Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Ulrike, Obst"'
Autor:
Korbinian Sinzinger, Ulrike Obst, Samed Güner, Manuel Döring, Magdalena Haslbeck, Doris Schieder, Volker Sieber
Publikováno v:
Journal of Bioresources and Bioproducts, Vol 9, Iss 1, Pp 43-57 (2024)
The demand for industrial enzymes is continually rising, fueled by the growing need to shift towards more sustainable industrial processes. However, making efficient enzyme production strains and identifying optimal enzyme expression conditions remai
Externí odkaz:
https://doaj.org/article/2e90d5a6f51a42cab34783315d2d8df9
Autor:
Amy C. Thomas, Elizabeth Oliver, Holly E. Baum, Kapil Gupta, Kathryn L. Shelley, Anna E. Long, Hayley E. Jones, Joyce Smith, Benjamin Hitchings, Natalie di Bartolo, Kate Vasileiou, Fruzsina Rabi, Hanin Alamir, Malak Eghleilib, Ore Francis, Jennifer Oliver, Begonia Morales-Aza, Ulrike Obst, Debbie Shattock, Rachael Barr, Lucy Collingwood, Kaltun Duale, Niall Grace, Guillaume Gonnage Livera, Lindsay Bishop, Harriet Downing, Fernanda Rodrigues, Nicholas Timpson, Caroline L. Relton, Ashley Toye, Derek N. Woolfson, Imre Berger, Anu Goenka, Andrew D. Davidson, Kathleen M. Gillespie, Alistair J. K. Williams, Mick Bailey, Ellen Brooks-Pollock, Adam Finn, Alice Halliday, the CoMMinS Study Team
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-14 (2023)
Thomas et al. test 6 ELISAs detecting IgA and IgG antibodies to whole SARS-CoV-2 spike protein, to its receptor binding domain region and to nucleocapsid protein in saliva. Across 20 household outbreaks, antibody responses are heterogeneous, but a re
Externí odkaz:
https://doaj.org/article/55c6b79ee60943e99ecc0c4b2dc196bb
Autor:
William M. Dawson, Kathryn L. Shelley, Jordan M. Fletcher, D. Arne Scott, Lucia Lombardi, Guto G. Rhys, Tania J. LaGambina, Ulrike Obst, Antony J. Burton, Jessica A. Cross, George Davies, Freddie J. O. Martin, Francis J. Wiseman, R. Leo Brady, David Tew, Christopher W. Wood, Derek N. Woolfson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Differential sensing aims to mimic senses such as taste and smell through the use of synthetic receptors. Here, the authors show that arrays of de novo designed peptide assemblies can be used as sensor components to distinguish various analytes and c
Externí odkaz:
https://doaj.org/article/a820f403adc549ffa2b3bf2e841354ca
Autor:
Alice Halliday, Anna E. Long, Holly E. Baum, Amy C. Thomas, Kathryn L. Shelley, Elizabeth Oliver, Kapil Gupta, Ore Francis, Maia Kavanagh Williamson, Natalie Di Bartolo, Matthew J. Randell, Yassin Ben-Khoud, Ilana Kelland, Georgina Mortimer, Olivia Ball, Charlie Plumptre, Kyla Chandler, Ulrike Obst, Massimiliano Secchi, Lorenzo Piemonti, Vito Lampasona, Joyce Smith, Michaela Gregorova, Lea Knezevic, Jane Metz, Rachael Barr, Begonia Morales-Aza, Jennifer Oliver, Lucy Collingwood, Benjamin Hitchings, Susan Ring, Linda Wooldridge, Laura Rivino, Nicholas Timpson, Jorgen McKernon, Peter Muir, Fergus Hamilton, David Arnold, Derek N. Woolfson, Anu Goenka, Andrew D. Davidson, Ashley M. Toye, Imre Berger, Mick Bailey, Kathleen M. Gillespie, Alistair J. K. Williams, Adam Finn
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Low-volume antibody assays can be used to track SARS-CoV-2 infection rates in settings where active testing for virus is limited and remote sampling is optimal. We developed 12 ELISAs detecting total or antibody isotypes to SARS-CoV-2 nucleocapsid, s
Externí odkaz:
https://doaj.org/article/305a69f5b981428bab7c739f99a8b141
Autor:
Leenah Alaalm, Julia L. Crunden, Mark Butcher, Ulrike Obst, Ryann Whealy, Carolyn E. Williamson, Heath E. O’Brien, Christiane Schaffitzel, Gordon Ramage, James Spencer, Stephanie Diezmann
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
The highly conserved, ubiquitous molecular chaperone Hsp90 is a key regulator of cellular proteostasis and environmental stress responses. In human pathogenic fungi, which kill more than 1.6 million patients each year worldwide, Hsp90 governs cellula
Externí odkaz:
https://doaj.org/article/ca17f57cc0c64ecf8c292a3a3f97e118
Publikováno v:
Journal of Medical Education and Curricular Development, Vol 8 (2021)
Purpose: In this longitudinal study, we investigated the development of empathy during medical education and assessed potential predictors of empathy at different time points in the course of medical studies. Methods: In our longitudinal study, start
Externí odkaz:
https://doaj.org/article/0d56d7be5986444ca26e1b4b7019b6f9
Autor:
Ulrike Obst-Sander, Antonio Ricci, Bernd Kuhn, Thomas Friess, Philipp Koldewey, Andreas Kuglstatter, David Hewings, Annick Goergler, Sandra Steiner, Daniel Rueher, Marie-Paule Imhoff, Noemi Raschetti, Hans-Peter Marty, Aline Dietzig, Caroline Rynn, Andreas Ehler, Dominique Burger, Martin Kornacker, Jeannine Petrig Schaffland, Frank Herting, William Pao, James R. Bischoff, Bruno Martoglio, Yvonne Alice Nagel, Georg Jaeschke
Publikováno v:
Journal of Medicinal Chemistry. 65:13052-13073
Addressing resistance to third-generation EGFR TKIs such as osimertinib via the EGFR
Publikováno v:
ChemMedChem. 16:2760-2763
We retrace Prof. François Diederich's consultancy work for Roche and its impact over the years he worked with us. François Diederich uniquely shaped our approach to molecular design, and interactions with him and his research group at ETH Zurich ha
Autor:
Ryann Whealy, Julia L. Crunden, Christiane Schaffitzel, Carolyn E. Williamson, Ulrike Obst, Leenah Alaalm, Mark C. Butcher, Heath E. O’Brien, James Spencer, Stephanie Diezmann, Gordon Ramage
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Alaalm, L, Crunden, J L, Butcher, M, Obst, U, Whealy, R, Williamson, C, O'Brien, H, Berger-Schaffitzel, C H, Ramage, G, Spencer, J & Diezmann, S 2021, ' Identification and Phenotypic Characterization of Hsp90 Phosphorylation Sites That Modulate Virulence Traits in the Major Human Fungal Pathogen Candida albicans ', Frontiers in Cellular and Infection Microbiology, vol. 11, 637836 . https://doi.org/10.3389/fcimb.2021.637836
Alaalm, L, Crunden, J L, Butcher, M, Obst, U, Whealy, R, Williamson, C, O'Brien, H, Berger-Schaffitzel, C H, Ramage, G, Spencer, J & Diezmann, S 2021, ' Identification and Phenotypic Characterization of Hsp90 Phosphorylation Sites That Modulate Virulence Traits in the Major Human Fungal Pathogen Candida albicans ', Frontiers in Cellular and Infection Microbiology, vol. 11, 637836 . https://doi.org/10.3389/fcimb.2021.637836
The highly conserved, ubiquitous molecular chaperone Hsp90 is a key regulator of cellular proteostasis and environmental stress responses. In human pathogenic fungi, which kill more than 1.6 million patients each year worldwide, Hsp90 governs cellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bda6025d9c09fdff3737256c6e8c53f0
https://eprints.gla.ac.uk/242766/1/242766.pdf
https://eprints.gla.ac.uk/242766/1/242766.pdf
Autor:
Leenah, Alaalm, Julia L, Crunden, Mark, Butcher, Ulrike, Obst, Ryann, Whealy, Carolyn E, Williamson, Heath E, O'Brien, Christiane, Schaffitzel, Gordon, Ramage, James, Spencer, Stephanie, Diezmann
Publikováno v:
Frontiers in Cellular and Infection Microbiology
The highly conserved, ubiquitous molecular chaperone Hsp90 is a key regulator of cellular proteostasis and environmental stress responses. In human pathogenic fungi, which kill more than 1.6 million patients each year worldwide, Hsp90 governs cellula