Zobrazeno 1 - 10
of 400
pro vyhledávání: '"Ulrich Specks"'
Autor:
Despina Michailidou, Bhargavi Duvvuri, Runa Kuley, David Cuthbertson, Peter C. Grayson, Nader A. Khalidi, Curry L. Koening, Carol A. Langford, Carol A. McAlear, Larry W. Moreland, Christian Pagnoux, Philip Seo, Ulrich Specks, Antoine G. Sreih, Kenneth J. Warrington, Tomas Mustelin, Paul A. Monach, Peter A. Merkel, Christian Lood
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-10 (2022)
Abstract Objective To assess markers of neutrophil activation such as calprotectin and N-formyl methionine (fMET) in anti-neutrophil cytoplasmic autoantibody-associated vasculitis (AAV) and large-vessel vasculitis (LVV). Methods Levels of fMET, and c
Externí odkaz:
https://doaj.org/article/4d4ff93e6b7146b1804cbd57bf2f0bc4
Autor:
John H Stone, Peter C Grayson, Ulrich Specks, E William St Clair, Peter A Merkel, Philip Seo, Carol A Langford, Paul A Monach, Cees G M Kallenberg, Robert F Spiera, Fernando C Fervenza, Zuoming Deng, Wei Tew, Marta Casal Moura, Stephen R Brooks, Marco Prunotto
Publikováno v:
RMD Open, Vol 9, Iss 1 (2023)
Background The frequency of proteinase 3 gene (PRTN3) polymorphisms in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is not fully characterised. We hypothesise that the presence of a PRTN3 gene polymorphism (sin
Externí odkaz:
https://doaj.org/article/6bc5f2edf8284a2885c3e9a25bbce574
Autor:
Paul A. Monach, Roscoe L. Warner, Robert Lew, Gunnar Tómasson, Ulrich Specks, John H. Stone, Fernando C. Fervenza, Gary S. Hoffman, Cees G. M. Kallenberg, Carol A. Langford, Philip Seo, E. William St. Clair, Robert Spiera, Kent J. Johnson, Peter A. Merkel
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 2, Pp 168-176 (2022)
Objective Improved biomarkers of current disease activity and prediction of relapse are needed in antineutrophil cytoplasmic antibody–associated vasculitis (AAV). For clinical relevance, biomarkers must perform well longitudinally in patients on tr
Externí odkaz:
https://doaj.org/article/1b4d66b46e4b402cb73650c340d67054
Autor:
David Jayne, Michael Walsh, Peter A Merkel, Chen Au Peh, Wladimir Szpirt, Xavier Puéchal, Shouichi Fujimoto, Carmel Hawley, Nader Khalidi, Rachel Jones, Oliver Flossmann, Ron Wald, Louis Girard, Adeera Levin, Gina Gregorini, Lorraine Harper, William Clark, Christian Pagnoux, Ulrich Specks, Lucy Smyth, Toshiko Ito-Ihara, Janak de Zoysa, Biljana Brezina, Andrea Mazzetti, Carol A McAlear, Donna Reidlinger, Samir Mehta, Natalie Ives, Elizabeth A Brettell, Hugh Jarrett, Keith Wheatley, Elizabeth Broadhurst, Alina Casian, Charles D Pusey
Publikováno v:
Health Technology Assessment, Vol 26, Iss 38 (2022)
Background: Anti-neutrophil cytoplasm antibody-associated vasculitis is a multisystem, autoimmune disease that causes organ failure and death. Physical removal of pathogenic autoantibodies by plasma exchange is recommended for severe presentations, a
Externí odkaz:
https://doaj.org/article/d0a874aa7a77433586be6d35e45e9780
Autor:
Irena Doubelt, David Cuthbertson, Simon Carette, Sharon A. Chung, Lindsy J. Forbess, Nader A. Khalidi, Curry L. Koening, Carol Langford, Carol A. McAlear, Larry W. Moreland, Paul A. Monach, Philip Seo, Ulrich Specks, Robert F. Spiera, Jason M. Springer, Antoine G. Sreih, Kenneth J. Warrington, Peter A. Merkel, Christian Pagnoux, the Vasculitis Clinical Research Consortium
Publikováno v:
ACR Open Rheumatology, Vol 3, Iss 6, Pp 404-412 (2021)
Objective To describe clinical manifestations and outcomes in patients with eosinophilic granulomatosis with polyangiitis (EGPA) in North America. Methods Analysis of patients aged 18 years or older who fulfilled the 1990 American College of Rheumato
Externí odkaz:
https://doaj.org/article/82128a1fdc6e4dcaa4108c0e269815ce
Autor:
Irena Doubelt, Jason M Springer, Tanaz A Kermani, Antoine G Sreih, Cristina Burroughs, David Cuthbertson, Simon Carette, Nader A Khalidi, Curry L Koening, Carol Langford, Carol A McAlear, Larry W Moreland, Paul A Monach, Dianne G Shaw, Philip Seo, Ulrich Specks, Kenneth J Warrington, Kalen Young, Peter A Merkel, Christian Pagnoux
Publikováno v:
Interactive Journal of Medical Research, Vol 11, Iss 1, p e27273 (2022)
BackgroundPatient-based registries can help advance research on rare diseases such as eosinophilic granulomatosis with polyangiitis (EGPA), a complex multiorgan form of antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis. ObjectiveThe
Externí odkaz:
https://doaj.org/article/56119628cf6c4a39a62f8ed95e17f3cc
Autor:
Jamie R. Felzer, Delvise T. Fogwe, Shaher Samrah, Clement J. Michet Jr, Ulrich Specks, Misbah Baqir, Aahd F. Kubbara
Publikováno v:
Respirology Case Reports, Vol 10, Iss 1, Pp n/a-n/a (2022)
Abstract Inflammatory processes, such as an infection or drug reaction, can cause antineutrophil cytoplasmic autoantibody (ANCA)‐associated vasculitis (AAV). Although quite rare, AAV may occur with SARS‐coronavirus disease 2019 (COVID‐19) antig
Externí odkaz:
https://doaj.org/article/c30b3d63a27e42db9dcb60d75783e8fc
Autor:
Paige K. Marty, Virginia P. Van Keulen, Courtney L. Erskine, Maleeha Shah, Amber Hummel, Michael Stachowitz, Samantha Fatis, Dane Granger, Matthew S. Block, Alí Duarte-García, Kenneth J. Warrington, Elitza S. Theel, Xian Zhou, Hu Zeng, Ulrich Specks, Patricio Escalante, Tobias Peikert
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Humoral vaccine responses are known to be suboptimal in patients receiving B-cell targeted therapy, and little is known about vaccine induced T-cell immunity in these patients. In this study, we characterized humoral and cellular antigen-specific ant
Externí odkaz:
https://doaj.org/article/d90f575f1fbd43b5bd5b27a01dda881f
Autor:
Alvise Berti, Sophie Hillion, Amber M. Hummel, Young Min Son, Nedra Chriti, Tobias Peikert, Eva M. Carmona, Wayel H. Abdulahad, Peter Heeringa, Kristina M. Harris, E. William St. Clair, Paul Brunetta, Fernando C. Fervenza, Carol A. Langford, Cees G.M. Kallenberg, Peter A. Merkel, Paul A. Monach, Philip Seo, Robert F. Spiera, John H. Stone, Guido Grandi, Jie Sun, Jacques-Olivier Pers, Ulrich Specks, Divi Cornec, for the RAVE-ITN Research Group
Publikováno v:
JCI Insight, Vol 6, Iss 22 (2021)
BACKGROUND Little is known about the autoreactive B cells in antineutrophil cytoplasmic antibody–associated (ANCA-associated) vasculitis (AAV). We aimed to investigate tolerance checkpoints of circulating antigen-specific proteinase 3–reactive (P
Externí odkaz:
https://doaj.org/article/17108e393aed484eae0eb4f26d7643a8
Autor:
Kirill Lipatov, Aahd F. Kubbara, Laura E. Weerheim, Dante N. Schiavo, Ulrich Specks, Jay H. Ryu, Misbah Baqir
Publikováno v:
Respiratory Medicine Case Reports, Vol 33, Iss , Pp 101432- (2021)
Constrictive bronchiolitis is one of the manifestations of small-airway involvement in primary Sjögren syndrome (SS) and is associated with fixed airflow obstruction despite treatment with bronchodilators, macrolides, corticosteroids, and corticoste
Externí odkaz:
https://doaj.org/article/1ee974f84df04e41b25860a599fdd34f