Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ulrich T Hacker"'
Autor:
Oliver Coutelle, Hue‐Tran Hornig‐Do, Axel Witt, Maria Andree, Lars M Schiffmann, Michael Piekarek, Kerstin Brinkmann, Jens M Seeger, Maxim Liwschitz, Satomi Miwa, Michael Hallek, Martin Krönke, Aleksandra Trifunovic, Sabine A Eming, Rudolf J Wiesner, Ulrich T Hacker, Hamid Kashkar
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 5, Pp 624-639 (2014)
Abstract In the normal quiescent vasculature, only 0.01% of endothelial cells (ECs) are proliferating. However, this proportion increases dramatically following the angiogenic switch during tumor growth or wound healing. Recent evidence suggests that
Externí odkaz:
https://doaj.org/article/828c57f592b542438293c1257a5a9937
Autor:
Silvia Catanese, Carl Friedrich Beuchel, Teresa Sawall, Florian Lordick, Rommy Brauer, Markus Scholz, Uta Ceglarek, Ulrich T. Hacker
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 6, Pp 2101-2110 (2021)
Abstract Background Cachexia is characterized by a negative protein and energy balance leading to loss of adipose tissue and muscle mass. Cancer cachexia negatively impacts treatment tolerability and prognosis. Supportive interventions should be init
Externí odkaz:
https://doaj.org/article/a51b21f5efc84809a2f324efa88bf455
Autor:
Ulrich T. Hacker, Dirk Hasenclever, Nicolas Linder, Gertraud Stocker, Hyun‐Cheol Chung, Yoon‐Koo Kang, Markus Moehler, Harald Busse, Florian Lordick
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 1, Pp 135-144 (2020)
Abstract Background Body fat and/or muscle composition influences prognosis in several cancer types. For advanced gastric and gastroesophageal junction cancer, we investigated which body composition parameters carry prognostic information beyond well
Externí odkaz:
https://doaj.org/article/2022d846a371467cbc1247d80ce6e73f
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Cancer remains the second most common cause of death worldwide affecting around 10 million patients every year. Among the therapeutic options, chemotherapeutic drugs are widely used but often associated with side effects. In addition, toxicity agains
Externí odkaz:
https://doaj.org/article/92d156eaea2e41a3abe500f63393b19e
Autor:
Ulrich T. Hacker
Publikováno v:
Molecular Therapy - Methods & Clinical Development. 28:394-395
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a68d2e304b5e4f08468f28b21cc7e4cf
https://doi.org/10.1016/j.omtm.2023.02.009
https://doi.org/10.1016/j.omtm.2023.02.009
Autor:
Kerstin Brinkmann, Paola Zigrino, Axel Witt, Michael Schell, Leena Ackermann, Pia Broxtermann, Stephan Schüll, Maria Andree, Oliver Coutelle, Benjamin Yazdanpanah, Jens Michael Seeger, Daniela Klubertz, Uta Drebber, Ulrich T. Hacker, Martin Krönke, Cornelia Mauch, Thorsten Hoppe, Hamid Kashkar
Publikováno v:
Cell Reports, Vol 3, Iss 3, Pp 881-891 (2013)
The BH3-only protein NOXA represents one of the critical mediators of DNA-damage-induced cell death. In particular, its involvement in cellular responses to cancer chemotherapy is increasingly evident. Here, we identify a strategy of cancer cells to
Externí odkaz:
https://doaj.org/article/fa941ddbd6ea4fb9a312631c8f1e6f2e
Autor:
C. Benedikt Westphalen, Carsten Bokemeyer, Reinhard Büttner, Stefan Fröhling, Verena I. Gaidzik, Hanno Glimm, Ulrich T. Hacker, Volker Heinemann, Anna L. Illert, Ulrich Keilholz, Thomas Kindler, Martin Kirschner, Bastian Schilling, Jens T. Siveke, Thomas Schroeder, Verena Tischler, Sebastian Wagner, Wilko Weichert, Daniel Zips, Sonja Loges, Ralf Bargou (Würzburg), Hendrik Bläker (Leipzig), Melanie Börries (Freiburg), Christian Brandts (Frankfurt), Nikolas von Bubnoff (Lübeck), Melanie Demes (Frankfurt), Alexander Desuki (Mainz), Hartmut Döhner (Ulm), Justus Duyster (Freiburg), Nadine Gaisa (Aachen), Annkristin Heine (Bonn), Christoph Heining (Dresden), Peter Horak (Heidelberg), Ivan Jelas (Berlin), Philipp J. Jost (München), Andreas Jung (München), Thomas Kirchner (München), Frederick Klauschen (Berlin), Simon Kreutzfeldt (Heidelberg), Jörg Kumbrink (München), Volker Kunzmann (Würzburg), Silke Lassmann (Freiburg), Klaus Metzeler (München), Peter Möller (Ulm), Nadina Ortiz-Brüchle (Aachen), Claudia Paret (Mainz), Natalie Pelusi (Bonn), Christoph Peters (Freiburg), Nicole Pfarr (München), Daniela Richter (Dresden), Kristina Riedmann (München), Damian Rieke (Berlin), Christoph Ritzel (Mainz), Dirk Schadendorf (Essen), Hans-Ulrich Schildhaus (Essen), Hubert Schorle (Bonn), Thomas Seufferlein (Ulm), Ronald Simon (Hamburg), Albrecht Stenzinger (Heidelberg), Ghazaleh Tabatabai (Tübingen), Janna-Lisa Velthaus (Hamburg), Martin Werner (Freiburg), Peter J. Wild (Frankfurt), Jürgen Wolf (Köln)
Publikováno v:
European Journal of Cancer. 135:1-7
Precision cancer medicine (PCM) holds great promises to offer more effective therapies to patients based on molecular profiling of their individual tumours. Although the PCM approach seems intuitive, multiple conceptional and structural challenges in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff4f13555d75c8a8b4729bce310670e
https://doi.org/10.1016/j.ejca.2020.04.019
https://doi.org/10.1016/j.ejca.2020.04.019
Autor:
Ulrich T. Hacker
Publikováno v:
Kachexie bei Tumorerkrankungen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e27dc0d5699086c7650d4c69235a8670
https://doi.org/10.1055/a-1074-5036
https://doi.org/10.1055/a-1074-5036
Autor:
Nadja Meumann, Christian Schmithals, Leroy Elenschneider, Tanja Hansen, Asha Balakrishnan, Qingluan Hu, Sebastian Hook, Jessica Schmitz, Jan Hinrich Bräsen, Ann-Christin Franke, Olaniyi Olarewaju, Christina Brandenberger, Steven R. Talbot, Josef Fangmann, Ulrich T. Hacker, Margarete Odenthal, Michael Ott, Albrecht Piiper, Hildegard Büning
Publikováno v:
Cancers, Vol 14, Iss 427, p 427 (2022)
Cancers
Cancers; Volume 14; Issue 2; Pages: 427
Cancers
Cancers; Volume 14; Issue 2; Pages: 427
Simple Summary Gene therapy is a novel approach to treat diseases by introducing corrective genetic information into target cells. Adeno-associated virus vectors are the most frequently applied gene delivery tools for in vivo gene therapy and are als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226ed93f8e0c1c6fa8ad6766d9bd85cf
https://www.mdpi.com/2072-6694/14/2/427
https://www.mdpi.com/2072-6694/14/2/427
Autor:
C. Benedikt Westphalen, Carsten Bokemeyer, Reinhard Büttner, Stefan Fröhling, Verena I. Gaidzik, Hanno Glimm, Ulrich T. Hacker, Volker Heinemann, Anna L. Illert, Ulrich Keilholz, Thomas Kindler, Martin Kirschner, Bastian Schilling, Jens T. Siveke, Thomas Schroeder, Verena Tischler, Sebastian Wagner, Wilko Weichert, Daniel Zips, Sonja Loges, Ralf Bargou (Würzburg), Hendrik Bläker (Leipzig), Melanie Börries (Freiburg), Christian Brandts (Frankfurt), Nikolas von Bubnoff (Freiburg), Melanie Demes (Frankfurt), Alexander Desuki (Mainz), Hartmut Döhner (Ulm), Justus Duyster (Freiburg), Nadine Gaisa (Aachen), Annkristin Heine (Bonn), Christoph Heining (Dresden), Peter Horak (Heidelberg), Ivan Jelas (Berlin), Philipp J. Jost (München), Andreas Jung (München), Thomas Kirchner (München), Frederick Klauschen (Berlin), Simon Kreutzfeldt (Heidelberg), Jörg Kumbrink (München), Volker Kunzmann (Würzburg), Silke Lassmann (Freiburg), Klaus Metzeler (München), Peter Möller (Ulm), Nadina Ortiz-Brüchle (Aachen), Claudia Paret (Mainz), Natalie Pelusi (Bonn), Christoph Peters (Freiburg), Nicole Pfarr (München), Daniela Richter (Dresden), Kristina Riedmann (München), Damian Rieke (Berlin), Christoph Ritzel (Mainz), Dirk Schadendorf (Essen), Hans-Ulrich Schildhaus (Essen), Hubert Schorle (Bonn), Thomas Seufferlein (Ulm), Ronald Simon (Hamburg), Albrecht Stenzinger (Heidelberg), Ghazaleh Tabatabai (Tübingen), Janna-Lisa Velthaus (Hamburg), Martin Werner (Freiburg), Peter J. Wild (Frankfurt), Jürgen Wolf (Köln)
Publikováno v:
European Journal of Cancer. 162:245-246
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bde745959fddd05b69fde9954d0a435
https://doi.org/10.1016/j.ejca.2021.11.014
https://doi.org/10.1016/j.ejca.2021.11.014