Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Ulrich M, Zissler"'
Autor:
Constanze A. Jakwerth, Hannah Kitzberger, Dimitrii Pogorelov, Annika Müller, Simon Blank, Carsten B. Schmidt-Weber, Ulrich M. Zissler
Publikováno v:
Frontiers in Allergy, Vol 3 (2022)
MicroRNAs (miRs) have gained scientific attention due to their importance in the pathophysiology of allergic diseases as well as their potential as biomarkers in allergen-specific treatment options. Their function as post-transcriptional regulators,
Externí odkaz:
https://doaj.org/article/a4cfb817e63a4d98ba32ca3afa20226d
Autor:
Francesca Alessandrini, Renske de Jong, Maria Wimmer, Ann-Marie Maier, Isis Fernandez, Miriam Hils, Jeroen T. Buters, Tilo Biedermann, Ulrich M. Zissler, Christian Hoffmann, Julia Esser-von-Bieren, Carsten B. Schmidt-Weber, Caspar Ohnmacht
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The lung epithelial barrier serves as a guardian towards environmental insults and responds to allergen encounter with a cascade of immune reactions that can possibly lead to inflammation. Whether the environmental sensor aryl hydrocarbon receptor (A
Externí odkaz:
https://doaj.org/article/7125a1b3a8ba42299e74b2e4ca8c349e
Autor:
Stephanie Musiol, Francesca Alessandrini, Constanze A. Jakwerth, Adam M. Chaker, Evelyn Schneider, Ferdinand Guerth, Benjamin Schnautz, Johanna Grosch, Ileana Ghiordanescu, Julia T. Ullmann, Josephine Kau, Mirjam Plaschke, Stefan Haak, Thorsten Buch, Carsten B. Schmidt-Weber, Ulrich M. Zissler
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
TGF-β1 is known to have a pro-inflammatory impact by inducing Th9 and Th17 cells, while it also induces anti-inflammatory Treg cells (Tregs). In the context of allergic airway inflammation (AAI) its dual role can be of critical importance in influen
Externí odkaz:
https://doaj.org/article/2107742a722a4451ab2e2106650214cb
Autor:
Anna Erb, Ulrich M. Zissler, Madlen Oelsner, Adam M. Chaker, Carsten B. Schmidt-Weber, Constanze A. Jakwerth
Publikováno v:
Biosensors, Vol 12, Iss 11, p 929 (2022)
Biosensors such as toll-like receptors (TLR) induce the expression of interferons (IFNs) after viral infection that are critical to the first step in cell-intrinsic host defense mechanisms. Their differential influence on epithelial integrity genes,
Externí odkaz:
https://doaj.org/article/347b9773ae1e4dd7b3c47cbc93dafea7
Autor:
Sonja Heine, Antonio Aguilar-Pimentel, Dennis Russkamp, Francesca Alessandrini, Valerie Gailus-Durner, Helmut Fuchs, Markus Ollert, Reinhard Bredehorst, Caspar Ohnmacht, Ulrich M. Zissler, Martin Hrabě de Angelis, Carsten B. Schmidt-Weber, Simon Blank
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1527 (2022)
Allergen-specific immunotherapy (AIT) is the only currently available curative treatment option for allergic diseases. AIT often includes depot-forming and immunostimulatory adjuvants, to prolong allergen presentation and to improve therapeutic effic
Externí odkaz:
https://doaj.org/article/da0e951d8333498baf33e5d2f9e05ac9
Autor:
Christina Wagner, Karin Uliczka, Judith Bossen, Xiao Niu, Christine Fink, Marcus Thiedmann, Mirjam Knop, Christina Vock, Ahmed Abdelsadik, Ulrich M. Zissler, Kerstin Isermann, Holger Garn, Mario Pieper, Michael Wegmann, Andreas R. Koczulla, Claus F. Vogelmeier, Carsten B. Schmidt-Weber, Heinz Fehrenbach, Peter König, Neil Silverman, Harald Renz, Petra Pfefferle, Holger Heine, Thomas Roeder
Publikováno v:
Cell Reports, Vol 35, Iss 1, Pp 108956- (2021)
Summary: Extensive remodeling of the airways is a major characteristic of chronic inflammatory lung diseases such as asthma or chronic obstructive pulmonary disease (COPD). To elucidate the importance of a deregulated immune response in the airways f
Externí odkaz:
https://doaj.org/article/5354c466531b406f9630e85c7a49e02a
Autor:
Constanze A. Jakwerth, Jose Ordovas-Montanes, Simon Blank, Carsten B. Schmidt-Weber, Ulrich M. Zissler
Publikováno v:
Cells, Vol 11, Iss 9, p 1387 (2022)
The airway epithelium provides the first line of defense to the surrounding environment. However, dysfunctions of this physical barrier are frequently observed in allergic diseases, which are tightly connected with pro- or anti-inflammatory processes
Externí odkaz:
https://doaj.org/article/0aa63b9eb8884d5d95c35bf01ef1c5d0
Autor:
Johannes Grosch, Antoine Lesur, Stéphanie Kler, François Bernardin, Gunnar Dittmar, Elisabetta Francescato, Simon J. Hewings, Constanze A. Jakwerth, Ulrich M. Zissler, Matthew D. Heath, Markus Ollert, Matthias F. Kramer, Christiane Hilger, Maria Beatrice Bilò, Carsten B. Schmidt-Weber, Simon Blank
Publikováno v:
Toxins, Vol 14, Iss 4, p 284 (2022)
Allergy to Polistes dominula (European paper wasp) venom is of particular relevance in Southern Europe, potentially becoming a threat in other regions in the near future, and can be effectively cured by venom immunotherapy (VIT). As allergen content
Externí odkaz:
https://doaj.org/article/9dd7396232544d4c823462a5d47153c8
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The immune response to antigens is a key aspect of immunology, as it provides opportunities for therapeutic intervention. However, the induction of immunological tolerance is an evolving area that is still not sufficiently understood. Allergen immuno
Externí odkaz:
https://doaj.org/article/5370042885e64179ac6c45d0c83d36a1
Autor:
Andreas Frey, Lars P. Lunding, Johanna C. Ehlers, Markus Weckmann, Ulrich M. Zissler, Michael Wegmann
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Allergic bronchial asthma is a chronic disease of the airways that is characterized by symptoms like respiratory distress, chest tightness, wheezing, productive cough, and acute episodes of broncho-obstruction. This symptom-complex arises on the basi
Externí odkaz:
https://doaj.org/article/8286b70aaaf2438caf1182a83bc8d162