Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ulrich Schuller"'
Autor:
Jelena Rascon, Renata Blackute, Alma Cerkauskiene, Sabine Taschner-Mandl, Nuno Andrade, Adriana Planinic, Stefan Rutkowski, Ulrich Schuller, Karsten Nysom, Ruta Tuckuviene, Jesper Brok, Kjeld Schmiegelow, Marry M. van den Heuvel-Eibrink, M.E. Madeleine van der Perk, Riccardo Haupt, Monica Muraca, Davide Saraceno, Birgit Geoerger, Giorgia Manuzi, Ruth Ladenstein
Publikováno v:
EJC Paediatric Oncology, Vol 3, Iss , Pp 100153- (2024)
Inequalities in research and innovations affect childhood cancer survival across Europe. Vilnius University Hospital Santaros Klinikos (VULSK, the coordinator) and eight research-intensive institutions from seven European countries implemented the TR
Externí odkaz:
https://doaj.org/article/60514195038c4ebba5a83f379381f1cc
Autor:
T. Elise Potthoff, Carolin Walter, Daniela Jeising, Daniel Münter, Archana Verma, Eric Suero Molina, Walter Stummer, Martin Dugas, Wolfgang Hartmann, Matthias Dottermusch, Lea Altendorf, Ulrich Schüller, Sophia Scheuermann, Christian Seitz, Thomas K. Albert, Kornelius Kerl
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Pituitary neuroendocrine tumors (PitNET) are among the most common intracranial tumors. Despite a frequent benign course, aggressive behavior can occur. Tumor behavior is known to be under the influence of the tumor microenvironme
Externí odkaz:
https://doaj.org/article/9d87dc91d88548038291cde05a5e76b8
Autor:
Anja Fischer, Thomas K. Albert, Natalia Moreno, Marta Interlandi, Jana Mormann, Selina Glaser, Paurnima Patil, Flavia W. de Faria, Mathis Richter, Archana Verma, Sebastian T. Balbach, Rabea Wagener, Susanne Bens, Sonja Dahlum, Carolin Göbel, Daniel Münter, Clara Inserte, Monika Graf, Eva Kremer, Viktoria Melcher, Gioia Di Stefano, Raffaella Santi, Alexander Chan, Ahmet Dogan, Jonathan Bush, Martin Hasselblatt, Sylvia Cheng, Signe Spetalen, Alexander Fosså, Wolfgang Hartmann, Heidi Herbrüggen, Stella Robert, Florian Oyen, Martin Dugas, Carolin Walter, Sarah Sandmann, Julian Varghese, Claudia Rossig, Ulrich Schüller, Alexandar Tzankov, Martin B. Pedersen, Francesco A. d’Amore, Karin Mellgren, Udo Kontny, Venkatesh Kancherla, Luis Veloza, Edoardo Missiaglia, Virginie Fataccioli, Philippe Gaulard, Birgit Burkhardt, Oliver Soehnlein, Wolfram Klapper, Laurence de Leval, Reiner Siebert, Kornelius Kerl
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) is a heterogeneous group of malignancies with poor outcome. Here, we identify a subgroup, PTCL-NOS SMARCB1- , which is characterized by the lack of the SMARCB1 protein and occurs
Externí odkaz:
https://doaj.org/article/f9838f5a5f15480799585f8fa2420a7e
Autor:
Shweta Godbole, Hannah Voß, Antonia Gocke, Simon Schlumbohm, Yannis Schumann, Bojia Peng, Martin Mynarek, Stefan Rutkowski, Matthias Dottermusch, Mario M. Dorostkar, Andrey Korshunov, Thomas Mair, Stefan M. Pfister, Marcel Kwiatkowski, Madlen Hotze, Philipp Neumann, Christian Hartmann, Joachim Weis, Friederike Liesche-Starnecker, Yudong Guan, Manuela Moritz, Bente Siebels, Nina Struve, Hartmut Schlüter, Ulrich Schüller, Christoph Krisp, Julia E. Neumann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Medulloblastomas (MBs) are malignant pediatric brain tumors that are molecularly and clinically heterogenous. The application of omics technologies—mainly studying nucleic acids—has significantly improved MB classification and stratifica
Externí odkaz:
https://doaj.org/article/675fc26a61af443188a119d2062987c2
Autor:
Anna, Borgenvik, Karl O, Holmberg, Sara, Bolin, Miao, Zhao, Vasil, Savov, Gabriela, Rosén, Sonja, Hutter, Alexandra, Garancher, Aldwin, Suryo Rahmanto, Tobias, Bergström, Thale Kristin, Olsen, Oliver J, Mainwaring, Damiana, Sattanino, Annemieke D, Verbaan, Jessica M, Rusert, Anders, Sundstrom, Mar, Ballester Bravo, Yonglong, Dang, Amelie S, Wenz, Stacey, Richardson, Grammatiki, Fotaki, Rebecca M, Hill, Adrian M, Dubuc, Antonia, Kalushkova, Marc, Remke, Matko, Cancer, Helena, Jernberg-Wiklund, Géraldine, Giraud, Xingqi, Chen, Michael D, Taylor, Olle, Sangfelt, Steven C, Clifford, Ulrich, Schuller, Robert J, Wechsler-Reya, Holger, Weishaupt, Fredrik J, Swartling
Relapse is the leading cause of death in patients with medulloblas-toma, the most common malignant pediatric brain tumor. A better understanding of the mechanisms underlying recurrence could lead to more effective therapies for targeting tumor relaps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1824f3a53174e63398f529f085bb4e59
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-494638
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-494638
Autor:
Jürgen Hench, Claus Hultschig, Jon Brugger, Luigi Mariani, Raphael Guzman, Jehuda Soleman, Severina Leu, Miles Benton, Irenäus Maria Stec, Ivana Bratic Hench, Per Hoffmann, Patrick Harter, Katharina J Weber, Anne Albers, Christian Thomas, Martin Hasselblatt, Ulrich Schüller, Lisa Restelli, David Capper, Ekkehard Hewer, Joachim Diebold, Danijela Kolenc, Ulf C. Schneider, Elisabeth Rushing, Rosa della Monica, Lorenzo Chiariotti, Martin Sill, Daniel Schrimpf, Andreas von Deimling, Felix Sahm, Christian Kölsche, Markus Tolnay, Stephan Frank
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract DNA methylation analysis based on supervised machine learning algorithms with static reference data, allowing diagnostic tumour typing with unprecedented precision, has quickly become a new standard of care. Whereas genome-wide diagnostic me
Externí odkaz:
https://doaj.org/article/0728b5481b5942bf8a38046de711832e
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Immunologic treatment options are uncommon in low-grade gliomas, although such therapies might be beneficial for inoperable and aggressive cases. Knowledge of the immune and stromal cells in low-grade gliomas is highly relevant for such approaches bu
Externí odkaz:
https://doaj.org/article/0183920c352f4aceb07c5120e8b40e65
Autor:
Richard Drexler, Florian Brembach, Jennifer Sauvigny, Franz L. Ricklefs, Alicia Eckhardt, Helena Bode, Jens Gempt, Katrin Lamszus, Manfred Westphal, Ulrich Schüller, Malte Mohme
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-8 (2024)
Abstract DNA methylation analysis has become a powerful tool in neuropathology. Although DNA methylation-based classification usually shows high accuracy, certain samples cannot be classified and remain clinically challenging. We aimed to gain insigh
Externí odkaz:
https://doaj.org/article/148f558c75074ac9829fbfc45b1d8605
Autor:
Carolin Göbel, Shweta Godbole, Melanie Schoof, Dörthe Holdhof, Catena Kresbach, Carolin Loose, Julia Neumann, Ulrich Schüller
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-13 (2023)
Abstract Group 3 medulloblastoma is one of the most aggressive types of childhood brain tumors. Roughly 30% of cases carry genetic alterations in MYC, SMARCA4, or both genes combined. While overexpression of MYC has previously been shown to drive med
Externí odkaz:
https://doaj.org/article/234db635bc2b43d68c70869f656e3164
Autor:
Melanie Schoof, Shweta Godbole, Thomas K. Albert, Matthias Dottermusch, Carolin Walter, Annika Ballast, Nan Qin, Marlena Baca Olivera, Carolin Göbel, Sina Neyazi, Dörthe Holdhof, Catena Kresbach, Levke-Sophie Peter, Gefion Dorothea Epplen, Vanessa Thaden, Michael Spohn, Mirjam Blattner-Johnson, Franziska Modemann, Martin Mynarek, Stefan Rutkowski, Martin Sill, Julian Varghese, Ann-Kristin Afflerbach, Alicia Eckhardt, Daniel Münter, Archana Verma, Nina Struve, David T. W. Jones, Marc Remke, Julia E. Neumann, Kornelius Kerl, Ulrich Schüller
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Pediatric high-grade gliomas of the subclass MYCN (HGG-MYCN) are highly aggressive tumors frequently carrying MYCN amplifications, TP53 mutations, or both alterations. Due to their rarity, such tumors have only recently been identified as a
Externí odkaz:
https://doaj.org/article/09d9e0ef2e924a438dede74c6b3805ed