Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Ulrich Grandel"'
Autor:
E. Dikomey, Fabian Eberle, Werner Seeger, Rita Engenhart-Cabillic, Friedrich Grimminger, Florian H. Leinberger, Florentine S.B. Subtil, Gabriele Dahlem, Katja Hattar, Mira Y. Gökyildirim, Elena Schuetz, Ulf Sibelius, Ulrich Grandel
Publikováno v:
Oncotarget
Non-small cell lung cancer (NSCLC) has a very poor prognosis even when treated with the best therapies available today often including radiation. NSCLC is frequently complicated by pulmonary infections which appear to impair prognosis as well as ther
Autor:
Ulrich Grandel, MY Gökyildirim, Werner Seeger, Katja Hattar, F Grimminger, Ulf Sibelius, Rita Engenhart-Cabillic, Fsb Subtil
Publikováno v:
Herbsttagung der Sektionen Zellbiologie und Infektiologie und Tuberkulose der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e.V..
Autor:
Katja Hattar, Ulrich Grandel, Ulf Sibelius, Ralph T. Schermuly, F. Grimminger, Norbert Weissmann, R.M. Bohle, S Oppermann, C. Ankele, B. Krögel, Werner Seeger, R Moritz
Publikováno v:
European Respiratory Journal. 36:187-195
Anti-neutrophil cytoplasmic antibodies (c-ANCA) targeting proteinase 3 (PR3) are implicated in the pathogenesis of Wegener's granulomatosis (WG). Fulminant disease can present as acute lung injury (ALI). In this study, a model of ALI in WG was develo
Autor:
Katja Hattar, Werner Seeger, Ulrich Grandel, Stefanie Sigel, Ulf Sibelius, Friedrich Grimminger, Ludger Fink, Diana Heygster
Publikováno v:
Molecular Cancer Research. 7:1729-1735
Proinflammatory cytokines are centrally involved in tumor progression and survival in non–small cell lung cancer, and both the presence of infiltrating neutrophils and bacterial infection in the lung may indicate a poor prognosis. Against this back
Autor:
Michael Buerke, Hendrik Schmidt, Ulrich Grandel, Justin M. Carter, Ulf Sibelius, Ute Buerke, Karl Werdan, Werner Seeger, Friedrich Grimminger, Axel Schlitt, Martin Russ, Ursula Mueller-Werdan
Publikováno v:
Shock. 29:497-503
Bacterial toxins cause cardiac dysfunction and death through an inflammatory process, but the mechanism remains unclear. Simvastatin is recognized as having anti-inflammatory properties beyond its lipid-lowering effects. We examined Staphylococcus au
Autor:
Friedrich Grimminger, Alexander Moeller, Ulf Sibelius, Katja Hattar, Siegfried Morath, Ludger Fink, Julia Iglhaut, Werner Seeger, Thomas Hartung, Ulrich Grandel
Publikováno v:
Critical Care Medicine. 34:835-841
Objective In sepsis, Gram-positive and Gram-negative bacteria provoke similar inflammatory processes. Whereas lipopolysaccharides (LPSs) are acknowledged as the principal immunostimulatory components of Gram-negative bacteria, the effect of the Gram-
Autor:
Friedrich Grimminger, Ulf Sibelius, Michael Buerke, Ladislau Kiss, Werner Seeger, Ulrich Grandel, Martina Heep, Konstantin Mayer, Katja Hattar, Robin Benkelmann
Publikováno v:
Critical Care Medicine. 34:118-126
Objective: Staphylococcal α-toxin and Escherichia coli hemolysin (ECH) evoke cardiac dysfunction in isolated rat hearts by provoking myocardial synthesis of arachidonic acid-derived thromboxane A 2 or the cysteinyl-leukotrienes, LTC 4 , LTD 4 , and
Autor:
Friedrich Grimminger, Elena Csernok, Sandra van Bürck, U. Maus, Ulrich Grandel, Ulf Sibelius, Thomas Hartung, Jürgen Lohmeyer, Werner Seeger, Annette Bickenbach, Katja Hattar
Publikováno v:
Journal of Leukocyte Biology. 78:992-1000
In Wegener's granulomatosis (WG), a pathogenetic role has been proposed for circulating anti-neutrophil-cytoplasmic antibodies (ANCA) targeting proteinase 3 (PR3). Disease activation in WG appears to be triggered by bacterial infections. In the prese
Autor:
Ute Buerke, Ulrich Grandel, Roland Prondzinsky, Karl Werdan, Werner Seeger, Hendrik Schmidt, F. Grimminger, M. Ruß, Ulf Sibelius, Michael Buerke
Publikováno v:
Intensivmedizin + Notfallmedizin. 42:156-164
Simvastatin, ein HMG-CoA-Reduktase-Inhibitor, wird im klinischen Alltag zur Senkung des Cholesterin-Spiegels eingesetzt. Daruber hinaus berichteten aktuelle Studien uber protektive Eigenschaften von Statinen unter inflammatorischen Bedingungen. In di
Autor:
Diethard Pruefer, Friedrich Grimminger, Hellmut Oelert, Michael Buerke, Manfred Dahm, Ulf Sibelius, Jürgen Meyer, Ulrich Grandel, Harald Darius, W Seeger, Ute Buerke, Joachim Makowski, Martin Schnell
Publikováno v:
Circulation. 106:2104-2110
Background—Simvastatin, a 3-hydroxy-methylglutaryl coenzyme A reductase inhibitor, has been shown to lower serum cholesterol levels in clinical use. Moreover, statins exert beneficial effects in vascular diseases by inhibition of leukocyte rolling,