Zobrazeno 1 - 10
of 381
pro vyhledávání: '"Ulrich, Herrlinger"'
Autor:
Frank A. Giordano, Julian P. Layer, Sonia Leonardelli, Lea L. Friker, Roberta Turiello, Dillon Corvino, Thomas Zeyen, Christina Schaub, Wolf Müller, Elena Sperk, Leonard Christopher Schmeel, Katharina Sahm, Christoph Oster, Sied Kebir, Peter Hambsch, Torsten Pietsch, Sotirios Bisdas, Michael Platten, Martin Glas, Clemens Seidel, Ulrich Herrlinger, Michael Hölzel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The chemokine CXCL12 promotes glioblastoma (GBM) recurrence after radiotherapy (RT) by facilitating vasculogenesis. Here we report outcomes of the dose-escalation part of GLORIA (NCT04121455), a phase I/II trial combining RT and the CXCL12-n
Externí odkaz:
https://doaj.org/article/a461b70c215e421cabb2b9a14f5dfb4b
Autor:
Matthias Schneider, Christian Wispel, Anna-Laura Potthoff, Muriel Heimann, Valeri Borger, Christina Schaub, Ulrich Herrlinger, Hartmut Vatter, Patrick Schuss, Niklas Schäfer
Publikováno v:
Current Oncology, Vol 31, Iss 5, Pp 2410-2419 (2024)
Therapeutic management of patients with leptomeningeal carcinomatosis (LC) may require treatment of concomitant hydrocephalus (HC) in addition to intrathecal chemotherapy (ITC). Ventriculoperitoneal shunts (VPS) equipped with a valve for manual deact
Externí odkaz:
https://doaj.org/article/ae2002eb9d0a4d148773a7022c96e2a6
Autor:
Sophie Heuer, Ina Burghaus, Maria Gose, Tobias Kessler, Felix Sahm, Philipp Vollmuth, Varun Venkataramani, Dirk Hoffmann, Matthias Schlesner, Miriam Ratliff, Carsten Hopf, Ulrich Herrlinger, Franz Ricklefs, Martin Bendszus, Sandro M. Krieg, Antje Wick, Wolfgang Wick, Frank Winkler
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Glioblastoma is the most frequent and a particularly malignant primary brain tumor with no efficacy-proven standard therapy for recurrence. It has recently been discovered that excitatory synapses of the AMPA-receptor subtype form
Externí odkaz:
https://doaj.org/article/791cfad4114e476ba6f0d9883da9662b
Autor:
Niklas Grassl, Katharina Sahm, Heike Süße, Isabel Poschke, Lukas Bunse, Theresa Bunse, Tamara Boschert, Iris Mildenberger, Anne-Kathleen Rupp, Max Philipp Ewinger, Lisa-Marie Lanz, Monika Denk, Ghazaleh Tabatabai, Michael W. Ronellenfitsch, Ulrich Herrlinger, Martin Glas, Dietmar Krex, Peter Vajkoczy, Antje Wick, Inga Harting, Felix Sahm, Andreas von Deimling, Martin Bendszus, Wolfgang Wick, Michael Platten
Publikováno v:
Neurological Research and Practice, Vol 5, Iss 1, Pp 1-6 (2023)
Abstract Introduction Diffuse midline gliomas (DMG) are universally lethal central nervous system tumors that carry almost unanimously the clonal driver mutation histone-3 K27M (H3K27M). The single amino acid substitution of lysine to methionine harb
Externí odkaz:
https://doaj.org/article/968882c501c548889b7af8e6c08a2e21
Autor:
Agostina Stradella, Francois Ghiringhelli, Ana Maia, Macarena Gonzalez, Cécile Gouttefangeas, Ulrich Herrlinger, David Reardon, Ahmed Idbaih, Patrick Wen, Ghazaleh Tabatabai, Wolfgang Wick, Mirjam Renovanz, Maria Vieito Villar, Christophe Bonny, Joao Gamelas Magalhaes, Hélène Toussaint, Jean-Michel Paillarse, Marta GilMartin, Iris Mildenberger, Michael C Burger, Alice Hervieu, Mehdi Touat, Antje Wick
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/b66bf531835946ef99e16b169d7cc47a
Autor:
Marco M. E. Vogel, Arthur Wagner, Jens Gempt, Harald Krenzlin, Thomas Zeyen, Richard Drexler, Martin Voss, Charlotte Nettekoven, Tammam Abboud, Dorothee Mielke, Veit Rohde, Marco Timmer, Roland Goldbrunner, Joachim P. Steinbach, Lasse Dührsen, Manfred Westphal, Ulrich Herrlinger, Florian Ringel, Bernhard Meyer, Stephanie E. Combs
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract The severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) has changed the clinical day-to-day practice. The aim of this study was to evaluate the impact of the pandemic on patients with high-grade glioma (HGG) as well as to deriv
Externí odkaz:
https://doaj.org/article/e8cd6733dae945f5a79bd251874ac446
Autor:
Julian P. Layer, Katharina Layer, Gustavo R. Sarria, Fred Röhner, Cas S. Dejonckheere, Lea L. Friker, Thomas Zeyen, David Koch, Davide Scafa, Christina Leitzen, Mümtaz Köksal, Frederic Carsten Schmeel, Niklas Schäfer, Jennifer Landsberg, Michael Hölzel, Ulrich Herrlinger, Matthias Schneider, Frank A. Giordano, Leonard Christopher Schmeel
Publikováno v:
Current Oncology, Vol 30, Iss 2, Pp 1300-1313 (2023)
Purpose: To determine the safety and outcome profile of five-fraction stereotactic radiotherapy (FSRT) for brain metastases (BM), either as a definitive or adjuvant treatment. Methods: We assessed clinical data of patients receiving five fractions of
Externí odkaz:
https://doaj.org/article/14acb167281c4e949dff21e05e773afc
Autor:
Johannes Wach, Tim Lampmann, Ági Güresir, Hartmut Vatter, Ulrich Herrlinger, Albert Becker, Marieta Toma, Michael Hölzel, Erdem Güresir
Publikováno v:
Current Oncology, Vol 29, Iss 7, Pp 5026-5041 (2022)
Abducens nerve palsy is a severe dysfunction after petroclival meningioma (PC MNG) surgery. The objective of this investigation was to analyze abducens nerve outcomes in patients who underwent the retrosigmoid approach in relation to the MIB-1 index.
Externí odkaz:
https://doaj.org/article/8524985890b6483c824078d6fe0ba23a
Autor:
Thomas Zeyen, Anna-Laura Potthoff, Robert Nemeth, Dieter H. Heiland, Michael C. Burger, Joachim P. Steinbach, Peter Hau, Ghazaleh Tabatabai, Martin Glas, Uwe Schlegel, Oliver Grauer, Dietmar Krex, Oliver Schnell, Roland Goldbrunner, Michael Sabel, Niklas Thon, Daniel Delev, Hans Clusmann, Clemens Seidel, Erdem Güresir, Matthias Schmid, Patrick Schuss, Frank A. Giordano, Alexander Radbruch, Albert Becker, Johannes Weller, Christina Schaub, Hartmut Vatter, Judith Schilling, Frank Winkler, Ulrich Herrlinger, Matthias Schneider
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background Glioblastoma is the most frequent and malignant primary brain tumor. Even in the subgroup with O-6-methylguanine-DNA methyltransferase (MGMT) promoter methylation and favorable response to first-line therapy, survival after relaps
Externí odkaz:
https://doaj.org/article/a07626c82ec8444ab56a35322801927a
Autor:
Motaz Hamed, Simon Brandecker, Shaleen Rana, Anna-Laura Potthoff, Lars Eichhorn, Christian Bode, Frederic Carsten Schmeel, Alexander Radbruch, Niklas Schäfer, Ulrich Herrlinger, Mümtaz Köksal, Frank Anton Giordano, Hartmut Vatter, Matthias Schneider, Mohammed Banat
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectivePatients with spinal metastasis (SM) are at advanced stages of systemic cancer disease. Surgical therapy for SM is a common treatment modality enabling histopathological diagnosis and the prevention of severe neurological deficits. However,
Externí odkaz:
https://doaj.org/article/6b9e53cdc4fb45789cf2bc8bc019f6d9