Výsledky vyhledávání - "Ulrich Furrer"

Dynamics of Aβ Turnover and Deposition in Different β-Amyloid Precursor Protein Transgenic Mouse Models Following γ-Secretase Inhibition

Autor: Julia Reichwald, Dieter Staab, Matthias Staufenbiel, Domenico Ammaturo, Marie-Josephine Runser, Markus Stoeckli, Karl-Heinz Wiederhold, Ulrich Furrer, Anton Neuenschwander, Simone Danner, Anne-Lise Jaton, Ulf Neumann, Dorothee Abramowski, Heinrich Rueeger

Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 327:411-424

Human beta-amyloid precursor protein (APP) transgenic mice are commonly used to test potential therapeutics for Alzheimer's disease. We have characterized the dynamics of beta-amyloid (Abeta) generation and deposition following gamma-secretase inhibi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1849a85bb7feb92e5418ae37a984390d
https://doi.org/10.1124/jpet.108.140327

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P2-064 Rapid Aβ turnover and reduction of amyloid plaque formation after acute and long-term inhibition of Aβ generation in APP23 mice

Autor: Heinrich Rueeger, Robert Holloway, Claudia Mistl, Dorothee Abramowski, Karl-Heinz Wiederhold, Anton Neuenschwander, Anne-Lise Jaton, Matthias Staufenbiel, Jean-Marie Vigouret, Ulrich Furrer

Publikováno v: Neurobiology of Aging. 25:S242

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b7395e529cd6a68bdebc5897e807d4fb
https://doi.org/10.1016/s0197-4580(04)80811-x

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