Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Ulrich, Hommel"'
Autor:
Ulrich Hommel, Konstanze Hurth, Jean-Michel Rondeau, Anna Vulpetti, Daniela Ostermeier, Andreas Boettcher, Jacob Peter Brady, Michael Hediger, Sylvie Lehmann, Elke Koch, Anke Blechschmidt, Rina Yamamoto, Valentina Tundo Dottorello, Sandra Haenni-Holzinger, Christian Kaiser, Philipp Lehr, Andreas Lingel, Luca Mureddu, Christian Schleberger, Jutta Blank, Paul Ramage, Felix Freuler, Joerg Eder, Frédéric Bornancin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Human interleukin-1β (hIL-1β) is a pro-inflammatory cytokine involved in many diseases. While hIL-1β directed antibodies have shown clinical benefit, an orally available low-molecular weight antagonist is still elusive, limiting the appli
Externí odkaz:
https://doaj.org/article/045a20bdd9464a2d8a11a51d75b0961e
Autor:
Jian Ding, Guo Li, Hejun Liu, Lulu Liu, Ying Lin, Jingyan Gao, Guoqiang Zhou, Lingling Shen, Mengxi Zhao, Yanyan Yu, Weihui Guo, Ulrich Hommel, Johannes Ottl, Jutta Blank, Nicola Aubin, Yi Wei, Hu He, David R. Sage, Peter W. Atadja, En Li, Rishi K. Jain, John A. Tallarico, Stephen M. Canham, Ying-Ling Chiang, He Wang
Publikováno v:
ACS Chemical Biology. 18:34-40
WD repeat domain 5 (WDR5) is a member of the WD40-repeat protein family that plays a critical role in multiple processes. It is also a prominent target for pharmacological inhibition in diseases such as cancer, aging, and neurodegenerative disorders.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6be8f58a3f8f57cbd62279d195187665
https://doi.org/10.1021/acschembio.2c00843
https://doi.org/10.1021/acschembio.2c00843
Publikováno v:
Journal of Management Development, 2016, Vol. 35, Issue 5, pp. 606-622.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/JMD-08-2014-0088
Autor:
Anna Vulpetti, Andrew Proudfoot, Andreas Lingel, Christelle Henry, Andreas O. Frank, Regis Denay, Tony Reinsperger, Alexandra Frommlet, Ulrich Hommel, Burkhard Luy, Alvar D. Gossert
Publikováno v:
Angewandte Chemie International Edition. 59:14809-14817
Fragment-based lead discovery has become a fundamental approach to identify ligands that efficiently interact with disease-relevant targets. Among the numerous screening techniques, fluorine-detected NMR has gained popularity owing to its high sensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c3d9f862e00337c6d5f95a852d5026
https://doi.org/10.1002/anie.202002463
https://doi.org/10.1002/anie.202002463
Publikováno v:
Falkenstein, M, Hommel, U & Snelson-Powell, A 2022, ' COVID 19: accelerator or demolisher of the RME Agenda? ', Journal of Global Responsibility, vol. 13, no. 1, pp. 87-100 . https://doi.org/10.1108/JGR-12-2020-0109
PurposeThe purpose of this paper is to enrich the discussion at the intersection of responsible management education (RME) and the pandemic with new views that explore together the inhibitors of and drivers for a strengthening of RME in the emerging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60b3851ae6a310cd6f8373101ff84687
https://purehost.bath.ac.uk/ws/files/225870827/falkensteinEtal_JGR_2021.pdf
https://purehost.bath.ac.uk/ws/files/225870827/falkensteinEtal_JGR_2021.pdf
Publikováno v:
Accounting & Finance. 59:1923-1946
This paper studies systemic risk in the Chinese debt market stemming from inter‐corporate loan guarantees using field data from Zhejiang Province. We apply a weighted and directed network model to analyse the implications for default contagion and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4074dbcae9f42ee13e97f55baf8b382
https://doi.org/10.1111/acfi.12549
https://doi.org/10.1111/acfi.12549
Publikováno v:
Finance Research Letters. 27:105-112
This study investigates the network topology of equity volatilities. We propose a novel approach to model the interdependencies of the Euro Stoxx companies by constructing the minimum spanning tree with the upper tail dependence coefficient of the eq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15c0b1edbd141ff78676f6dd1e687f86
https://doi.org/10.1016/j.frl.2018.02.016
https://doi.org/10.1016/j.frl.2018.02.016
Autor:
Alvar Gossert, Anna Vulpetti, Ulrich Hommel, Tony Reinsperger, Alexandra Frommlet, Regis Denay, Andreas Lingel, Andrew Proudfoot, Burkhard Luy, Christelle Henry, Andreas Frank
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d02bc1ed11ec3dbd305694bf60666ed0
https://doi.org/10.1021/scimeetings.0c07139
https://doi.org/10.1021/scimeetings.0c07139
Autor:
Andreas, Lingel, Anna, Vulpetti, Tony, Reinsperger, Andrew, Proudfoot, Regis, Denay, Alexandra, Frommlet, Christelle, Henry, Ulrich, Hommel, Alvar D, Gossert, Burkhard, Luy, Andreas O, Frank
Publikováno v:
Angewandte Chemie (International ed. in English). 59(35)
Fragment-based lead discovery has become a fundamental approach to identify ligands that efficiently interact with disease-relevant targets. Among the numerous screening techniques, fluorine-detected NMR has gained popularity owing to its high sensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4862930872d9705620c4b086ef948d22
https://pubmed.ncbi.nlm.nih.gov/32363632
https://pubmed.ncbi.nlm.nih.gov/32363632