Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Ulrich, Pfeffer"'
Autor:
Sonia Minuzzo, Valentina Agnusdei, Marica Pinazza, Adriana A. Amaro, Valeria Sacchetto, Ulrich Pfeffer, Roberta Bertorelle, Orietta Spinelli, Valentina Serafin, Stefano Indraccolo
Publikováno v:
Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-5 (2023)
Abstract T-cell acute lymphoblastic leukemia (T-ALL) is a hematologic tumor, characterized by several genetic alterations, that constitutes 15% of pediatric and 25% of adult ALL. While with current therapeutic protocols children and adults’ overall
Externí odkaz:
https://doaj.org/article/36be6ad892594513b16b96a6cc551955
Autor:
Adriana Amaro, Francesco Reggiani, Daniela Fenoglio, Rosaria Gangemi, Anna Tosi, Alessia Parodi, Barbara Banelli, Valentina Rigo, Luca Mastracci, Federica Grillo, Alessandra Cereghetti, Aizhan Tastanova, Adhideb Ghosh, Fabio Sallustio, Laura Emionite, Antonio Daga, Tiziana Altosole, Gilberto Filaci, Antonio Rosato, Mitchell Levesque, Michele Maio, Ulrich Pfeffer, Michela Croce, EPigenetic Immune-oncology Consortium Airc (EPICA) consortium
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-24 (2023)
Abstract Background The combination of Programmed Cell Death 1 (PD-1) and Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) blockade has dramatically improved the overall survival rate for malignant melanoma. Immune checkpoint blockers (ICBs) limit the tumor
Externí odkaz:
https://doaj.org/article/54d112fcea9d430e9f590e99dd740788
Autor:
Irene Vanni, Milena Casula, Lorenza Pastorino, Antonella Manca, Bruna Dalmasso, Virginia Andreotti, Marina Pisano, Maria Colombino, Italian Association for Cancer Research (AIRC) Study Group, Ulrich Pfeffer, Enrica Teresa Tanda, Carla Rozzo, Panagiotis Paliogiannis, Antonio Cossu, Paola Ghiorzo, Giuseppe Palmieri, for the Italian Melanoma Intergroup (IMI)
Publikováno v:
Diagnostic Pathology, Vol 15, Iss 1, Pp 1-18 (2020)
Abstract Background Identification of somatic mutations in key oncogenes in melanoma is important to lead the effective and efficient use of personalized anticancer treatment. Conventional methods focus on few genes per run and, therefore, are unable
Externí odkaz:
https://doaj.org/article/69d423c7d1ab4b458a345ad25ac7c05f
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3240 (2022)
There is a growing number of multi-domain genomic datasets for human tumors. Multi-domain data are usually interpreted after separately analyzing single-domain data and integrating the results post hoc. Data fusion techniques allow for the real integ
Externí odkaz:
https://doaj.org/article/4b8863af320c46cd83b420cd81d5e22c
Autor:
Simona Caporali, Adriana Amaro, Lauretta Levati, Ester Alvino, Pedro Miguel Lacal, Simona Mastroeni, Federica Ruffini, Laura Bonmassar, Gian Carlo Antonini Cappellini, Nadia Felli, Alessandra Carè, Ulrich Pfeffer, Stefania D’Atri
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-24 (2019)
Abstract Background Development of resistance to inhibitors of BRAF (BRAFi) and MEK (MEKi) remains a great challenge for targeted therapy in patients with BRAF-mutant melanoma. Here, we explored the role of miRNAs in melanoma acquired resistance to B
Externí odkaz:
https://doaj.org/article/ad44b34751c2441eb4d91f50e0307725
Autor:
Paolo Romano, Arnaud Céol, Andreas Dräger, Antonino Fiannaca, Rosalba Giugno, Massimo La Rosa, Luciano Milanesi, Ulrich Pfeffer, Riccardo Rizzo, Soo-Yong Shin, Junfeng Xia, Alfonso Urso
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S4, Pp 1-9 (2019)
Abstract The 17th International NETTAB workshop was held in Palermo, Italy, on October 16-18, 2017. The special topic for the meeting was “Methods, tools and platforms for Personalised Medicine in the Big Data Era”, but the traditional topics of
Externí odkaz:
https://doaj.org/article/228d6df20cb84bef9cb99ec2b9f55a52
Autor:
Valentina Agnusdei, Sonia Minuzzo, Marica Pinazza, Alessandra Gasparini, Laura Pezzè, Adriana Agnese Amaro, Lorenza Pasqualini, Paola Del Bianco, Martina Tognon, Chiara Frasson, Pietro Palumbo, Yari Ciribilli, Ulrich Pfeffer, Massimo Carella, Alberto Amadori, Stefano Indraccolo
Publikováno v:
Haematologica, Vol 105, Iss 5 (2020)
Despite substantial progress in treatment of T-cell acute lymphoblastic leukemia (T-ALL), mortality remains relatively high, mainly due to primary or acquired resistance to chemotherapy. Further improvements in survival demand better understanding of
Externí odkaz:
https://doaj.org/article/9da59cf5276c4fad8340659c500323c4
Autor:
Claudia Lo Sicco, Daniele Reverberi, Federico Villa, Ulrich Pfeffer, Rodolfo Quarto, Ranieri Cancedda, Roberta Tasso
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-13 (2018)
Abstract Background Restoration of damaged tissues through the activation of endogenous progenitors is an attractive therapeutic option. A deep evaluation of the intrinsic stem/progenitor cell properties as well as the reciprocal interactions with in
Externí odkaz:
https://doaj.org/article/d6a38cc8f9834db785e642b1e9808a49
Autor:
Arinna Bertoni, Federica Penco, Hilaria Mollica, Paola Bocca, Ignazia Prigione, Anna Corcione, Davide Cangelosi, Francesca Schena, Genny Del Zotto, Adriana Amaro, Noemi Paladino, Emanuele Pontali, Marcello Feasi, Sara Signa, Marta Bustaffa, Roberta Caorsi, Serena Palmeri, Paola Contini, Raffaele De Palma, Ulrich Pfeffer, Paolo Uva, Anna Rubartelli, Marco Gattorno, Stefano Volpi
Publikováno v:
Journal of Allergy and Clinical Immunology. 150:796-805
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may result in a severe pneumonia associated with elevation of blood inflammatory parameters, reminiscent of cytokine storm syndrome. Steroidal anti-inflammatory therapies have sho
Autor:
Francesco Reggiani, Marianna Ambrosio, Alessandra Forlani, Anna Morabito, Adriana Amaro, Ulrich Pfeffer
Publikováno v:
Diagnostics and Therapeutics. :2-5