Zobrazeno 1 - 10
of 492
pro vyhledávání: '"Ulrich Sommer"'
Autor:
Michael Rade, Markus Kreuz, Angelika Borkowetz, Ulrich Sommer, Conny Blumert, Susanne Füssel, Catharina Bertram, Dennis Löffler, Dominik J. Otto, Livia A. Wöller, Carolin Schimmelpfennig, Ulrike Köhl, Ann-Cathrin Gottschling, Pia Hönscheid, Gustavo B. Baretton, Manfred Wirth, Christian Thomas, Friedemann Horn, Kristin Reiche
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-20 (2024)
Abstract Background Clinical manifestation of prostate cancer (PCa) is highly variable. Aggressive tumors require radical treatment while clinically non-significant ones may be suitable for active surveillance. We previously developed the prognostic
Externí odkaz:
https://doaj.org/article/c464d6da04a84fa9b2ebac3773083177
Autor:
Sherif Mehralivand, Christian Thomas, Martin Puhr, Frank Claessens, Arjanneke F. van de Merbel, Anna Dubrovska, Guido Jenster, Christof Bernemann, Ulrich Sommer, Holger H. H. Erb
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-8 (2024)
Abstract The androgen receptor (AR) is a crucial player in various aspects of male reproduction and has been associated with the development and progression of prostate cancer (PCa). Therefore, the protein is the linchpin of current PCa therapies. De
Externí odkaz:
https://doaj.org/article/2100acb6c028487ea1592470d98b2707
Autor:
Carla Steinhauser, Abdulbaki Yakac, Wenke Markgraf, Susanne Kromnik, Andreas Döcke, Philipp Talhofer, Christine Thiele, Hagen Malberg, Ulrich Sommer, Gustavo B. Baretton, Susanne Füssel, Christian Thomas, Juliane Putz
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10280 (2024)
To identify potentially transplantable organs in a pool of marginal kidneys, 33 porcine slaughterhouse kidneys were perfused for 4 h with whole blood. During the normothermic perfusion, plasma, urine, and tissue samples were taken. Several biomarkers
Externí odkaz:
https://doaj.org/article/c73fc617c70642a284a71df3afb2cf30
Autor:
Luise Rupp, Ina Dietsche, Maximilian Kießler, Ulrich Sommer, Alexander Muckenhuber, Katja Steiger, Casper W. F. van Eijck, Leonard Richter, Rouzanna Istvanffy, Carsten Jäger, Helmut Friess, Casper H. J. van Eijck, Ihsan Ekin Demir, Carmen Mota Reyes, Marc Schmitz
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is typically diagnosed at advanced stages and associated with early distant metastasis and poor survival. Besides clinical factors, the tumor microenvironment (TME) emerged as a crucial determinant of patient s
Externí odkaz:
https://doaj.org/article/060c11c0f0df4fe48ce6b5de61634e0a
Publikováno v:
Frontiers in Marine Science, Vol 11 (2024)
Despite management efforts, anthropogenic nutrient enrichments continue to enhance phytoplankton blooms worldwide. Release of nitrogen and phosphorus compounds not only provides surplus of nutrients but also disbalances their stoichiometry. Declines
Externí odkaz:
https://doaj.org/article/a67a4faddc4e4497a0199b01682b235c
Autor:
Carolin Schimmelpfennig, Michael Rade, Susanne Füssel, Dennis Löffler, Conny Blumert, Catharina Bertram, Angelika Borkowetz, Dominik J. Otto, Sven-Holger Puppel, Pia Hönscheid, Ulrich Sommer, Gustavo B. Baretton, Ulrike Köhl, Manfred Wirth, Christian Thomas, Friedemann Horn, Markus Kreuz, Kristin Reiche
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-20 (2023)
Abstract Background Prostate cancer (PCa) is one of the most prevalent cancers worldwide. The clinical manifestations and molecular characteristics of PCa are highly variable. Aggressive types require radical treatment, whereas indolent ones may be s
Externí odkaz:
https://doaj.org/article/33f9e042a8f748879f7f4908f10f205d
Autor:
Benjamin Terfa Igbo, Annett Linge, Susanne Frosch, Theresa Suckert, Liane Stolz-Kieslich, Steffen Löck, Mani Sankari Kumaravadivel, Thilo Welsch, Jürgen Weitz, Ulrich Sommer, Daniela Aust, Esther G.C. Troost
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 36, Iss , Pp 106-112 (2022)
Background: The microscopic tumor extension before, during or after radiochemotherapy (RCHT) and its correlation with the tumor microenvironment (TME) are presently unknown. This information is, however, crucial in the era of image-guided, adaptive h
Externí odkaz:
https://doaj.org/article/05538a565f874080808ebfc63005fccf
Autor:
Tiziana Siciliano, Ulrich Sommer, Alicia-Marie K. Beier, Matthias B. Stope, Angelika Borkowetz, Christian Thomas, Holger H. H. Erb
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 2, Pp 597-608 (2022)
The androgen receptor (AR) plays a central role in prostate, muscle, bone and adipose tissue. Moreover, dysregulated AR activity is a driving force in prostate cancer (PCa) initiation and progression. Consequently, antagonizing AR signalling cascades
Externí odkaz:
https://doaj.org/article/5eaa04aaad0f464fbc66e7cdf5778420
Autor:
Sebastian Hoberück, Steffen Löck, Angelika Borkowetz, Ulrich Sommer, Robert Winzer, Klaus Zöphel, Dieter Fedders, Enrico Michler, Jörg Kotzerke, Klaus Kopka, Tobias Hölscher, Anja Braune
Publikováno v:
EJNMMI Research, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Background The analysis aimed to compare the radiotracers [68Ga]-Ga-PSMA-11 and [18F]-F-PSMA-1007 intraindividually in terms of malignant lesions, mi(molecular-imaging)TNM staging and presumable unspecific lesions retrospectively as used in
Externí odkaz:
https://doaj.org/article/53864545597b4172b705f82e1ed381d1
Autor:
Max Heiduk, Ioana Plesca, Jessica Glück, Luise Müller, David Digomann, Charlotte Reiche, Janusz von Renesse, Rahel Decker, Christoph Kahlert, Ulrich Sommer, Daniela E. Aust, Marc Schmitz, Jürgen Weitz, Lena Seifert, Adrian M. Seifert
Publikováno v:
JCI Insight, Vol 7, Iss 22 (2022)
BACKGROUND Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis. At diagnosis, only 20% of patients with PDAC are eligible for primary resection. Neoadjuvant chemotherapy can enable surgical resection in 30%–40% of patients with locally a
Externí odkaz:
https://doaj.org/article/9a5a29027fcc4aadb45aea3cef95ab9a