Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Ulrich, Zügel"'
Autor:
Mark Peric, Sarah Koglin, Yvonne Dombrowski, Katrin Gross, Eva Bradac, Amanda Büchau, Andreas Steinmeyer, Ulrich Zügel, Thomas Ruzicka, Jürgen Schauber
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6340 (2009)
Antimicrobial peptides (AMPs) are strongly expressed in lesional skin in psoriasis and play an important role as proinflammatory "alarmins" in this chronic skin disease. Vitamin D analogs like calcipotriol have antipsoriatic effects and might mediate
Externí odkaz:
https://doaj.org/article/1ea4cc932ea94692a55cfdd9a88f4786
Convergence of IL-1beta and VDR activation pathways in human TLR2/1-induced antimicrobial responses.
Autor:
Philip T Liu, Mirjam Schenk, Valencia P Walker, Paul W Dempsey, Melissa Kanchanapoomi, Matthew Wheelwright, Aria Vazirnia, Xiaoran Zhang, Andreas Steinmeyer, Ulrich Zügel, Bruce W Hollis, Genhong Cheng, Robert L Modlin
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5810 (2009)
Antimicrobial effector mechanisms are central to the function of the innate immune response in host defense against microbial pathogens. In humans, activation of Toll-like receptor 2/1 (TLR2/1) on monocytes induces a vitamin D dependent antimicrobial
Externí odkaz:
https://doaj.org/article/d2709e7c21bd4bed8b82ec2be53446fd
Autor:
Arne von Bonin, Alexandra Rausch, Marion Hitchcock, Anne Mengel, Gabriele Leder, Wolf-Dietrich Döcke, Oliver von Ahsen, Stefan F. Martin, Lars Röse, Ulrich Zügel, Martin Krüger, Khusru Asadullah, Christine Stock, Claudia Merz
Publikováno v:
Experimental Dermatology. 20:41-47
T-cell-mediated processes play an essential role in the pathogenesis of several inflammatory skin diseases such as atopic dermatitis, allergic contact dermatitis and psoriasis. The aim of this study was to investigate the role of the IL-2-inducible t
Autor:
Martina U. Muckenthaler, Sibylle Dames, Christian Frauendorf, Jim Vadolas, Sandro Altamura, Manuela Aleku, Ulrich Zügel, Steffen Schubert, George Grigoriadis
Publikováno v:
Blood. 132:2340-2340
Accumulation of excess iron in tissues causes organ damage and dysfunction and may lead to serious clinical consequences including liver cirrhosis, diabetes, growth retardation and heart failure. Iron overload is a major health threat in iron loading
Autor:
Guido Heine, Ulrich Zügel, Andreas Radbruch, Magda Babina, Andreas Steinmeyer, Björn Hartmann, Margitta Worm
Publikováno v:
Allergy. 66:540-548
To cite this article: Hartmann B, Heine G, Babina M, Steinmeyer A, Zugel U, Radbruch A, Worm M. Targeting the vitamin D receptor inhibits the B cell-dependent allergic immune response. Allergy 2011; 66: 540–548. Abstract Background: 1α,25-dihydrox
Autor:
Arne von Bonin, Kai Licha, Alexandra Rausch, Rudolf Tauber, Rainer Haag, Sven Enders, Jens Dernedde, Marie Weinhart, Michael Schirner, Ulrich Zügel
Publikováno v:
Proceedings of the National Academy of Sciences. 107:19679-19684
Adhesive interactions of leukocytes and endothelial cells initiate leukocyte migration to inflamed tissue and are important for immune surveillance. Acute and chronic inflammatory diseases show a dysregulated immune response and result in a massive e
Autor:
Cherry Wongtrakool, Ulrich Zügel, Teresa Welch, Jesse Roman, Allan Ramirez, Andreas Steinmeyer
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 118:142-150
The mechanisms that control fibroproliferation and matrix deposition in lung fibrosis remain unclear. We speculate that vitamin D deficiency may contribute to pulmonary fibrosis since vitamin D deficiency has been implicated in several diseases. Firs
Publikováno v:
Experimental Dermatology. 18:619-627
The biologically active metabolite of vitamin D3, 1alpha,25-dihydroxyvitamin D3, has potent immunomodulatory activity; however, its clinical use is limited because of its hypercalcaemic activity in anti-inflammatory active doses. Here, we present ZK2
Publikováno v:
Nuclear Receptors as Drug Targets
Autor:
Qian-Chun Yun, Andreas Steinmeyer, Daniel D. Bikle, Yuko Oda, Ulrich Zügel, Jürgen Schauber, Richard L. Gallo, Amanda S. Büchau
Publikováno v:
Journal of Investigative Dermatology. 128(4):816-824
Hormonally active vitamin D(3)-1,25-dihydroxyvitamin D(3) (1,25D3)-acts as a signaling molecule in cutaneous immunity by increasing pattern recognition through Toll-like receptor-2 (TLR2), and increasing the expression and function of antimicrobial p