Zobrazeno 1 - 10
of 759
pro vyhledávání: '"Ulrich Spengler"'
Autor:
Leona Dold, Sandra Kalthoff, Leonie Frank, Taotao Zhou, Pia Esser, Philipp Lutz, Christian P. Strassburg, Ulrich Spengler, Bettina Langhans
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 4, Pp n/a-n/a (2024)
Abstract Introduction Regulatory CD4+ T cells (Tregs) are pivotal for inhibition of autoimmunity. Primary sclerosing cholangitis (PSC) is an autoimmune cholestatic liver disease of unknown etiology where contribution of Tregs is still unclear. Activa
Externí odkaz:
https://doaj.org/article/7cd084b0cd3e473e8b9e1ed6e1b04526
Autor:
Katharina Stratmann, Songül Aydolmus, Wenyi Gu, Dominik Heling, Ulrich Spengler, Birgit Terjung, Christian P. Strassburg, Richard Vollenberg, Irina Blumenstein, Jonel Trebicka
Publikováno v:
Frontiers in Medicine, Vol 10 (2024)
BackgroundInflammatory bowel diseases (IBDs) are often associated with altered liver function tests (LFTs). There is little data on the relationship between abnormal LFT and IBD. Our study aimed to evaluate the prevalence and etiology of elevated LFT
Externí odkaz:
https://doaj.org/article/af2fdedffa7a4c9aa3f913a8cf7921c1
Autor:
Leona Dold, Mette J. Nielsen, Michael Praktiknjo, Carolynne Schwarze-Zander, Christoph Boesecke, Jan-Christian Wasmuth, Jenny Bischoff, Jürgen Kurt Rockstroh, Morten A. Karsdal, Ulrich Spengler, Jonel Trebicka, Christian P. Strassburg, Diana J. Leeming, Bettina Langhans
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background and aims Liver-associated complications still frequently lead to mortality in people with HIV (PWH), even though combined antiretroviral treatment (cART) has significantly improved overall survival. The quantification of circulati
Externí odkaz:
https://doaj.org/article/a44fd9ba1d1f4da09ed1aa2b27340010
Autor:
Benjamin Krämer, Ansel P. Nalin, Feiyang Ma, Sarah Eickhoff, Philipp Lutz, Sonia Leonardelli, Felix Goeser, Claudia Finnemann, Gudrun Hack, Jan Raabe, Michael ToVinh, Sarah Ahmad, Christoph Hoffmeister, Kim M. Kaiser, Steffen Manekeller, Vittorio Branchi, Tobias Bald, Michael Hölzel, Robert Hüneburg, Hans Dieter Nischalke, Alexander Semaan, Bettina Langhans, Dominik J. Kaczmarek, Brooke Benner, Matthew R. Lordo, Jesse Kowalski, Adam Gerhardt, Jörg Timm, Marieta Toma, Raphael Mohr, Andreas Türler, Arthur Charpentier, Tobias van Bremen, Georg Feldmann, Arne Sattler, Katja Kotsch, Ali T. Abdallah, Christian P. Strassburg, Ulrich Spengler, William E. Carson, III, Bethany L. Mundy-Bosse, Matteo Pellegrini, Timothy E. O’Sullivan, Aharon G. Freud, Jacob Nattermann
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111937- (2023)
Summary: Group 1 innate lymphoid cells (ILCs) comprise a heterogeneous family of cytotoxic natural killer (NK) cells and ILC1s. We identify a population of “liver-type” ILC1s with transcriptional, phenotypic, and functional features distinct from
Externí odkaz:
https://doaj.org/article/0084e5451ed64fc0b420c8bfd7ffa888
Autor:
Johannes Chang, Avend Bamarni, Nina Böhling, Xin Zhou, Leah‐Marie Klein, Jonathan Meinke, Georg Daniel Duerr, Philipp Lingohr, Sven Wehner, Maximilian J. Brol, Jürgen K. Rockstroh, Jörg C. Kalff, Steffen Manekeller, Carsten Meyer, Ulrich Spengler, Christian Jansen, Vicente Arroyo, Christian P. Strassburg, Jonel Trebicka, Michael Praktiknjo
Publikováno v:
Hepatology Communications, Vol 5, Iss 7, Pp 1265-1277 (2021)
Acute‐on‐chronic liver failure (ACLF) is a syndrome associated with organ failure and high short‐term mortality. Presence of ACLF at interventions, such as surgery or transjugular intrahepatic portosystemic shunt (TIPS), has been shown to deter
Externí odkaz:
https://doaj.org/article/5b91741d9a9940339cdad0507adc6a62
Publikováno v:
Clinical Case Reports, Vol 10, Iss 3, Pp n/a-n/a (2022)
Abstract Extrahepatic manifestations of chronic hepatitis C virus (HCV) infection frequently involve the skin. Here, we report the case of a woman, who experienced a psoriasis exacerbation on DAA treatment, which lead to psoriasis resolution upon HCV
Externí odkaz:
https://doaj.org/article/8b2c48f8ae2d47788f3c78aff759eaae
Autor:
Christian Liedtke, Yulia A. Nevzorova, Tom Luedde, Henning Zimmermann, Daniela Kroy, Pavel Strnad, Marie-Luise Berres, Jürgen Bernhagen, Frank Tacke, Jacob Nattermann, Ulrich Spengler, Tilman Sauerbruch, Alexander Wree, Zeinab Abdullah, René H. Tolba, Jonel Trebicka, Twan Lammers, Christian Trautwein, Ralf Weiskirchen
Publikováno v:
Frontiers in Medicine, Vol 8 (2022)
The Transregional Collaborative Research Center “Organ Fibrosis: From Mechanisms of Injury to Modulation of Disease” (referred to as SFB/TRR57) was funded for 13 years (2009–2021) by the German Research Council (DFG). This consortium was hosted
Externí odkaz:
https://doaj.org/article/854f4678a7ef45078def2dc8a24e231a
Autor:
Leona Dold, Philipp Lutz, Annkristin Heine, Tobias J. Weismüller, Christian P. Strassburg, Ulrich Spengler
Publikováno v:
Clinical Case Reports, Vol 9, Iss 9, Pp n/a-n/a (2021)
Abstract Although ruxolitinib contributes to immunomodulation and can lead to severe infections, it seems a feasible treatment strategy for patients with polycythemia vera and myelofibrosis after liver transplantation.
Externí odkaz:
https://doaj.org/article/950b4f597cba45e4a07428708f28af56
Autor:
Philipp Lutz, Hannah C. Jeffery, Nicholas Jones, Jane Birtwistle, Benjamin Kramer, Jacob Nattermann, Ulrich Spengler, Christian P. Strassburg, David H. Adams, Ye H. Oo
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background and Aims: Ascites and spontaneous bacterial peritonitis (SBP) are frequent complications of liver cirrhosis. In spite of the clinical impact, knowledge about ascites as an immune cell compartment in liver disease is limited. Therefore, we
Externí odkaz:
https://doaj.org/article/edfa5d89f86d4f1f89fe184d014aae3f
Autor:
Khaled Thabet, Anastasia Asimakopoulos, Maryam Shojaei, Manuel Romero-Gomez, Alessandra Mangia, William L. Irving, Thomas Berg, Gregory J. Dore, Henning Grønbæk, David Sheridan, Maria Lorena Abate, Elisabetta Bugianesi, Martin Weltman, Lindsay Mollison, Wendy Cheng, Stephen Riordan, Janett Fischer, Ulrich Spengler, Jacob Nattermann, Ahmed Wahid, Angela Rojas, Rose White, Mark W. Douglas, Duncan McLeod, Elizabeth Powell, Christopher Liddle, David van der Poorten, Jacob George, Mohammed Eslam, International Liver Disease Genetics Consortium
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Chronic Hepatitis C infection is associated with a broad spectrum of liver pathologies, ranging from inflammation to fibrosis and liver cancer. Here Thabet et al. identified a polymorphism in the gene MBOAT7 that is associated with increased hepatic
Externí odkaz:
https://doaj.org/article/040377325d9345739aef54ce9c9e39f4