Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Ulrich, Schweizer"'
Autor:
Holly Towell, Doreen Braun, Alexander Brol, Andrea di Fonzo, Eddy Rijntjes, Josef Köhrle, Ulrich Schweizer, Clemens Steegborn
Publikováno v:
Biomolecules, Vol 14, Iss 11, p 1373 (2024)
Iodothyronine deiodinases (Dio) are selenocysteine-containing membrane enzymes that activate and inactivate the thyroid hormones (TH) through reductive iodide eliminations. The three deiodinase isoforms are homodimers sharing highly conserved amino a
Externí odkaz:
https://doaj.org/article/907f963ea57340ad810a8e44403b42ad
Autor:
Kai Koch, Benedikt Duckworth-Mothes, Ulrich Schweizer, Karl-Ernst Grund, Tom G. Moreels, Alfred Königsrainer, Dörte Wichmann
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Endoscopy training models (ETM) using artificial organs are practical, hygienic and comfortable for trainees. However, few models exist for training endoscopic retrograde cholangiopancreatography (ERCP) in patients with surgically altered an
Externí odkaz:
https://doaj.org/article/7590be5b35ae4733a463b00b92239155
Autor:
Hamed Alborzinia, Zhiyi Chen, Umut Yildiz, Florencio Porto Freitas, Felix C E Vogel, Julianna Patricia Varga, Jasmin Batani, Christoph Bartenhagen, Werner Schmitz, Gabriele Büchel, Bernhard Michalke, Jashuo Zheng, Svenja Meierjohann, Enrico Girardi, Elisa Espinet, Andrés F Flórez, Ancely Ferreira dos Santos, Nesrine Aroua, Tasneem Cheytan, Julie Haenlin, Lisa Schlicker, Thamara N Xavier da Silva, Adriana Przybylla, Petra Zeisberger, Giulio Superti‐Furga, Martin Eilers, Marcus Conrad, Marietta Fabiano, Ulrich Schweizer, Matthias Fischer, Almut Schulze, Andreas Trumpp, José Pedro Friedmann Angeli
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 8, Pp 1-17 (2023)
Abstract Ferroptosis has emerged as an attractive strategy in cancer therapy. Understanding the operational networks regulating ferroptosis may unravel vulnerabilities that could be harnessed for therapeutic benefit. Using CRISPR‐activation screens
Externí odkaz:
https://doaj.org/article/f738f088a5b24d4d84df76ffa09916f9
Autor:
Carolin Lisa Michaela Ludwig, Simon Bohleber, Rebecca Lapp, Alexander Rebl, Eva Katrin Wirth, Martina Langhammer, Ulrich Schweizer, Joachim M. Weitzel, Marten Michaelis
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-16 (2023)
Abstract The development and maturation of ovarian follicles is a complex and highly regulated process, which is essential for successful ovulation. During recent decades, several mouse models provided insights into the regulation of folliculogenesis
Externí odkaz:
https://doaj.org/article/0c473caab59c408e9f2bc99bc4e46ba8
Autor:
Dörte Wichmann, Dietmar Stüker, Ulrich Schweizer, Moritz Senne, Benedikt Duckworth-Mothes, Emanuel Zerabruck, Alfred Königsrainer, Jeannine Bachmann
Publikováno v:
Frontiers in Surgery, Vol 10 (2023)
Background and study aimEndoscopic negative pressure therapy (ENPT) is well established in the treatment of perforations of various etiologies in the upper and lower gastrointestinal tract. For duodenal perforations exist only case reports and series
Externí odkaz:
https://doaj.org/article/5cc538a18a2a48bfad579e8b7c091316
Autor:
Ulrich Schweizer, Eva K. Wirth, Thomas Klopstock, Sabine M. Hölter, Lore Becker, Jackob Moskovitz, Tilman Grune, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabe de Angelis, Josef Köhrle, Lutz Schomburg
Publikováno v:
Redox Biology, Vol 57, Iss , Pp 102490- (2022)
Mice with constitutive disruption of the Selenop gene have been key to delineate the importance of selenoproteins in neurobiology. However, the phenotype of this mouse model is exquisitely dependent on selenium supply and timing of selenium supplemen
Externí odkaz:
https://doaj.org/article/339455800f054b43a1117382fc1a7aa8
Autor:
Julian Schneider, Benedikt Duckworth-Mothes, Ulrich Schweizer, Alfred Königsrainer, Jakob Fisch, Dörte Wichmann
Publikováno v:
Bioengineering, Vol 10, Iss 5, p 523 (2023)
Background: Endoscopic retrograde cholangiopancreatography (ERCP) is crucial to the treatment of biliopancreatic diseases with iatrogenic perforation as a potential complication. As of yet, the wall load during ERCP is unknown, as it is not directly
Externí odkaz:
https://doaj.org/article/532fa13006dd4cc2afaca300bed18f31
Autor:
Noelia Fradejas-Villar, Wenchao Zhao, Uschi Reuter, Michael Doengi, Irina Ingold, Simon Bohleber, Marcus Conrad, Ulrich Schweizer
Publikováno v:
Redox Biology, Vol 48, Iss , Pp 102188- (2021)
Selenoproteins are a small family of proteins containing the trace element selenium in form of the rare amino acid selenocysteine (Sec), which is decoded by the UGA codon. In humans, a number of pathogenic variants in genes encoding distinct selenopr
Externí odkaz:
https://doaj.org/article/f6302178548c423e8a2aad1b6790908b
Publikováno v:
Biomolecules, Vol 12, Iss 10, p 1504 (2022)
Co-translational incorporation of selenocysteine (Sec) into selenoproteins occurs at UGA codons in a process in which translational elongation competes with translational termination. Selenocysteine insertion sequence-binding protein 2 (SECISBP2) gre
Externí odkaz:
https://doaj.org/article/4504362c517646c2b171a7b89b608e6c
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Eighteen years ago, unexpected epileptic seizures in Selenop-knockout mice pointed to a potentially novel, possibly underestimated, and previously difficult to study role of selenium (Se) in the mammalian brain. This mouse model was the key to open t
Externí odkaz:
https://doaj.org/article/aa812168596d4f91b318c6c333a56aa7