Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ulrich Brauns"'
Autor:
Syed Nabeel-Shah, Shuye Pu, Giovanni L. Burke, Nujhat Ahmed, Ulrich Braunschweig, Shaghayegh Farhangmehr, Hyunmin Lee, Mingkun Wu, Zuyao Ni, Hua Tang, Guoqing Zhong, Edyta Marcon, Zhaolei Zhang, Benjamin J. Blencowe, Jack F. Greenblatt
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-34 (2024)
Abstract Background N6-methyladenosine (m6A), the most abundant internal modification on eukaryotic mRNA, and N6, 2′-O-dimethyladenosine (m6Am), are epitranscriptomic marks that function in multiple aspects of posttranscriptional regulation. Fat ma
Externí odkaz:
https://doaj.org/article/4328bd3f4ab2479fba71d2541dde57fd
Autor:
Andrew J. Best, Ulrich Braunschweig, Mingkun Wu, Shaghayegh Farhangmehr, Adrian Pasculescu, Justin J. Lim, Lim Caden Comsa, Mark Jen, Jenny Wang, Alessandro Datti, Jeffrey L. Wrana, Sabine P. Cordes, Rima Al-awar, Hong Han, Benjamin J. Blencowe
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Disruption of alternative splicing frequently causes or contributes to human diseases and disorders. Consequently, there is a need for efficient and sensitive reporter assays capable of screening chemical libraries for compounds with efficac
Externí odkaz:
https://doaj.org/article/bdd3329af36c492bb7c45d82dc1c1b13
Autor:
Edmund Kostewicz, Robert Becker, Martin Wunderlich, Jennifer B. Dressman, Ulrich Brauns, Thomas Bock
Publikováno v:
Journal of Pharmacy and Pharmacology. 56:43-51
Solubility and dissolution relationships in the gastrointestinal tract can be critical for the oral bioavailability of poorly soluble drugs. In the case of poorly soluble weak bases, the possibility of drug precipitation upon entry into the small int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e130a43495ed4fa62f7f6c2cc6fe831
https://doi.org/10.1211/0022357022511
https://doi.org/10.1211/0022357022511
Publikováno v:
Pharmaceutical Research. 19:345-349
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29a65ddd69ea8607e821b6d4f1d3478e
https://doi.org/10.1023/a:1014407421366
https://doi.org/10.1023/a:1014407421366
Autor:
Katherine Chan, Adrian Granda Farias, Hunsang Lee, Furkan Guvenc, Patricia Mero, Kevin R. Brown, Henry Ward, Maximilian Billmann, Kamaldeep Aulakh, Audrey Astori, Shahan Haider, Edyta Marcon, Ulrich Braunschweig, Shuye Pu, Andrea Habsid, Amy Hin Yan Tong, Natasha Christie-Holmes, Patrick Budylowski, Ayoob Ghalami, Samira Mubareka, Finlay Maguire, Arinjay Banerjee, Karen L. Mossman, Jack Greenblatt, Scott D. Gray-Owen, Brian Raught, Benjamin J. Blencowe, Mikko Taipale, Chad Myers, Jason Moffat
Publikováno v:
Heliyon, Vol 9, Iss 1, Pp e12744- (2023)
SARS-CoV-2 depends on host cell components for infection and replication. Identification of virus-host dependencies offers an effective way to elucidate mechanisms involved in viral infection and replication. If druggable, host factor dependencies ma
Externí odkaz:
https://doaj.org/article/1fc0974096af4f23af93d99b3d0085a0
Autor:
Gabrijela Dumbović, Ulrich Braunschweig, Heera K. Langner, Michael Smallegan, Josep Biayna, Evan P. Hass, Katarzyna Jastrzebska, Benjamin Blencowe, Thomas R. Cech, Marvin H. Caruthers, John L. Rinn
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
RNA localization plays an important role in transcriptome regulation. The majority of TERT transcripts are detected in the nucleus and TUG1 lncRNAs in both the nucleus and cytoplasm. Here, the authors combine single-cell RNA imaging, antisense oligon
Externí odkaz:
https://doaj.org/article/0a69eec1edfb49478cd0ef2274c07334
Autor:
Marie-Ming Aynaud, J. Javier Hernandez, Seda Barutcu, Ulrich Braunschweig, Kin Chan, Joel D. Pearson, Daniel Trcka, Suzanna L. Prosser, Jaeyoun Kim, Miriam Barrios-Rodiles, Mark Jen, Siyuan Song, Jess Shen, Christine Bruce, Bryn Hazlett, Susan Poutanen, Liliana Attisano, Rod Bremner, Benjamin J. Blencowe, Tony Mazzulli, Hong Han, Laurence Pelletier, Jeffrey L. Wrana
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Wide-spread outbreaks of pathogens require high intensity testing to manage. Here, the authors present C19-SPAR-Seq, a scalable and automated platform to analyse tens of thousands of SARS-CoV-2 patient samples in a single run.
Externí odkaz:
https://doaj.org/article/ac044901fa7a4d629bfedd519a0399c2
Publikováno v:
Pharmaceutical research. 19(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf8a350a5abb01f9e43efdd1e6d33c47
https://pubmed.ncbi.nlm.nih.gov/11934243
https://pubmed.ncbi.nlm.nih.gov/11934243
Autor:
Syed Nabeel-Shah, Hyunmin Lee, Nujhat Ahmed, Giovanni L. Burke, Shaghayegh Farhangmehr, Kanwal Ashraf, Shuye Pu, Ulrich Braunschweig, Guoqing Zhong, Hong Wei, Hua Tang, Jianyi Yang, Edyta Marcon, Benjamin J. Blencowe, Zhaolei Zhang, Jack F. Greenblatt
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103562- (2022)
Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein is essential for viral replication, making it a promising target for antiviral drug and vaccine development. SARS-CoV-2 infected patients exhibit an uncoor
Externí odkaz:
https://doaj.org/article/71c0d267688a465ca9051e412cc3eba6
Autor:
Gabrijela Dumbović, Ulrich Braunschweig, Heera K. Langner, Michael Smallegan, Josep Biayna, Evan P. Hass, Katarzyna Jastrzebska, Benjamin Blencowe, Thomas R. Cech, Marvin H. Caruthers, John L. Rinn
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/f1914cc10d7442a8ae60fc72d2d25477