Zobrazeno 1 - 10
of 339
pro vyhledávání: '"Ulrich BLANK"'
Autor:
John TCHEN, Quentin SIMON, Léa CHAPART, Morgane K. THAMINY, Shamila VIBHUSHAN, Loredana SAVEANU, Yasmine LAMRI, Fanny SAIDOUNE, Emeline PACREAU, Christophe PELLEFIGUES, Julie BEX-COUDRAT, Hajime KARASUYAMA, Kensuke MIYAKE, Juan HIDALGO, Padraic G. FALLON, Thomas PAPO, Ulrich BLANK, Marc BENHAMOU, Guillaume HANOUNA, Karim SACRE, Eric DAUGAS, Nicolas CHARLES
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by anti-nuclear autoantibodies whose production is promoted by autoreactive T follicular helper (TFH) cells. During SLE pathogenesis, basophils accumulate in secondary
Externí odkaz:
https://doaj.org/article/2b261c12033c4401a2b53ad4f143bfa7
Autor:
Ulrich Blank, Carlo Pucillo
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/d4484c7281b74d1e824505e9a32d7aa0
Autor:
Manuela Bratti, Shamila Vibhushan, Cyril Longé, Despoina Koumantou, Gaël Ménasché, Marc Benhamou, Nadine Varin-Blank, Ulrich Blank, Loredana Saveanu, Sanae Ben Mkaddem
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The function of intracellular trafficking in immune-complex triggered inflammation remains poorly understood. Here, we investigated the role of Insulin-Regulated Amino Peptidase (IRAP)-positive endosomal compartments in Fc receptor (FcR)-induced infl
Externí odkaz:
https://doaj.org/article/3faaf41d039145589aa4626bfa0fc628
Autor:
John Tchen, Quentin Simon, Léa Chapart, Christophe Pellefigues, Hajime Karasuyama, Kensuke Miyake, Ulrich Blank, Marc Benhamou, Eric Daugas, Nicolas Charles
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tissue-specific mouse models are essential tools to decipher the role of each cell compartment and/or their expressed genes in the pathophysiology of diseases. Here, we describe a new knock-in mouse model allowing expression of both the fluorescent p
Externí odkaz:
https://doaj.org/article/6d84a6fd725646d891b31d23a059b29f
Publikováno v:
Zeitschrift für Parlamentsfragen, 1970 Dec 01. 1(4), 486-486.
Externí odkaz:
https://www.jstor.org/stable/24195957
Publikováno v:
Cells, Vol 11, Iss 19, p 3055 (2022)
Mast cells (MCs) are well-known for their role in IgE-mediated cutaneous anaphylactic responses, but their regulatory functions in the skin are still under intense scrutiny. Using a Red MC and Basophil reporter (RMB) mouse allowing red fluorescent de
Externí odkaz:
https://doaj.org/article/2e970a965f8b4e9c880b7ae1a14c2fc6
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mast cells are well known for their role in allergies and many chronic inflammatory diseases. They release upon stimulation, e.g., via the IgE receptor, numerous bioactive compounds from cytoplasmic secretory granules. The regulation of granule secre
Externí odkaz:
https://doaj.org/article/83abfccbec5241f4a35db98b73103e3a
Autor:
Cyril Longé, Manuela Bratti, Mathieu Kurowska, Shamila Vibhushan, Pierre David, Valère Desmeure, Jian-Dong Huang, Alain Fischer, Geneviève de Saint Basile, Fernando E. Sepulveda, Ulrich Blank, Gaël Ménasché
Publikováno v:
Journal of Allergy and Clinical Immunology. 150:676-689
Mast cells (MCs) are key effectors of the allergic response. Following the cross-linking of IgE receptors (FcεRIs), they release crucial inflammatory mediators through degranulation. Although degranulation depends critically on secretory granule (SG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389839c1bb4f842b6b3bccdfd5ac2987
https://doi.org/10.1016/j.jaci.2022.04.009
https://doi.org/10.1016/j.jaci.2022.04.009
Autor:
Sanae Ben Mkaddem, Amaya Murua, Héloise Flament, Dimitri Titeca-Beauport, Carine Bounaix, Luca Danelli, Pierre Launay, Marc Benhamou, Ulrich Blank, Eric Daugas, Nicolas Charles, Renato C. Monteiro
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Src-family kinases Fyn and Lyn are signaling components downstream of ITAM-bearing antigen receptors. Here the authors show that by phosphorylating SHP-1 at different residues, Lyn and Fyn can have opposing regulatory effects on ITAM receptors.
Externí odkaz:
https://doaj.org/article/018c8dd96b534ef981f995c3443a4374
Autor:
Carlo E. Pucillo, Mario P. Colombo, Ulrich Blank, Alice Rigoni, Stefania Marzinotto, Laura Mariuzzi, Claudio Tripodo, Lucia Bongiovanni, Carla Guarnotta, Francesca Mion, Giorgia Gri, Barbara Frossi, Luca Danelli
Inflammation plays crucial roles at different stages of tumor development and may lead to the failure of immune surveillance and immunotherapy. Myeloid-derived suppressor cells (MDSC) are one of the major components of the immune-suppressive network
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58e7c46ec87c334fcf1bc76b1f1c20b0
https://doi.org/10.1158/2326-6066.c.6548417.v1
https://doi.org/10.1158/2326-6066.c.6548417.v1
