Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ulrich Schibler"'
Autor:
Ulrich Schibler, Charna Dibner
Publikováno v:
Acta Physiologica, Vol. 222, No 2 (2018)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::840b24fce324e33a325d6ef4512cdd0b
https://archive-ouverte.unige.ch/unige:103578
https://archive-ouverte.unige.ch/unige:103578
Autor:
Charna Dibner, Ulrich Schibler
Publikováno v:
JOURNAL OF INTERNAL MEDICINE
J Intern Med
Journal of Internal Medicine, Vol. 277, No 5 (2015) pp. 513-27
J Intern Med
Journal of Internal Medicine, Vol. 277, No 5 (2015) pp. 513-27
Most living beings, including humans, must adapt to rhythmically occurring daily changes in their environment that are generated by the Earth's rotation. In the course of evolution, these organisms have acquired an internal circadian timing system th
Autor:
Charna Dibner, Ulrich Schibler
Publikováno v:
Science, Vol. 350, No 6261 (2015) pp. 628-9
SCIENCE
SCIENCE
The circadian timing system plays an essential role in the temporal coordination of metabolism in health and disease ( 1 ). This includes maintaining blood glucose homeostasis, a process that is regulated to a large extent by insulin. Cell-autonomous
Autor:
Edward E. Schmidt, Ulrich Schibler
Publikováno v:
Developmental Biology, Vol. 184, No 1 (1997) pp. 138-149
Early spermatids contain roughly 1000-fold more TATA-binding protein (TBP) mRNA than do somatic cells. The appearance of TBP-overexpressing spermatids in the developing testis is accompanied by a large increase in whole-organ levels of total RNA and
Autor:
Andre Liani, Yann Emmenegger, Camille Saini, Yves Alain Poget, Luigi Bonacina, Florian Kreppel, Ulrich Schibler, Jean-Pierre Wolf, Pascal Gos, Paulus Franken, Thomas Curie
Publikováno v:
Genes and Development, Vol. 27, No 13 (2013) pp. 1526-1536
Genes & Development
Genes & Development
The mammalian circadian timing system consists of a master pacemaker in the suprachiasmatic nucleus (SCN) in the hypothalamus, which is thought to set the phase of slave oscillators in virtually all body cells. However, due to the lack of appropriate
Publikováno v:
Biological Chemistry Hoppe-Seyler, Vol. 377, No 12 (1996) pp. 797-810
PAR and C/EBP family proteins are liver-enriched basic leucine zipper (bZip) transcription factors that bind similar sites on the promoters of albumin and cholesterol 7 alpha hydroxylase genes. However, C/EBP proteins have a more relaxed binding spec
Publikováno v:
Cell, Vol. 83, No 1 (1995) pp. 137-146
The protein kinase MO15/CDK7 has recently been shown to be associated with the general transcription factor TFIIH and to be capable of phosphorylating the RNA polymerase II carboxy-terminal domain. Here, we show that a monoclonal MO15/CDK7 antibody c
Autor:
Ulrich Schibler, Edward E. Schmidt
Publikováno v:
The Journal of Cell Biology, Vol. 128, No 4 (1995) pp. 467-483
The Journal of Cell Biology
The Journal of Cell Biology
Cell sizes can differ vastly between cell types in individual metazoan organisms. In rat liver, spleen, and thymus, differences in average cell size roughly reflect differences in RNA:DNA ratios. For example, hepatocytes were found to have a cytoplas
Publikováno v:
Nucleic Acids Research, Vol. 22, No 5 (1994) pp. 756-766
The efficiency and tissue-specificity of transgene expression in animals is usually subject to the position of integration into the host chromatin. We have discovered that a 2.8kbp fragment flanking the rat gene encoding the transcription factor LAP
Publikováno v:
Proceedings of the National Academy of Sciences, Vol. 90, No 17 (1993) pp. 8219-8223
The CCAAT/enhancer-binding protein (C/EBP) alpha is a leucine zipper protein that is preferentially expressed in certain cell types, such as adipocytes and hepatocytes. Here we show that C/EBP alpha mRNA is translated into two major proteins, C/EBP-4