Zobrazeno 1 - 10
of 561 408
pro vyhledávání: '"Ulrich A."'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Assessment of lung function is an important clinical tool for the diagnosis and monitoring of chronic lung diseases, including idiopathic pulmonary fibrosis (IPF). In mice, lung function maneuvers use algorithm-based ventilation strategies i
Externí odkaz:
https://doaj.org/article/df22953c84d64e2fac490c68944354ee
Autor:
Leo Caratsch, Christian Lechtenboehmer, Matteo Caorsi, Karine Oung, Fabio Zanchi, Yasser Aleman, Ulrich A. Walker, Patrick Omoumi, Thomas Hügle
Publikováno v:
ACR Open Rheumatology, Vol 6, Iss 6, Pp 388-395 (2024)
Objective Automated machine learning (autoML) platforms allow health care professionals to play an active role in the development of machine learning (ML) algorithms according to scientific or clinical needs. The aim of this study was to develop and
Externí odkaz:
https://doaj.org/article/30f088bae7454825b1e5aad93ca5cafc
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-8 (2024)
Abstract Objectives Neutrophil extracellular trap formation and cell-free DNA (cfDNA) contribute to the inflammation in rheumatoid arthritis (RA), but it is unknown if mitochondrial DNA (mtDNA) or nuclear DNA (nDNA) is more abundant in the circulatio
Externí odkaz:
https://doaj.org/article/b8584ee576c0402fb711de3ac0777148
Autor:
Franziska Roeder, Tina Röpke, Lara-Kristin Steinmetz, Martin Kolb, Ulrich A. Maus, Bradford J. Smith, Lars Knudsen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Pre-injured lungs are prone to injury progression in response to mechanical ventilation. Heterogeneous ventilation due to (micro)atelectases imparts injurious strains on open alveoli (known as volutrauma). Hence, recruitment of (micro)atelec
Externí odkaz:
https://doaj.org/article/4cb35dbb795c4470a64393acdd535155
Autor:
Anton Selich, Jenni Fleischauer, Tina Roepke, Luisa Weisskoeppel, Melanie Galla, Constantin von Kaisenberg, Ulrich A. Maus, Axel Schambach, Michael Rothe
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Background Mesenchymal stromal cells (MSCs) are excessively investigated in the context of inflammation-driven diseases, but the clinical results are often moderate. MSCs are naturally activated by inflammatory signals, which lead to the sec
Externí odkaz:
https://doaj.org/article/7c94c09531e44c77b8ccdeeb9ca36465
Autor:
Agnes Kocher, Michael Simon, Andrew A. Dwyer, Catherine Blatter, Jasmina Bogdanovic, Patrizia Künzler-Heule, Peter M. Villiger, Diana Dan, Oliver Distler, Ulrich A. Walker, Dunja Nicca
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-17 (2023)
Abstract Background The Chronic Care Model (CCM) is a longstanding and widely adopted model guiding chronic illness management. Little is known about how CCM elements are implemented in rare disease care or how patients’ care experiences relate to
Externí odkaz:
https://doaj.org/article/edcf93b955f742c8b50f474626664643
Autor:
Tina Bormann, Regina Maus, Jennifer Stolper, Meritxell Tort Tarrés, Christina Brandenberger, Dirk Wedekind, Danny Jonigk, Tobias Welte, Jack Gauldie, Martin Kolb, Ulrich A. Maus
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a diffuse parenchymal lung disease characterized by exuberant deposition of extracellular matrix (ECM) proteins in the lung interstitium, which contributes to substantial morbidity and mortal
Externí odkaz:
https://doaj.org/article/21db241c974f480aaaa03111058bc8f0
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2650 (2023)
An innovative strategy to address recent challenges in the oral administration of poorly soluble drugs is the formulation of amorphous solid dispersions (ASDs), where the drug is dissolved in a highly soluble carrier polymer. Therefore, special knowl
Externí odkaz:
https://doaj.org/article/87342e9c987546b1920c9cf2e17f51ee
Publikováno v:
Bone Reports, Vol 17, Iss , Pp 101618- (2022)
Background: Age-related hyperkyphosis is multifactorial and involves alterations of vertebral bone, intervertebral discs (IVD) and paraspinal muscles. The relative contribution of these tissues remains unclear. Here, we compared differences in verteb
Externí odkaz:
https://doaj.org/article/af17563e02234518a4cc323a857123f6
Neural networks can learn spurious correlations in the data, often leading to performance disparity for underrepresented subgroups. Studies have demonstrated that the disparity is amplified when knowledge is distilled from a complex teacher model to
Externí odkaz:
http://arxiv.org/abs/2411.14984