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pro vyhledávání: '"Ulrika Espefält Westin"'
Publikováno v:
Pharmaceutical Research. 23:565-572
The aim of this study was to quantify the olfactory transfer of morphine to the brain hemispheres by comparing brain tissue and plasma morphine levels after nasal administration with those after intravenous administration. Morphine (1.0 mg/kg body we
Autor:
Elena Piras, Maria Dahlin, Ulrika Bergström, Erik Björk, Björn Jansson, Ulrika Espefält Westin, Eva B. Brittebo
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 24(5)
The aim of this study was to investigate whether morphine can be transferred along the olfactory pathway to the CNS, thereby circumventing the blood-brain barrier, after nasal administration to rodents. Radiolabelled and unlabelled morphine were admi