Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Ulrich Pehl"'
Autor:
Andree Blaukat, Lyubomir T. Vassilev, Beatrix Blume, Thomas Grombacher, Thomas Fuchss, Ulrich Pehl, Heike Dahmen, Li-Ya Chiu, Frank T. Zenke, Astrid Zimmermann
Supplementary Table from A New Class of Selective ATM Inhibitors as Combination Partners of DNA Double-Strand Break Inducing Cancer Therapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d348de2b58e80573a68a640529b1c56
https://doi.org/10.1158/1535-7163.22522248
https://doi.org/10.1158/1535-7163.22522248
Autor:
Andree Blaukat, Lyubomir T. Vassilev, Christiane Amendt, Thomas Fuchss, Claudia Wilm, Thomas Grombacher, Ulrich Pehl, Vladimir Kirkin, Heike Dahmen, Christian Sirrenberg, Astrid Zimmermann, Frank T. Zenke
Physical and chemical DNA-damaging agents are used widely in the treatment of cancer. Double-strand break (DSB) lesions in DNA are the most deleterious form of damage and, if left unrepaired, can effectively kill cancer cells. DNA-dependent protein k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da0e55c5d046814765f05ef007fff9a
https://doi.org/10.1158/1535-7163.c.6542803.v1
https://doi.org/10.1158/1535-7163.c.6542803.v1
Autor:
Andree Blaukat, Lyubomir T. Vassilev, Beatrix Blume, Thomas Grombacher, Thomas Fuchss, Ulrich Pehl, Heike Dahmen, Li-Ya Chiu, Frank T. Zenke, Astrid Zimmermann
Radiotherapy and chemical DNA-damaging agents are among the most widely used classes of cancer therapeutics today. Double-strand breaks (DSB) induced by many of these treatments are lethal to cancer cells if left unrepaired. Ataxia telangiectasia-mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353b2e8d957524d1b5ea6e1e993e5d14
https://doi.org/10.1158/1535-7163.c.6543315.v1
https://doi.org/10.1158/1535-7163.c.6543315.v1
Autor:
Andree Blaukat, Lyubomir T. Vassilev, Christiane Amendt, Thomas Fuchss, Claudia Wilm, Thomas Grombacher, Ulrich Pehl, Vladimir Kirkin, Heike Dahmen, Christian Sirrenberg, Astrid Zimmermann, Frank T. Zenke
Supplementary Table S1: Evaluation of M3814 (MSC2490484) in kinase assays Supplementary Table S2: In vitro activity of M3814 in combination with a single dose of gamma radiation in a panel of 93 cell lines. Supplementary Table S3: Pharmacokinetic dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e3c3f062536172fc64c7760da99e54
https://doi.org/10.1158/1535-7163.22520839
https://doi.org/10.1158/1535-7163.22520839
Autor:
Andree Blaukat, Lyubomir T. Vassilev, Beatrix Blume, Thomas Grombacher, Thomas Fuchss, Ulrich Pehl, Heike Dahmen, Li-Ya Chiu, Frank T. Zenke, Astrid Zimmermann
Supplementary Data from A New Class of Selective ATM Inhibitors as Combination Partners of DNA Double-Strand Break Inducing Cancer Therapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc45d6d8ecdb1a5c73f71289e89a091
https://doi.org/10.1158/1535-7163.22522278.v1
https://doi.org/10.1158/1535-7163.22522278.v1
Autor:
Andree Blaukat, Lyubomir T. Vassilev, Beatrix Blume, Thomas Grombacher, Thomas Fuchss, Ulrich Pehl, Heike Dahmen, Li-Ya Chiu, Frank T. Zenke, Astrid Zimmermann
Supplementary Figure from A New Class of Selective ATM Inhibitors as Combination Partners of DNA Double-Strand Break Inducing Cancer Therapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f1099e6bd81ae07653a34ba19f815e
https://doi.org/10.1158/1535-7163.22522266
https://doi.org/10.1158/1535-7163.22522266
Autor:
Andree Blaukat, Oliver Schadt, Frank Stieber, Ulrich Pehl, Frank Jaehrling, Dieter Dorsch, Michael Meyring, Ulrich Grädler, Claus Fittschen, Claudia Wilm, Christine Knuehl, Manja Friese-Hamim, Bettina Faden, Friedhelm Bladt
PDF file - 75K, High responsiveness of c-Met-addicted cell lines to treatment with EMD 1214063 and EMD 1204831. The impact of EMD 1214063 and EMD 1204831 on tumor cell viability (IC50) was tested in vitro, using a panel of tumor cell lines specifical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19326c3f35618f2086e6990b85bcee69
https://doi.org/10.1158/1078-0432.22451541
https://doi.org/10.1158/1078-0432.22451541
Autor:
Andree Blaukat, Oliver Schadt, Frank Stieber, Ulrich Pehl, Frank Jaehrling, Dieter Dorsch, Michael Meyring, Ulrich Grädler, Claus Fittschen, Claudia Wilm, Christine Knuehl, Manja Friese-Hamim, Bettina Faden, Friedhelm Bladt
PDF file - 184K, EMD 1214063 and EMD 1204831 display anti-tumor activity in HGF-dependent and HGF-independent xenograft tumor models. Mice bearing subcutaneous tumors derived from the human gastric Hs746T cell line (A and B) or the glioblastoma U87MG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03592926e46a69b8ef9743e7c67128ac
https://doi.org/10.1158/1078-0432.22451550
https://doi.org/10.1158/1078-0432.22451550
Autor:
Andree Blaukat, Oliver Schadt, Frank Stieber, Ulrich Pehl, Frank Jaehrling, Dieter Dorsch, Michael Meyring, Ulrich Grädler, Claus Fittschen, Claudia Wilm, Christine Knuehl, Manja Friese-Hamim, Bettina Faden, Friedhelm Bladt
PDF file - 255K, Effective inhibition of in vitro tumor cell migration by EMD 1214063 and EMD 1204831. A classical "wound healing" test was performed to assess the impact of EMD 1214063 (A) and EMD 1204831 (B) on tumor cell migration. In brief, H441
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f477947e78a52a3426f6e533a5fb5e63
https://doi.org/10.1158/1078-0432.22451568
https://doi.org/10.1158/1078-0432.22451568
Autor:
Andree Blaukat, Oliver Schadt, Frank Stieber, Ulrich Pehl, Frank Jaehrling, Dieter Dorsch, Michael Meyring, Ulrich Grädler, Claus Fittschen, Claudia Wilm, Christine Knuehl, Manja Friese-Hamim, Bettina Faden, Friedhelm Bladt
PDF file - 53K, Characteristics of the antibodies used in the study. The specificity, isotype, clone number, and commercial source of the antibodies used throughout the study are indicated. All antibodies were used according to the manufacturer's ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167a2577129d987e5e7e4a54a52b7819
https://doi.org/10.1158/1078-0432.22451544.v1
https://doi.org/10.1158/1078-0432.22451544.v1