Ancestral stories of Ghanaian Bimoba reflect millennia-old genetic lineages.

Autor: Hernando Sanchez-Faddeev, Jeroen Pijpe, David van Bodegom, Tom van der Hulle, Kristiaan J van der Gaag, Ulrika K Eriksson, Thomas Spear, Rudi G J Westendorp, Peter de Knijff

Publikováno v: PLoS ONE, Vol 8, Iss 6, p e65690 (2013)

Oral history and oral genealogies are mechanisms of collective memory and a main cultural heritage of many populations without a writing system. In the effort to analytically address the correspondence between genetic data and historical genealogies,

Externí odkaz: https://doaj.org/article/8174ebe3e3cb42dda49d1e8c8d7a31ad

Genetic variants determining survival and fertility in an adverse African environment: a population-based large-scale candidate gene association study

Autor: Bas J. Zwaan, Jacob J.E. Koopman, P. Eline Slagboom, Rudi G. J. Westendorp, David van Bodegom, Stefan Böhringer, Ulrika K. Eriksson, Peter de Knijff, Juventus B. Ziem, Hernando Sanchez-Faddeev, Jeroen Pijpe

Publikováno v: Aging, 8(7), 1364-1383
Aging 8 (2016) 7
Aging
Aging (Albany NY)
Koopman, J J E, Pijpe, J, Böhringer, S, van Bodegom, D, Eriksson, U K, Sanchez-Faddeev, H, Ziem, J B, Zwaan, B, Slagboom, P E, de Knijff, P & Westendorp, R G J 2016, ' Genetic variants determining survival and fertility in an adverse African environment : a population-based large-scale candidate gene association study ', Aging, vol. 8, no. 7, pp. 1364-1383 . https://doi.org/10.18632/aging.100986

Human survival probability and fertility decline strongly with age. These life history traits have been shaped by evolution. However, research has failed to uncover a consistent genetic determination of variation in survival and fertility. As an expl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205583df6f6b54411d085f0e98fa3c27
https://hdl.handle.net/1887/112447

Associations of Gene Sequence Variation and Serum Levels of C-Reactive Protein and Interleukin-6 with Alzheimer's Disease and Dementia

Autor: Margaret Gatz, Chandra A. Reynolds, Ulrika K. Eriksson, Mun-Gwan Hong, Nancy L. Pedersen, Jonathan A. Prince, Paul W. Dickman, Anna M. Bennet

Publikováno v: Journal of Alzheimer's Disease. 23:361-369

Inflammatory mechanisms have been implicated in Alzheimer's disease (AD) and dementia. We therefore sought to study DNA sequence variation and serum levels of the potent inflammatory mediators Interleukin-6 (IL6) and C-reactive protein (CRP) in relat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e286ddaeca2654c35e282d7fbe66ae5
https://doi.org/10.3233/jad-2010-101671

Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk

Autor: Margaret Gatz, Henrik Grönberg, Kaj Blennow, Nancy L. Pedersen, Mun-Gwan Hong, Bo Malmberg, Jonathan A. Prince, Fredrik Wiklund, Stig Berg, Ulrika K. Eriksson, Boo Johansson, Chandra A. Reynolds, Andrey Alexeyenko

Publikováno v: Human Molecular Genetics. 19:2068-2078

We conducted dense linkage disequilibrium (LD) mapping of a series of 25 genes putatively involved in lipid metabolism in 1567 dementia cases [including 1270 with Alzheimer disease (AD)] and 2203 Swedish controls. Across a total of 448 tested genetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b776a31903c31a8a926b627239652141
https://doi.org/10.1093/hmg/ddq079

Interaction between Smoking and Genetic Factors in the Development of Chronic Bronchitis

Autor: Tim Higenbottam, Ulrika K. Eriksson, Maria Gerhardsson de Verdier, Nancy L. Pedersen, Ulf Nihlén, Annica Dominicus, Magnus Dahlbäck, Jenny Hallberg, Magnus Svartengren

Publikováno v: American Journal of Respiratory and Critical Care Medicine. 177:486-490

Rationale: Smoking is a primary risk factor for chronic bronchitis, emphysema, and chronic obstructive pulmonary disease, but since not all smokers develop disease, it has been suggested that some individuals may be more susceptible to exogenous fact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb702d7aa79d0a46c9348e3823bebfdf
https://doi.org/10.1164/rccm.200704-565oc