Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Ulrich Hilgenfeldt"'
Publikováno v:
British Journal of Pharmacology. 148:825-832
1 The potential cardioprotective effect of ACE inhibitors has been attributed to the inhibition of bradykinin degradation. Recent data in rats documented a kallidin-like peptide, which mimics the cardioprotective effect of ischaemic preconditioning.
Publikováno v:
British Journal of Pharmacology. 146:958-963
The kallikrein–kinin system is subdivided into the plasma and tissue–kallikrein–kinin system, with bradykinin (BK) and kallidin (KAL) (Lys0-bradykinin) as functional peptides. This occurs in both humans and other mammals. Both peptides are rele
Publikováno v:
British Journal of Pharmacology. 146:952-957
Bradykinin is thought to play a major role among the endogenous cardioprotective candidates of ischaemic preconditioning (IPC). Little attention has been paid to the fact that in the tissue kallidin (KAL), rather than bradykinin might be the physiolo
Autor:
Carsten Tschöpe, Heinz-Peter Schultheiss, Ulrich Hilgenfeldt, Udo Riester, Alexander Reinecke, Kristof Graf, Ulrich Seidl, Thomas Unger
Publikováno v:
International Immunopharmacology. 3:335-344
The present study examined non-insulin-treated streptozotocin (STZ)-induced diabetic rats to determine the role of kinins in diabetic nephropathy. Their involvement in the renoprotective effect of the angiotensin-converting enzyme inhibitor (ACEI) ra
Regulatory effects of salt diet on renal renin–angiotensin–aldosterone, and kallikrein–kinin systems
Publikováno v:
International Immunopharmacology. 2:1975-1980
The interaction of the renin-angiotensin-aldosterone system (RAAS) and the kallikrein-kinin system (KKS) was investigated in rats fed on a low, normal, and high-salt diet for 2 weeks. At the beginning of the second week, either a B2-receptor antagoni
Autor:
Udo Riester, Rainer Birck, Carsten Tschöpe, Peter Rohmeiss, Thomas Kleemann, Ulrich Hilgenfeldt, Fokko J. van der Woude, Claude Braun
Publikováno v:
International Immunopharmacology. 2:1949-1956
The kallikrein–kinin system (KKS) was investigated in autosomal dominant polycystic kidney disease (ADPKD)-affected rats (PKD) and compared to unaffected controls (SD) and 5/6 nephrectomized rats (5/6 Nx). In addition, patients with ADPKD compared
Autor:
Minghuan Yu, Michael Bader, Carsten Tschöpe, V. Gavriluk, Alexander Reinecke, U. Riester, Ulrich Hilgenfeldt, U. Seidl, Peter Gohlke, Eberhard Ritz, João Bosco Pesquero, K. Graf, Thomas Unger
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
A reduction of renal kallikrein has been found in non-insulin-treated diabetic individuals, suggesting that an impaired renal kallikrein-kinin system (KKS) contributes to the development of diabetic nephropathy. We analyzed relevant components of the
Autor:
Alexander Reinecke, Carsten Tschöpe, Vitali Gavriluk, Thomas Unger, Ulrich Seidl, Udo Riester, Eberhard Ritz, Ulrich Hilgenfeldt
Publikováno v:
Immunopharmacology. 33:344-348
The renal kallikrein-kinin system (KKS) was studied in pair-fed streptozotocin (STZ)-induced diabetic rats and compared with age-matched controls. Twelve weeks after STZ injection, rats were normotensive, showed hyperglycemia, proteinuria, polydipsia
Autor:
R. Krattenmacher, A. Walker, Ulrich Hilgenfeldt, Karsten Parczyk, Rudolf Knauthe, K. H. Fritzemeier
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 48:207-214
In the present study effects of estrogens (natural estradiol and synthetic ethinyl estradiol) on liver derived proteins (angiotensinogen, IGF-I) were investigated in vivo in ovariectomized rats and in vitro in a rat hepatoma cell line (Fe33). The aim
Autor:
Sylvia Schwind, Ulrich Hilgenfeldt
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 45:41-47
The study investigates the change in angiotensinogen (Aogen), angiotensin I (AngI) and renin plasma concentration after nephrectomy and adrenalectomy. The aim of the study was to elucidate the mechanisms that are involved in the up regulation of the