Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Ulrich Bolder"'
Publikováno v:
Langenbeck's Archives of Surgery. 394:331-337
Soft tissue sarcomas (STS) are rare tumors. General treatment is difficult while multimodality treatment strategies are more and more common. In these strategies, surgical resection of the primary tumor is essential to achieve local control of the tu
Autor:
Hans-Jürgen Schlitt, Karl-Walter Jauch, Thomas S. Weiss, Wolfgang E. Thasler, Marc G. Jeschke, Dagmar Klein, Ulrich Bolder
Publikováno v:
Molecular Medicine. 14:11-19
Hepatic homeostasis is essential for survival in critically ill and burned patients. Insulin administration improves survival and decreases infections in these patients. To determine the molecular mechanisms, the aim of the present study was to estab
Autor:
Christoph E. Heyde, Marc G. Jeschke, Wolfgang Ertel, David N. Herndon, Martin Haslbeck, Rene Przkora, Ulrich Bolder
Publikováno v:
Burns. 33:628-633
Background Hepatic failure following sepsis is one of the important features of burns. Studies have shown that in septic rats, heat stress (HS) has a protective effect on bile acid transporters in hepatocyte membranes. This study investigates the inf
Autor:
Gudrun E. Koehl, Ferdinand Hofstaedter, Lee M. Ellis, Ulrike Seidel, Edward K. Geissler, Frauke Bataille, Ulrich Bolder, Andreas Gaumann, Sven A. Lang, Hans J. Schlitt, Oliver Stoeltzing, Dagmar Klein
Publikováno v:
International Journal of Cancer. 120:1803-1810
The mammalian target of rapamycin (mTOR) has become an interesting target for cancer therapy through its influence on oncogenic signals, which involve phosphatidylinositol-3-kinase and hypoxia-inducible factor-1α (HIF-1α). Since mTOR is an upstream
Autor:
Marc G. Jeschke, David N. Herndon, Ulla Müller, Steven E. Wolf, Ulrich Bolder, James C. Thompson, Celeste C. Finnerty, Rene Przkora, Rainer Maihöfer
Publikováno v:
Surgery. 138:482-489
A severe burn injury is associated with an impairment of gut mucosal integrity and function, which is due to increases in small-bowel epithelial cell apoptosis and decreases in cell proliferation. Hepatocyte growth factor (HGF) was shown to improve r
Autor:
Ulrich Bolder, Slawo Sirek, Karl-Walter Jauch, Edward K. Geissler, Igors Iesalnieks, Kerstin Puellmann, Thomas Mueller, A. Beham, Markus Rentsch, K. Kienle
Publikováno v:
Transplant International. 18:1079-1089
Inhibition or destruction of Kupffer cells (KC) may protect against ischemia-reperfusion (IR) induced primary graft noiilunction (PNF) in liver transplantation. Besides KC activation, PNF is characterized by microvascular perfusion failure, intrahepa
Publikováno v:
Shock. 20:536-543
Inflammation and catabolism in response to trauma, surgery, critical illness or bacteria lead to a compromise of essential organs, which can lead to prolonged clinical stay and even death. Mediators responsible for catabolism were thought to be proin
Autor:
Frauke Bataille, H. Wagner, A. Reichle, H. Messmann, Ferdinand Hofstädter, Karl-Walter Jauch, Peter J. Wild, Reinhard Andreesen, Ulrich Bolder, Matthias Zaiss
Publikováno v:
Bone Marrow Transplantation. 32:665-671
The present multimodal treatment approach was designed to achieve prolonged tumor control in advanced gastric cancer. A total of 26 patients with stage IV gastric cancer (metastatic disease n=25), ECOG performance status 0-3 and laparoscopically eval
Publikováno v:
Journal of Parenteral and Enteral Nutrition. 24:140-144
Recombinant human growth hormone (rhGH) promotes protein synthesis, accelerates wound healing, and maintains immune function in the catabolic state. It has also been claimed that rhGH may promote the activation of residual tumor cells, and therefore,
Autor:
Ulrich Bolder, R P Elferink, M. J. Kothe, Piter J. Bosma, Coen C. Paulusma, Guido N. J. Tytgat, Irene van Bokhoven, Conny T. Bakker, Jan van Marle
Publikováno v:
Hepatology (Baltimore, Md.), 31(3), 684-693. John Wiley and Sons Ltd
We have studied regulation of the multidrug resistance protein 2 (mrp2) during bile duct ligation (BDL) in the rat. In hepatocytes isolated after 16, 48, and 72 hours of BDL, mrp2-mediated dinitrophenyl-glutathione (DNP-GS) transport was decreased to