Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ulrich Kaeppler"'
Autor:
Christoph Gelhaus, Matthias Leippe, Tanja Schirmeister, Philip J. Rosenthal, Jiri Gut, Gabriele Pradel, Saskia Heppner, Birgit Vedder, Franziska Schulz, Markus Schiller, Monika Herb, Ulrich Kaeppler, Marie-Adrienne Dude
Publikováno v:
Molecules, Vol 14, Iss 1, Pp 19-35 (2008)
A series of etacrynic acid derivatives was synthesized and screened for their in vitro activity against Plasmodium falciparum, as well as their activity against recombinantly expressed falcipain-2 and -3. The two most active compounds of the series d
Externí odkaz:
https://doaj.org/article/4565cec2b0ab47c490c6d71ee08fe49e
Autor:
Monika Herb, Tanja Schirmeister, Matthias Leippe, Ulrich Kaeppler, Philip J. Rosenthal, Markus Schiller, Saskia Heppner, Marie-Adrienne Dude, Franziska Schulz, Gabriele Pradel, Birgit Vedder, Jiri Gut, Christoph Gelhaus
Publikováno v:
Molecules
Molecules; Volume 14; Issue 1; Pages: 19-35
Molecules, Vol 14, Iss 1, Pp 19-35 (2008)
Molecules (Basel, Switzerland), vol 14, iss 1
Molecules; Volume 14; Issue 1; Pages: 19-35
Molecules, Vol 14, Iss 1, Pp 19-35 (2008)
Molecules (Basel, Switzerland), vol 14, iss 1
A series of etacrynic acid derivatives was synthesized and screened for their in vitro activity against Plasmodium falciparum, as well as their activity against recombinantly expressed falcipain-2 and -3. The two most active compounds of the series d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6369972bbb005f61e8590c999da95538
Autor:
Markus Schiller, Daniel Rupprecht, Nikolaus Stiefl, Tanja Schirmeister, Ulrich Kaeppler, Carsten Schmuck, Werner Schmitz, John Ziebuhr, Alexander Breuning, Radim Vicik, Knut Baumann
Publikováno v:
Journal of Medicinal Chemistry. 48:6832-6842
The coronavirus main protease, M(pro), is considered to be a major target for drugs suitable for combating coronavirus infections including severe acute respiratory syndrome (SARS). An HPLC-based screening of electrophilic compounds that was performe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f3fc55560fd043ae659c908b64345b
https://doi.org/10.1021/jm0501782
https://doi.org/10.1021/jm0501782
Autor:
Tanja Schirmeister, Ulrich Kaeppler
Publikováno v:
Medicinal Chemistry. 1:361-370
Cysteine proteases are connected to various viral and parasitic infections, as well as to other severe diseases like arthritis, stroke and cancer. Due to its alpha,beta-unsaturated carbonyl moiety etacrynic acid, a well known diuretic, can inhibit cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::659268f630937c1457eca7debe62a207
https://doi.org/10.2174/1573406054368701
https://doi.org/10.2174/1573406054368701
Autor:
Tanja Schirmeister, Ulrich Kaeppler
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 3:361-373
In comparison to the huge number of peptidic and peptidomimetic inhibitors of cysteine proteases which have been developed during the last twenty years the number of non-peptidic compounds with cysteine protease inhibiting properties is restricted to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023fa2381cad391c33c0cb5014972474
https://doi.org/10.2174/1389557033488079
https://doi.org/10.2174/1389557033488079