Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Ulrike, Korf"'
Autor:
Chiara Giacomelli, Janine Jung, Astrid Wachter, Susanne Ibing, Rainer Will, Stefan Uhlmann, Heiko Mannsperger, Özgür Sahin, Yosef Yarden, Tim Beißbarth, Ulrike Korf, Cindy Körner, Stefan Wiemann
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-19 (2021)
Abstract Background Triple negative breast cancer (TNBC) is the most aggressive subtype of breast cancer (BC). Treatment options for TNBC patients are limited and further insights into disease aetiology are needed to develop better therapeutic approa
Externí odkaz:
https://doaj.org/article/ece14dc9183445a5b9d8d24f84fd4050
Autor:
Adam Byron, Stephan Bernhardt, Bérèngere Ouine, Aurélie Cartier, Kenneth G. Macleod, Neil O. Carragher, Vonick Sibut, Ulrike Korf, Bryan Serrels, Leanne de Koning
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Reverse-phase protein array (RPPA) technology uses panels of high-specificity antibodies to measure proteins and protein post-translational modifications in cells and tissues. The approach offers sensitive and precise quantification of large
Externí odkaz:
https://doaj.org/article/07e3b471ccaf448185223b213fb7f35a
Autor:
Stephan Bernhardt, Michaela Bayerlová, Martina Vetter, Astrid Wachter, Devina Mitra, Volker Hanf, Tilmann Lantzsch, Christoph Uleer, Susanne Peschel, Jutta John, Jörg Buchmann, Edith Weigert, Karl-Friedrich Bürrig, Christoph Thomssen, Ulrike Korf, Tim Beissbarth, Stefan Wiemann, Eva Johanna Kantelhardt
Publikováno v:
Breast Cancer Research, Vol 19, Iss 1, Pp 1-14 (2017)
Abstract Background Breast cancer tumors are known to be highly heterogeneous and differences in their metabolic phenotypes, especially at protein level, are less well-understood. Profiling of metabolism-related proteins harbors the potential to esta
Externí odkaz:
https://doaj.org/article/c0b3d072a2094cbb8715d885c5891d44
Autor:
Roni Golan-Lavi, Chiara Giacomelli, Garold Fuks, Amit Zeisel, Johanna Sonntag, Sanchari Sinha, Wolfgang Köstler, Stefan Wiemann, Ulrike Korf, Yosef Yarden, Eytan Domany
Publikováno v:
Cell Reports, Vol 18, Iss 13, Pp 3129-3142 (2017)
Protein responses to extracellular cues are governed by gene transcription, mRNA degradation and translation, and protein degradation. In order to understand how these time-dependent processes cooperate to generate dynamic responses, we analyzed the
Externí odkaz:
https://doaj.org/article/dacaabb334474b1cb43b27912f46eb1d
Autor:
Silvia von der Heyde, Johanna Sonntag, Daniel Kaschek, Christian Bender, Johannes Bues, Astrid Wachter, Jens Timmer, Ulrike Korf, Tim Beißbarth
Publikováno v:
BioTechniques, Vol 57, Iss 3, Pp 125-135 (2014)
Analysis of large-scale proteomic data sets requires specialized software tools, tailored toward the requirements of individual approaches. Here we introduce an extension of an open-source software solution for analyzing reverse phase protein array (
Externí odkaz:
https://doaj.org/article/36f3c99b5b6d499ea1285e944671061d
Autor:
Vonick Sibut, Stephan Bernhardt, Leanne de Koning, Bérengère Ouine, Ulrike Korf, Neil O. Carragher, Bryan Serrels, Kenneth G. MacLeod, Aurélie Cartier, Adam Byron
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Byron, A, Bernhardt, S, Ouine, B, Cartier, A, Macleod, K G, Carragher, N O, Sibut, V, Korf, U, Serrels, B & Koning, L D 2020, ' Integrative analysis of multi-platform reverse-phase protein array data for the pharmacodynamic assessment of response to targeted therapies ', Scientific Reports, vol. 10, no. 1, 21985, pp. 1-12 . https://doi.org/10.1038/s41598-020-77335-0
Byron, A, Bernhardt, S, Ouine, B, Cartier, A, Macleod, K, Carragher, N O, Sibut, V, Korf, U, Serrels, B & de Koning, L 2020, ' Integrative analysis of multi-platform reverse-phase protein array data for the pharmacodynamic assessment of response to targeted therapies ', Scientific Reports . https://doi.org/10.1038/s41598-020-77335-0
Scientific Reports
Byron, A, Bernhardt, S, Ouine, B, Cartier, A, Macleod, K G, Carragher, N O, Sibut, V, Korf, U, Serrels, B & Koning, L D 2020, ' Integrative analysis of multi-platform reverse-phase protein array data for the pharmacodynamic assessment of response to targeted therapies ', Scientific Reports, vol. 10, no. 1, 21985, pp. 1-12 . https://doi.org/10.1038/s41598-020-77335-0
Byron, A, Bernhardt, S, Ouine, B, Cartier, A, Macleod, K, Carragher, N O, Sibut, V, Korf, U, Serrels, B & de Koning, L 2020, ' Integrative analysis of multi-platform reverse-phase protein array data for the pharmacodynamic assessment of response to targeted therapies ', Scientific Reports . https://doi.org/10.1038/s41598-020-77335-0
Reverse-phase protein array (RPPA) technology uses panels of high-specificity antibodies to measure proteins and protein post-translational modifications in cells and tissues. The approach offers sensitive and precise quantification of large numbers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0bcd575568c59b911f4eef0f2aabd44
https://doaj.org/article/07e3b471ccaf448185223b213fb7f35a
https://doaj.org/article/07e3b471ccaf448185223b213fb7f35a
Autor:
Bleckmann, Kerstin Menck, Darius Wlochowitz, Astrid Wachter, Lena-Christin Conradi, Alexander Wolff, Andreas Scheel, Ulrike Korf, Stefan Wiemann, Hans-Ulrich Schildhaus, Hanibal Bohnenberger, Edgar Wingender, Tobias Pukrop, Kia Homayounfar, Tim Beißbarth, Annalen
Publikováno v:
Cancers; Volume 14; Issue 9; Pages: 2084
Seventy percent of patients with colorectal cancer develop liver metastases (CRLM), which are a decisive factor in cancer progression. Therapy outcome is largely influenced by tumor heterogeneity, but the intra- and inter-patient heterogeneity of CRL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::5b9f4dd268a093e333509b88540478bd
Autor:
Svenja Kemmer, Mireia Berdiel-Acer, Eileen Reinz, Johanna Sonntag, Nooraldeen Tarade, Stephan Bernhardt, Mirjam Fehling-Kaschek, Max Hasmann, Ulrike Korf, Stefan Wiemann, Jens Timmer
Publikováno v:
Cancers; Volume 14; Issue 10; Pages: 2379
Targeted therapies have shown striking success in the treatment of cancer over the last years. However, their specific effects on an individual tumor appear to be varying and difficult to predict. Using an integrative modeling approach that combines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6247dda2b84d1811ffda59b8c5614b6b
https://pubmed.ncbi.nlm.nih.gov/35625984
https://pubmed.ncbi.nlm.nih.gov/35625984
Autor:
Kerstin, Menck, Darius, Wlochowitz, Astrid, Wachter, Lena-Christin, Conradi, Alexander, Wolff, Andreas H, Scheel, Ulrike, Korf, Stefan, Wiemann, Hans-Ulrich, Schildhaus, Hanibal, Bohnenberger, Edgar, Wingender, Tobias, Pukrop, Kia, Homayounfar, Tim, Beißbarth, Annalen, Bleckmann
Publikováno v:
Cancers. 14(9)
Seventy percent of patients with colorectal cancer develop liver metastases (CRLM), which are a decisive factor in cancer progression. Therapy outcome is largely influenced by tumor heterogeneity, but the intra- and inter-patient heterogeneity of CRL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ae995389e17d62eeba286ee7621d99e0
https://pubmed.ncbi.nlm.nih.gov/35565214
https://pubmed.ncbi.nlm.nih.gov/35565214
Autor:
Stefan Uhlmann, Heiko Mannsperger, Jitao David Zhang, Emöke‐Ágnes Horvat, Christian Schmidt, Moritz Küblbeck, Frauke Henjes, Aoife Ward, Ulrich Tschulena, Katharina Zweig, Ulrike Korf, Stefan Wiemann, Özgür Sahin
Publikováno v:
Molecular Systems Biology, Vol 8, Iss 1, Pp 1-15 (2012)
Abstract The EGFR‐driven cell‐cycle pathway has been extensively studied due to its pivotal role in breast cancer proliferation and pathogenesis. Although several studies reported regulation of individual pathway components by microRNAs (miRNAs),
Externí odkaz:
https://doaj.org/article/67d27a35cf5f4b32a235721de563dc85