Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ulrich Jacquemard"'
Publikováno v:
Synthesis. 2009:759-766
Sphingosine-1-phosphate (S1P, 1) is a bioactive sphingolipid metabolite involved in a variety of critical cellular processes including proliferation, survival, and migration. For this reason the stereoselective syntheses of S1P and analogues are of g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c692cc223204dd8dc0c72764d9c90ac
https://doi.org/10.1055/s-0028-1083373
https://doi.org/10.1055/s-0028-1083373
Autor:
Ulrich Jacquemard, Amélie Lansiaux, Jean-Yves Mérour, Nathalie Dias, Sylvain Routier, Christian Bailly, Jean-François Goossens
Publikováno v:
European Journal of Medicinal Chemistry. 40:1087-1095
A series of 2,5- and 3,5-diphenylpyridine derivatives was synthetised in high yields. A versatile chemical strategy allows the design of diphenylpyridines differently substituted with cationic or neutral side chains. The interaction of the molecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e3d04a959d9c0e2736eb42b0b7d879
https://doi.org/10.1016/j.ejmech.2005.04.011
https://doi.org/10.1016/j.ejmech.2005.04.011
Publikováno v:
Tetrahedron Letters. 54:4793-4795
Highly bulky N,N′-diaryl imidazolinium salts substituted by one or two tert-butyl groups on the heterocyclic backbone and the corresponding silver N-heterocyclic carbene complexes are obtained by the addition of tert-butyl magnesium chloride or ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9757920a006fff33ce01ff048bea59c
https://doi.org/10.1016/j.tetlet.2013.06.132
https://doi.org/10.1016/j.tetlet.2013.06.132
Autor:
Farial Tanious, W. David Wilson, Nathalie Dias, Sylvain Routier, Brigitte Baldeyrou, Christian Bailly, Christelle Tardy, Ulrich Jacquemard, Amélie Lansiaux, Pierre Colson, Jean-Yves Mérour
Publikováno v:
Biochemistry. 43:15169-15178
Double-stranded DNA is a therapeutic target for a variety of anticancer and antimicrobial drugs. Noncovalent interactions of small molecules with DNA usually occur via intercalation of planar compounds between adjacent base pairs or minor-groove reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e24f0071f22364e4733f3aefc4ac206b
https://doi.org/10.1021/bi048474o
https://doi.org/10.1021/bi048474o
Autor:
Gérard Coudert, Sylvain Routier, Myriam Lefoix, Valérie Bénéteau, Ulrich Jacquemard, Jean-Yves Mérour
Publikováno v:
Tetrahedron. 60:10039-10047
A new mild method allowing the removal of carbamates using TBAF in THF is reported. Reactions were performed on indole, indoline, N-methyl aniline, aniline and tryptamine derivatives. The observed selectivity according to the carbamates or the substr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9fc12f7ca93f4e14ff7ac9742fe383
https://doi.org/10.1016/j.tet.2004.07.071
https://doi.org/10.1016/j.tet.2004.07.071
Publikováno v:
European Journal of Inorganic Chemistry. 2002:357-368
Mononuclear and binuclear carbonylruthenium(II) complexes with N2O2 Schiff base ligands based on 3,5-di-tert-butylsalicylaldehyde and three different ortho-diamines have been prepared. The mononuclear Ru(BSP)(CO) [BSP = N,N′-bis(3,5-di-tert-butylsa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b55a9e94dc9701d6f2d6a40927413d18
https://doi.org/10.1002/1099-0682(20022)2002:2<357::aid-ejic357>3.0.co
https://doi.org/10.1002/1099-0682(20022)2002:2<357::aid-ejic357>3.0.co
Publikováno v:
ChemInform. 44
Highly bulky N,N′-diaryl imidazolinium salts substituted by one or two tert-butyl groups on the heterocyclic backbone and the corresponding silver N-heterocyclic carbene complexes are obtained by the addition of tert-butyl magnesium chloride or ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de750067b70fd36a20738db2bdaaf8cc
https://doi.org/10.1002/chin.201352126
https://doi.org/10.1002/chin.201352126
Autor:
Claude Vaccher, Marion Toussaint, Patricia Melnyk, Catherine Foulon, Deborah Mousset, Ulrich Jacquemard
Publikováno v:
ChemInform. 41
Sigma-1 receptors are involved in numerous pathological dysfunctions and the synthesis of selective ligands is of interest. We identified a fused tetrahydroisoquinoline-hydantoin (Tic-hydantoin) structure with high affinity and selectivity for these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d99a028aa9d90a395e9d322f476a061a
https://doi.org/10.1002/chin.201019029
https://doi.org/10.1002/chin.201019029
Autor:
Catherine Foulon, Ulrich Jacquemard, Claude Vaccher, Deborah Mousset, Marion Toussaint, Patricia Melnyk
Publikováno v:
European journal of medicinal chemistry. 45(1)
Sigma-1 receptors are involved in numerous pathological dysfunctions and the synthesis of selective ligands is of interest. We identified a fused tetrahydroisoquinoline-hydantoin (Tic-hydantoin) structure with high affinity and selectivity for these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e027bf6a13684bffc7ce8419717dd109
https://pubmed.ncbi.nlm.nih.gov/19875205
https://pubmed.ncbi.nlm.nih.gov/19875205
Autor:
Amélie Lansiaux, Ulrich Jacquemard, Jean-François Goossens, Christian Bailly, Sylvain Routier, Nathalie Dias, Jean-Yves Mérour, Brigitte Baldeyrou
Publikováno v:
ChemInform. 37
A series of 2,6-diphenylpyrazine derivatives was synthesized from 2,6-dichloropyrazine and 4-methoxyphenylboronic acid using palladium(0) as catalyst in a Suzuki methodology. After deprotection of the hydroxyl, alkylation reactions with different hal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595eea689e0d2d5a8be57c0cee48f361
https://doi.org/10.1002/chin.200617168
https://doi.org/10.1002/chin.200617168