Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Ulrika, Pettersson"'
Autor:
Hauke Thomsen, Subhayan Chattopadhyay, Niels Weinhold, Pavel Vodicka, Ludmila Vodickova, Per Hoffmann, Markus M. Nöthen, Karl-Heinz Jöckel, Börge Schmidt, Roman Hajek, Göran Hallmans, Ulrika Pettersson-Kymmer, Florentin Späth, Hartmut Goldschmidt, Kari Hemminki, Asta Försti
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Genome-wide association studies (GWASs) based on common single nucleotide polymorphisms (SNPs) have identified several loci associated with the risk of monoclonal gammopathy of unknown significance (MGUS), a precursor condition for multiple
Externí odkaz:
https://doaj.org/article/56d5d5cebeba496e871fe8346df21e90
Autor:
Molly Went, Laura Duran-Lozano, Gisli H. Halldorsson, Andrea Gunnell, Nerea Ugidos-Damboriena, Philip Law, Ludvig Ekdahl, Amit Sud, Gudmar Thorleifsson, Malte Thodberg, Thorunn Olafsdottir, Antton Lamarca-Arrizabalaga, Caterina Cafaro, Abhishek Niroula, Ram Ajore, Aitzkoa Lopez de Lapuente Portilla, Zain Ali, Maroulio Pertesi, Hartmut Goldschmidt, Lilja Stefansdottir, Sigurdur Y. Kristinsson, Simon N. Stacey, Thorvardur J. Love, Saemundur Rognvaldsson, Roman Hajek, Pavel Vodicka, Ulrika Pettersson-Kymmer, Florentin Späth, Carolina Schinke, Frits Van Rhee, Patrick Sulem, Egil Ferkingstad, Grimur Hjorleifsson Eldjarn, Ulf-Henrik Mellqvist, Ingileif Jonsdottir, Gareth Morgan, Pieter Sonneveld, Anders Waage, Niels Weinhold, Hauke Thomsen, Asta Försti, Markus Hansson, Annette Juul-Vangsted, Unnur Thorsteinsdottir, Kari Hemminki, Martin Kaiser, Thorunn Rafnar, Kari Stefansson, Richard Houlston, Björn Nilsson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Multiple myeloma (MM) is an incurable malignancy of plasma cells. Epidemiological studies indicate a substantial heritable component, but the underlying mechanisms remain unclear. Here, in a genome-wide association study totaling 10,906 case
Externí odkaz:
https://doaj.org/article/45458eb3feec4e09b1c186e45ec468d5
Autor:
Alyssa Clay-Gilmour, Subhayan Chattopadhyay, Michelle A. T. Hildebrandt, Hauke Thomsen, Niels Weinhold, Pavel Vodicka, Ludmila Vodickova, Per Hoffmann, Markus M. Nöthen, Karl-Heinz Jöckel, Börge Schmidt, Christian Langer, Roman Hajek, Göran Hallmans, Ulrika Pettersson-Kymmer, Claes Ohlsson, Florentin Späth, Richard Houlston, Hartmut Goldschmidt, Elisabet E. Manasanch, Aaron Norman, Shaji Kumar, S. Vincent Rajkumar, Susan Slager, Asta Försti, Celine M. Vachon, Kari Hemminki
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 4, Pp 1-5 (2022)
Externí odkaz:
https://doaj.org/article/63a0fba1d40f4266ac1d3c263ce9d339
Autor:
Yiheng Chen, Tianyuan Lu, Ulrika Pettersson-Kymmer, Isobel D. Stewart, Guillaume Butler-Laporte, Tomoko Nakanishi, Agustin Cerani, Kevin Y. H. Liang, Satoshi Yoshiji, Julian Daniel Sunday Willett, Chen-Yang Su, Parminder Raina, Celia M. T. Greenwood, Yossi Farjoun, Vincenzo Forgetta, Claudia Langenberg, Sirui Zhou, Claes Ohlsson, J. Brent Richards
Publikováno v:
Nat Genet
Metabolic processes can influence disease risk and provide therapeutic targets. By conducting genome-wide association studies of 1,091 blood metabolites and 309 metabolite ratios, we identified associations with 690 metabolites at 248 loci; and assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2c7e70ee877e96763f6d625a8b5f011
https://doi.org/10.1038/s41588-022-01270-1
https://doi.org/10.1038/s41588-022-01270-1
Autor:
Louise Grahnemo, Anna L Eriksson, Maria Nethander, Robert Johansson, Mattias Lorentzon, Dan Mellström, Ulrika Pettersson-Kymmer, Claes Ohlsson
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism.
Context Hip fractures constitute a major health concern. An adequate supply of amino acids is crucial to ensure optimal acquisition and remodeling of bone. Circulating amino acid levels have been proposed as markers of bone mineral density, but data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3579ae8b95be0866bcce84954bff02c4
https://doi.org/10.1210/clinem/dgad268
https://doi.org/10.1210/clinem/dgad268
Autor:
Paul J Leo, Margaret M Madeleine, Sophia Wang, Stephen M Schwartz, Felicity Newell, Ulrika Pettersson-Kymmer, Kari Hemminki, Goran Hallmans, Sven Tiews, Winfried Steinberg, Janet S Rader, Felipe Castro, Mahboobeh Safaeian, Eduardo L Franco, François Coutlée, Claes Ohlsson, Adrian Cortes, Mhairi Marshall, Pamela Mukhopadhyay, Katie Cremin, Lisa G Johnson, Cornelia L Trimble, Suzanne Garland, Sepehr N Tabrizi, Nicolas Wentzensen, Freddy Sitas, Julian Little, Maggie Cruickshank, Ian H Frazer, Allan Hildesheim, Matthew A Brown
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007257 (2018)
[This corrects the article DOI: 10.1371/journal.pgen.1006866.].
Externí odkaz:
https://doaj.org/article/99b771a9095e452eac8425f775dfb520
Publikováno v:
International Journal of Circumpolar Health, Vol 74, Iss 0, Pp 1-7 (2015)
Background: Even though vitamin D is mainly produced by exposure to sunlight, little is known regarding vitamin D levels in populations living in sub-Arctic areas with little or no daylight during winter. Objective: We describe distributions of vitam
Externí odkaz:
https://doaj.org/article/4d6146efdf9949c6847ad58b60fe6666
Autor:
Paul J Leo, Margaret M Madeleine, Sophia Wang, Stephen M Schwartz, Felicity Newell, Ulrika Pettersson-Kymmer, Kari Hemminki, Goran Hallmans, Sven Tiews, Winfried Steinberg, Janet S Rader, Felipe Castro, Mahboobeh Safaeian, Eduardo L Franco, François Coutlée, Claes Ohlsson, Adrian Cortes, Mhairi Marshall, Pamela Mukhopadhyay, Katie Cremin, Lisa G Johnson, Cornelia L Trimble, Suzanne Garland, Sepehr N Tabrizi, Nicolas Wentzensen, Freddy Sitas, Julian Little, Maggie Cruickshank, Ian H Frazer, Allan Hildesheim, Matthew A Brown
Publikováno v:
PLoS Genetics, Vol 13, Iss 8, p e1006866 (2017)
A small percentage of women with cervical HPV infection progress to cervical neoplasia, and the risk factors determining progression are incompletely understood. We sought to define the genetic loci involved in cervical neoplasia and to assess its he
Externí odkaz:
https://doaj.org/article/9812636b553a40cf9425ba59c8a48318
Autor:
Nikos Papadimitriou, MSc, Dr Konstantinos K Tsilidis, PhD, Philippos Orfanos, PhD, Vassiliki Benetou, MD, Evangelia E Ntzani, PhD, Isabelle Soerjomataram, PhD, Annemarie Künn-Nelen, PhD, Ulrika Pettersson-Kymmer, PhD, Sture Eriksson, PhD, Prof Hermann Brenner, PhD, Ben Schöttker, PhD, Kai-Uwe Saum, PhD, Bernd Holleczek, PhD, Prof Francine D Grodstein, ScD, Diane Feskanich, ScD, Nicola Orsini, PhD, Prof Alicja Wolk, PhD, Andrea Bellavia, PhD, Prof Tom Wilsgaard, PhD, Lone Jørgensen, PhD, Prof Paolo Boffetta, MD, Prof Dimitrios Trichopoulos, PhD, Prof Antonia Trichopoulou, MD
Publikováno v:
The Lancet Public Health, Vol 2, Iss 5, Pp e239-e246 (2017)
Background: No studies have estimated disability-adjusted life-years (DALYs) lost due to hip fractures using real-life follow-up cohort data. We aimed to quantify the burden of disease due to incident hip fracture using DALYs in prospective cohorts i
Externí odkaz:
https://doaj.org/article/af5485d49b36451494ef5eb2810fa10f
Autor:
Maria Nethander, Eivind Coward, Ene Reimann, Louise Grahnemo, Maiken E. Gabrielsen, Carl Wibom, Reedik Mägi, Thomas Funck-Brentano, Mari Hoff, Arnulf Langhammer, Ulrika Pettersson-Kymmer, Kristian Hveem, Claes Ohlsson, Mari Nelis, Lili Milani, Tõnu Esko, Andres Metspalu
Publikováno v:
Cell Reports Medicine
Hip fracture is the clinically most important fracture, but the genetic architecture of hip fracture is unclear. Here, we perform a large-scale hip fracture genome-wide association study meta-analysis and Mendelian randomization study using five coho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce1fc5c711daef9605749ce549e10da9
https://doi.org/10.1016/j.xcrm.2022.100776
https://doi.org/10.1016/j.xcrm.2022.100776