Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Ulrich, Theopold"'
Autor:
Dilan Khalili, Mubasher Mohammed, Martin Kunc, Martina Sindlerova, Johan Ankarklev, Ulrich Theopold
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTumor-associated macrophages may act to either limit or promote tumor growth, yet the molecular basis for either path is poorly characterized.MethodsWe use a larval Drosophila model that expresses a dominant-active version of the Ras-onco
Externí odkaz:
https://doaj.org/article/5eb3d955d25a44559ffd68543ba28b27
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionChitinase-like proteins (CLPs) are associated with tissue-remodeling and inflammation but also with several disorders, including fibrosis, atherosclerosis, allergies, and cancer. However, CLP’s role in tumors is far from clear. MethodsH
Externí odkaz:
https://doaj.org/article/52fc893ffaa1407981178991d5c60bff
Publikováno v:
Journal of Innate Immunity, Pp 1-15 (2021)
Fibrotic lesions accompany several pathological conditions, including tumors. We show that expression of a dominant-active form of the Ras oncogene in Drosophila salivary glands (SGs) leads to redistribution of components of the basement membrane (BM
Externí odkaz:
https://doaj.org/article/385755a0fac940dc9662b2af885f1165
Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
Understanding the tradeoffs that result from successful infection responses is central to understanding how life histories evolve. Gaining such insights, however, can be challenging, as they may be pathogen specific and confounded with experimental d
Externí odkaz:
https://doaj.org/article/3bf4f570dc0e4ed5b51c1d6fc17e0f03
Publikováno v:
eLife, Vol 9 (2020)
Postmitotic tissues are incapable of replacing damaged cells through proliferation, but need to rely on buffering mechanisms to prevent tissue disintegration. By constitutively activating the Ras/MAPK-pathway via RasV12-overexpression in the postmito
Externí odkaz:
https://doaj.org/article/9a2a7442136b4d7b82958437a96541b2
Publikováno v:
Fly, Vol 11, Iss 3, Pp 208-217 (2017)
One of the key factors that determine the interaction between hosts and their parasites is the frequency of their interactions, which depends on the locomotory behavior of both parts. To address host behavior we used natural infections involving inse
Externí odkaz:
https://doaj.org/article/6eb915b874b54326ba104247a49f10b5
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 7, Pp 2139-2149 (2017)
Many leukemia patients suffer from dysregulation of their immune system, making them more susceptible to infections and leading to general weakening (cachexia). Both adaptive and innate immunity are affected. The fruit fly Drosophila melanogaster has
Externí odkaz:
https://doaj.org/article/be810cc02b4c4a5fb9c90944be0bf743
Autor:
Alexis Dziedziech, Martin Schmid, Badrul Arefin, Thomas Kienzle, Robert Krautz, Ulrich Theopold
Publikováno v:
Data in Brief, Vol 25, Iss , Pp - (2019)
Insect hemolymph coagulation: Kinetics of classically and non-classically secreted clotting factors Schmid et al., 2019. The linked article demonstrates the localization of two secretory proteins in Drosophila melanogaster, Prophenoloxidase (PPO2) an
Externí odkaz:
https://doaj.org/article/3d6c7c5b76764d2aaf49f8b5b8808a07
Publikováno v:
Insects, Vol 11, Iss 9, p 577 (2020)
This special issue contains articles that add to the ever-expanding toolbox of insect pathogenic nematodes (entomopathogenic nematodes; EPNs) as well articles that provide new insights into the mutualistic interaction between EPNs and their hosts. Th
Externí odkaz:
https://doaj.org/article/b49eb62a5a574257b24b1b158c56ee38
Publikováno v:
Insects, Vol 11, Iss 1, p 60 (2020)
Entomopathogenic nematodes (EPNs) have been a useful model for studying wound healing in insects due to their natural mechanism of entering an insect host either through the cuticle or an orifice. While many experiments have shed light on nematode an
Externí odkaz:
https://doaj.org/article/7ce7b56b0d8e4820b5d5dc7bb366f7b3