Alignment of stroma fibers, microvessel density and immune cell populations determine overall survival in pancreatic cancer-An analysis of stromal morphology.

Autor: Louisa Bolm, Petro Zghurskyi, Hryhoriy Lapshyn, Ekaterina Petrova, Sergiy Zemskov, Yogesh K Vashist, Steffen Deichmann, Kim C Honselmann, Peter Bronsert, Tobias Keck, Ulrich F Wellner

Publikováno v: PLoS ONE, Vol 15, Iss 7, p e0234568 (2020)

IntroductionThe aim of this study was to define histo-morphological stroma characteristics by analyzing stromal components, and to evaluate their impact on local and systemic tumor spread and overall survival in pancreatic ductal adenocarcinoma (PDAC

Externí odkaz: https://doaj.org/article/ade6be108c0840948f2536c71cd106c1

Minimally invasive versus open distal pancreatectomy for resectable pancreatic cancer (DIPLOMA): an international randomised non-inferiority trialResearch in context

Autor: Maarten Korrel, Leia R. Jones, Jony van Hilst, Gianpaolo Balzano, Bergthor Björnsson, Ugo Boggi, Svein Olav Bratlie, Olivier R. Busch, Giovanni Butturini, Giovanni Capretti, Riccardo Casadei, Bjørn Edwin, Anouk M.L.H. Emmen, Alessandro Esposito, Massimo Falconi, Bas Groot Koerkamp, Tobias Keck, Ruben H.J. de Kleine, Dyre B. Kleive, Arto Kokkola, Daan J. Lips, Sanne Lof, Misha D.P. Luyer, Alberto Manzoni, Ravi Marudanayagam, Matteo de Pastena, Nicolò Pecorelli, John N. Primrose, Claudio Ricci, Roberto Salvia, Per Sandström, Frederique L.I.M. Vissers, Ulrich F. Wellner, Alessandro Zerbi, Marcel G.W. Dijkgraaf, Marc G. Besselink, Mohammad Abu Hilal, Adnan Alseidi, Constanza Aquilano, Johanna Arola, Denise Bianchi, Rachel Brown, Daniela Campani, Joanne ChinAleong, Jerome Cros, Lyubomira Dimitrova, Claudio Doglioni, Safi Dokmak, Russell Dorer, Michael Doukas, Jean Michel Fabre, Giovanni Ferrari, Viacheslay Grinevich, Stefano Gobbo, Thilo Hackert, Marius van den Heuvel, Clement Huijsentruijt, Mar Iglesias, Casper Jansen, Igor Khatkov, David Kooby, Marco Lena, Claudio Luchini, Krishna Menon, Patrick Michenet, Quintus Molenaar, Anna Nedkova, Andrea Pietrabissa, Mihaela Raicu, Rushda Rajak, Branislava Rankovic, Aniko Rendek, Benjamin Riviere, Antonio Sa Cunha, Olivier Saint Marc, Patricia Sanchez Velazquez, Donatella Santini, Aldo Scarpa, Mylene Sebagh, Donald Sears, Mihir Shah, Zahir Soonawalla, Paola Spaggiari, Lars Tharun, Tore Tholfsen, Ales Tomazic, Alessandro Vanoli, Caroline Verbeke, Joanne Verheij, Moritz Von Winterfeld, Roeland de Wilde, Vincent Yip, Yoh Zen

Publikováno v: The Lancet Regional Health. Europe, Vol 31, Iss , Pp 100673- (2023)

Summary: Background: The oncological safety of minimally invasive surgery has been questioned for several abdominal cancers. Concerns also exist regarding the use of minimally invasive distal pancreatectomy (MIDP) in patients with resectable pancreat

Externí odkaz: https://doaj.org/article/bcb4c761ba7445f683cf39084a0f3045

The pancreatic surgery registry (StuDoQ|Pancreas) of the German Society for General and Visceral Surgery (DGAV) – presentation and systematic quality evaluation

Autor: Ulrich F. Wellner, Carsten Klinger, Kai Lehmann, Heinz Buhr, Edmund Neugebauer, Tobias Keck

Publikováno v: Trials, Vol 18, Iss 1, Pp 1-9 (2017)

Abstract Background Pancreatic resections are among the most complex procedures in visceral surgery. While mortality has decreased substantially over the past decades, morbidity remains high. The volume-outcome correlation in pancreatic surgery is am

Externí odkaz: https://doaj.org/article/6b5d2f374aba49d780341b5a68fffcc0

Learning curve of three European centers in laparoscopic, hybrid laparoscopic, and robotic pancreatoduodenectomy

Autor: Tobias Keck, Magomet Baychorov, P. Tyutyunnik, Ugo Boggi, Hryhoriy Lapshyn, Francesca Menonna, Ulrich F. Wellner, Sjors Klompmaker, Mark G. Besselink, Abe Fingerhut, Igor Khatkov, Moh'd Abu Hilal, Carlo Lombardo, Roman Izrailov, Niccolò Napoli

Publikováno v: Surgical endoscopy, 36(2), 1515-1526. Springer New York

Introduction: There are limited numbers of high-volume centers performing minimally invasive pancreatoduodenectomy (MIPD) routinely. Several approaches to MIPD have been described. Aim of this analysis was to show the learning curve of three differen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7345196dda15c5820e9d06892dd8b7c
https://doi.org/10.1007/s00464-021-08439-5

Kidney Transplantation after Extended Multivisceral Resection for Pancreatic Ductal Adenocarcinoma

Autor: Hryhoriy Lapshyn, Louisa Bolm, Martin Nitschke, Andreas M. Luebke, Jakob R. Izbicki, Yogesh K. Vashist, Tobias Keck, Ulrich F. Wellner

Publikováno v: Case Reports in Transplantation, Vol 2018 (2018)

Long-term survival in patients with pancreatic ductal adenocarcinoma (PDAC) is limited. Consequently, solid organ transplantation in PDAC patients is usually not considered. This is the first case report of kidney transplantation (KT) in a 57-year-ol

Externí odkaz: https://doaj.org/article/e0b5a07d7203496a903cceb0729ca438