. The RBD is a major target for neutralizing antibodies, whilst recombinant RBD is commonly used as an antigen i
Externí odkaz:
https://doaj.org/article/df218680a37f4783b7a28aaab0e9205d
Autor:
Jennifer Schoberer, Julia König, Christiane Veit, Ulrike Vavra, Eva Liebminger, Stanley W. Botchway, Friedrich Altmann, Verena Kriechbaumer, Chris Hawes, Richard Strasser
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The Arabidopsis ER-α-mannosidase I MNS3 generates N-glycan structures typical of ER-resident glycoproteins. Here Schoberer et al. identify a novel motif that anchors MNS3 to the cis-Golgi, spatially separating MNS3 from ER-localized mannose trimming
Externí odkaz:
https://doaj.org/article/ae45cf92025043e39d2f6156ceaa447d
Autor:
Yun-Ji Shin, Julia König-Beihammer, Ulrike Vavra, Jennifer Schwestka, Nikolaus F. Kienzl, Miriam Klausberger, Elisabeth Laurent, Clemens Grünwald-Gruber, Klemens Vierlinger, Manuela Hofner, Emmanuel Margolin, Andreas Weinhäusel, Eva Stöger, Lukas Mach, Richard Strasser
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
Nicotiana benthamiana is used worldwide as production host for recombinant proteins. Many recombinant proteins such as monoclonal antibodies, growth factors or viral antigens require posttranslational modifications like glycosylation for their functi
Externí odkaz:
https://doaj.org/article/f0fc36b17a124f02b7ee407aa0a98189
Autor:
Miriam Klausberger, Mark Duerkop, Helmuth Haslacher, Gordana Wozniak-Knopp, Monika Cserjan-Puschmann, Thomas Perkmann, Nico Lingg, Patricia Pereira Aguilar, Elisabeth Laurent, Jelle De Vos, Manuela Hofner, Barbara Holzer, Maria Stadler, Gabriele Manhart, Klemens Vierlinger, Margot Egger, Lisa Milchram, Elisabeth Gludovacz, Nicolas Marx, Christoph Köppl, Christopher Tauer, Jürgen Beck, Daniel Maresch, Clemens Grünwald-Gruber, Florian Strobl, Peter Satzer, Gerhard Stadlmayr, Ulrike Vavra, Jasmin Huber, Markus Wahrmann, Farsad Eskandary, Marie-Kathrin Breyer, Daniela Sieghart, Peter Quehenberger, Gerda Leitner, Robert Strassl, Alexander E. Egger, Christian Irsara, Andrea Griesmacher, Gregor Hoermann, Günter Weiss, Rosa Bellmann-Weiler, Judith Loeffler-Ragg, Nicole Borth, Richard Strasser, Alois Jungbauer, Rainer Hahn, Jürgen Mairhofer, Boris Hartmann, Nikolaus B. Binder, Gerald Striedner, Lukas Mach, Andreas Weinhäusel, Benjamin Dieplinger, Florian Grebien, Wilhelm Gerner, Christoph J. Binder, Reingard Grabherr
Publikováno v:
EBioMedicine, Vol 67, Iss , Pp 103348- (2021)
Background: Antibody tests are essential tools to investigate humoral immunity following SARS-CoV-2 infection or vaccination. While first-generation antibody tests have primarily provided qualitative results, accurate seroprevalence studies and track
Externí odkaz:
https://doaj.org/article/ba1f6bc358354ac0a5baccc4ebc09bec
Publikováno v:
Plant Physiol
Endoplasmic reticulum (ER) quality control processes recognize and eliminate misfolded proteins to maintain cellular protein homeostasis and prevent the accumulation of defective proteins in the secretory pathway. Glycosylphosphatidylinositol (GPI)-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b29cc8b6f8bc46e74a8b5e48a0b6038
https://doi.org/10.1093/plphys/kiab181
https://doi.org/10.1093/plphys/kiab181
Autor:
Vanessa Monteil, Shiva Izadi, Gerald Wirnsberger, Clemens Grünwald-Gruber, Janine Niederhöfer, Lukas Mach, Richard Strasser, Ali Mirazimi, Jennifer Schwestka, Alexandra Castilho, Eva Stoger, Nikolaus F. Kienzl, Chaitra Hiremath, Elisabeth Laurent, Ulrike Vavra, Johannes Stadlmann
Publikováno v:
Biotechnology Journal
Human angiotensin‐converting enzyme 2 (ACE2) is the primary host cell receptor for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) binding and cell entry. Administration of high concentrations of soluble ACE2 can be utilized as a d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1c24928f332aa4654964d158232376
http://europepmc.org/articles/PMC7995010
http://europepmc.org/articles/PMC7995010