Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Ulrike, Garscha"'
Autor:
Céline Tolksdorf, Andrea Seidel, Christian Baume, Eileen Moritz, Karen Saljé, Kathrin Lehmann, Karsten Becker, Ulrike Garscha, Thomas Thiele, Edzard Schwedhelm, Mirjam von Lucadou, Mladen V. Tzvetkov, Stefan Engeli, Gabriele Jedlitschky, Bernhard H. Rauch
Publikováno v:
Platelets, Vol 35, Iss 1 (2024)
Viral infections can lead to platelet activation and hemostatic complications. However, the extent to which platelet reactivity remains altered after convalescence, contributing to long-term health impairments as observed after COVID-19 is not yet fu
Externí odkaz:
https://doaj.org/article/29ead04519cb4821897fc2cf247ef46a
Autor:
Lisa Vieider, Eva Zoeller, Erik Romp, Martin Schoenthaler, Victor Hernández-Olmos, Veronika Temml, Thomas Hasenoehrl, Daniela Schuster, Oliver Werz, Ulrike Garscha, Barbara Matuszczak
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1752-1764 (2022)
A series of derivatives of the potent dual soluble epoxide hydrolase (sEH)/5-lipoxygenase-activating protein (FLAP) inhibitor diflapolin was designed, synthesised, and characterised. These novel compounds, which contain a benzimidazole subunit were e
Externí odkaz:
https://doaj.org/article/64d4071fa89c41b3835b8c14b9c7eab6
Publikováno v:
Metabolites, Vol 12, Iss 12, p 1198 (2022)
Eicosanoids are lipid mediators generated from arachidonic acid with pro- and anti-inflammatory properties. Despite these lipid mediators being known for decades, quantitative determination in biological samples is still challenging due to low abunda
Externí odkaz:
https://doaj.org/article/d2b7bcf5412f4b3db4fe7e1c0c80cb7f
Autor:
Helmut Pein, Alexia Ville, Simona Pace, Veronika Temml, Ulrike Garscha, Martin Raasch, Khaled Alsabil, Guillaume Viault, Chau-Phi Dinh, David Guilet, Fabiana Troisi, Konstantin Neukirch, Stefanie König, Rosella Bilancia, Birgit Waltenberger, Hermann Stuppner, Maria Wallert, Stefan Lorkowski, Christina Weinigel, Silke Rummler, Marc Birringer, Fiorentina Roviezzo, Lidia Sautebin, Jean-Jacques Helesbeux, Denis Séraphin, Alexander S. Mosig, Daniela Schuster, Antonietta Rossi, Pascal Richomme, Oliver Werz, Andreas Koeberle
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Vitamin E metabolites are proposed to have signalling capacity, but how they may regulate immune responses is still unclear. Here the authors show that a vitamin E metabolite, α-T-13′-COOH, can inhibit 5-lipoxygenase and thereby suppress the synth
Externí odkaz:
https://doaj.org/article/8f5b1e43017943509f14b4b68fe07ec5
Autor:
Tarvi Teder, Stefanie König, Rajkumar Singh, Bengt Samuelsson, Oliver Werz, Ulrike Garscha, Jesper Z. Haeggström
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7539
The 5-lipoxygenase (5-LOX) pathway gives rise to bioactive inflammatory lipid mediators, such as leukotrienes (LTs). 5-LOX carries out the oxygenation of arachidonic acid to the 5-hydroperoxy derivative and then to the leukotriene A4 epoxide which is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d6afa8d0080e2389a95c987901e46d
Autor:
Martin Schoenthaler, Lorenz Waltl, Thomas Hasenoehrl, David Seher, Anna Lutz, Lucia Aulinger, Veronika Temml, Stefanie König, Anita Siller, Doris Braun, Ulrike Garscha, Oliver Werz, Daniela Schuster, Harald Schennach, Andreas Koeberle, Barbara Matuszczak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::313530ee8586e79f23a829b283399c21
https://doi.org/10.2139/ssrn.4442671
https://doi.org/10.2139/ssrn.4442671
Autor:
Céline, Tolksdorf, Eileen, Moritz, Robert, Wolf, Ulrike, Meyer, Sascha, Marx, Sandra, Bien-Möller, Ulrike, Garscha, Gabriele, Jedlitschky, Bernhard H, Rauch
Publikováno v:
International journal of molecular sciences. 23(18)
Sphingosine-1-phosphate (S1P) is a versatile signaling lipid involved in the regulation of numerous cellular processes. S1P regulates cellular proliferation, migration, and apoptosis as well as the function of immune cells. S1P is generated from sphi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45d28d90678e6e81ae5f6b7da4749401
https://pubmed.ncbi.nlm.nih.gov/36142188
https://pubmed.ncbi.nlm.nih.gov/36142188
Autor:
Simone Di Micco, Stefania Terracciano, Martina Pierri, Vincenza Cantone, Stefanie Liening, Stefanie König, Ulrike Garscha, Robert Klaus Hofstetter, Andreas Koeberle, Oliver Werz, Ines Bruno, Giuseppe Bifulco
We identified 2,4-dinitro-biphenyl-based compounds as new inhibitors of leukotriene C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ceb5a80e3531a94abb7d329da1adae7
https://hdl.handle.net/11386/4808911
https://hdl.handle.net/11386/4808911
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 11, Pp 1995-2004 (2011)
Seven Z-octadecenoic acids having the double bond located in positions 6Z to 13Z were photooxidized. The resulting hydroperoxy-E-octadecenoic acids [HpOME(E)] were resolved by chiral phase-HPLC-MS, and the absolute configurations of the enantiomers w
Externí odkaz:
https://doaj.org/article/69e875a5b7224c2596e61af10e5b2fb8
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(10)
Neutrophils are the most abundant leukocytes in circulation playing a key role in acute inflammation during microbial infections. Phagocytosis, one of the crucial defence mechanisms of neutrophils against pathogens, is amplified by chemotactic leukot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9853e39cea1c7414a53a32f2e240ded
https://pubmed.ncbi.nlm.nih.gov/34569657
https://pubmed.ncbi.nlm.nih.gov/34569657