Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ulrika Norin"'
Autor:
Ulrika Norin, Carola Rintisch, Liesu Meng, Florian Forster, Diana Ekman, Jonatan Tuncel, Katrin Klocke, Johan Bäcklund, Min Yang, Michael Y. Bonner, Gonzalo Fernandez Lahore, Jaime James, Klementy Shchetynsky, Maria Bergquist, Inger Gjertsson, Norbert Hubner, Liselotte Bäckdahl, Rikard Holmdahl
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The autoimmune disorder, rheumatoid arthritis (RA), has been associated with multiple pathophysiological factors. Here the authors show that deficiency in endophilin A2 in rodents protects them from experimental arthritis by altering T cell activatio
Externí odkaz:
https://doaj.org/article/2c060b0a7c8b44caaf676f45fd6b218d
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008788 (2020)
The control of chronic inflammation is dependent on the possibility of limiting bystander activation of autoreactive and potentially pathogenic T cells. We have identified a non-sense loss of function single nucleotide polymorphism in the C-type lect
Externí odkaz:
https://doaj.org/article/31771220dbfd44ed9889af9288574917
Autor:
Kaja Eriksson, Erik Lönnblom, Gregory Tour, Anna Kats, Piotr Mydel, Pierre Georgsson, Catharina Hultgren, Nastya Kharlamova, Ulrika Norin, Jörgen Jönsson, Anna Lundmark, Annelie Hellvard, Karin Lundberg, Leif Jansson, Rikard Holmdahl, Tülay Yucel-Lindberg
Publikováno v:
Journal of Translational Medicine, Vol 14, Iss 1, Pp 1-14 (2016)
Abstract Background An infection-immune association of periodontal disease with rheumatoid arthritis has been suggested. This study aimed to investigate the effect of pre-existing periodontitis on the development and the immune/inflammatory response
Externí odkaz:
https://doaj.org/article/f38aba8225b94c35af4fdb8c86813b92
Autor:
Jonatan Tuncel, Sabrina Haag, Anthony C Y Yau, Ulrika Norin, Amelie Baud, Erik Lönnblom, Klio Maratou, A Jimmy Ytterberg, Diana Ekman, Soley Thordardottir, Martina Johannesson, Alan Gillett, EURATRANS Consortium, Pernilla Stridh, Maja Jagodic, Tomas Olsson, Alberto Fernández-Teruel, Roman A Zubarev, Richard Mott, Timothy J Aitman, Jonathan Flint, Rikard Holmdahl
Publikováno v:
PLoS Genetics, Vol 10, Iss 2, p e1004151 (2014)
Genetic variation in the major histocompatibility complex (MHC) affects CD4∶CD8 lineage commitment and MHC expression. However, the contribution of specific genes in this gene-dense region has not yet been resolved. Nor has it been established whet
Externí odkaz:
https://doaj.org/article/626b76e763964d4b96c17efc72bbb0ba
Autor:
Jonatan Tuncel, Florian Forster, Klementy Shchetynsky, Liselotte Bäckdahl, Liesu Meng, Inger Gjertsson, Norbert Hubner, Rikard Holmdahl, Michael Y. Bonner, Johan Bäcklund, Ulrika Norin, Min Yang, Jaime James, Katrin Klocke, Maria Bergquist, Gonzalo Fernandez Lahore, Diana Ekman, Carola Rintisch
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The introduction of the CTLA-4 recombinant fusion protein has demonstrated therapeutic effects by selectively modulating T-cell activation in rheumatoid arthritis. Here we show, using a forward genetic approach, that a mutation in the SH3gl1 gene enc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91549c95f91a24bfe26fa5795ca6c7f
http://edoc.mdc-berlin.de/19925/2/19925suppl.zip
http://edoc.mdc-berlin.de/19925/2/19925suppl.zip
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008788 (2020)
PLoS Genetics
PLoS Genetics
The control of chronic inflammation is dependent on the possibility of limiting bystander activation of autoreactive and potentially pathogenic T cells. We have identified a non-sense loss of function single nucleotide polymorphism in the C-type lect
Autor:
Alexandra Gyllenberg, Amennai Daniel Beyeen, Maja Jagodic, Rasmus Berglund, Abdelhadi Saoudi, Ulrika Norin, Elisabeth Petit-Teixeira, François Cornelis, Lars Alfredsson, Lars Klareskog, André Ortlieb Guerreiro-Cacais, Leonid Padyukov, Tomas Olsson, Gilbert J. Fournié, Ingrid Kockum, Rikard Holmdahl
Publikováno v:
Genes and Immunity
Genes and Immunity, Nature Publishing Group: Open Access Hybrid Model Option B, 2017, 18 (1), pp.48--56. ⟨10.1038/gene.2016.49⟩
Genes and Immunity, 2017, 18 (1), pp.48--56. ⟨10.1038/gene.2016.49⟩
Genes and Immunity, Nature Publishing Group: Open Access Hybrid Model Option B, 2017, 18 (1), pp.48--56. ⟨10.1038/gene.2016.49⟩
Genes and Immunity, 2017, 18 (1), pp.48--56. ⟨10.1038/gene.2016.49⟩
International audience; Rheumatoid arthritis (RA) patients can be stratified into two subgroups defined by the presence or absence of antibodies against citrullinated circular peptides (anti-CCP) with most of the genetic association found in anti-CCP
Autor:
Ulrika Norin, Sabrina Haag, Anthony C. Y. Yau, Miranda Houtman, Leonid Padyukov, Rikard Holmdahl, Jonatan Tuncel
Publikováno v:
Proceedings of the National Academy of Sciences. 113
Genome-wide association studies have revealed many genetic loci associated with complex autoimmune diseases. In rheumatoid arthritis (RA), the MHC gene HLA-DRB1 is the strongest candidate predicting disease development. It has been suggested that oth
Autor:
Peter Olofsson, Rikard Holmdahl, Ulrika Norin, Tiina Kelkka, Carola Rintisch, Johnny C. Lorentzen
Publikováno v:
Genes & Immunity. 11:239-245
In this study, we sought to determine the effect of the quantitative trait locus Pia7 on arthritis severity. The regulatory locus derived from the arthritis-resistant E3 rat strain was introgressed into the arthritis-susceptibility DA strain through
Autor:
Timothy Aitman, Edwin Cuppen, Richard Mott, Alberto Fernandez-Teruel, Adolf Tobena, Ulrika Norin, Sophie Calderari, Toni Cañete Ramirez, Kim Worley, Matthias Heinig, Kathrin Saar, Dominique Gauguier, Tomas Malinauskas, Jonathan Flint, Victor Guryev, Anna Dominiczak
Publikováno v:
Scientific Data
Scientific Data, Nature Publishing Group, 2014, 1, pp.1-14. ⟨10.1038/sdata.2014.11⟩
Scientific Data (1), 1-14. (2014)
Scientific Data, Nature Publishing Group, 2014, 1, pp.1-14. ⟨10.1038/sdata.2014.11⟩
Scientific Data (1), 1-14. (2014)
Membre INSERM du The Rat Genome Sequencing and Mapping Consortium: Sophie Calderari, INSERM, UMRS 872, Centre de Recherche des Cordeliers, Paris, France; International audience; Finding genetic variants that contribute to phenotypic variation is one