Zobrazeno 1 - 10
of 516
pro vyhledávání: '"Ulrich, Dirnagl"'
Autor:
Juliet Roudini, Sarah Weschke, Torsten Rackoll, Ulrich Dirnagl, Gordon Guyatt, Hamidreza Khankeh
Publikováno v:
Systematic Reviews, Vol 12, Iss 1, Pp 1-6 (2023)
Abstract This protocol describes a systematic scoping review of Stroke Patient and Stakeholder Engagement (SPSE), concepts, definitions, models, implementation strategies, indicators, or frameworks. The active engagement of patients and other stakeho
Externí odkaz:
https://doaj.org/article/befe6ebe8417489cb745752d162bb1bb
Autor:
Natascha Ingrid Drude, Lorena Martinez-Gamboa, Meggie Danziger, Anja Collazo, Silke Kniffert, Janine Wiebach, Gustav Nilsonne, Frank Konietschke, Sophie K. Piper, Samuel Pawel, Charlotte Micheloud, Leonhard Held, Florian Frommlet, Daniel Segelcke, Esther M. Pogatzki-Zahn, Bernhard Voelkl, Tim Friede, Edgar Brunner, Astrid Dempfle, Bernhard Haller, Marie Juliane Jung, Lars Björn Riecken, Hans-Georg Kuhn, Matthias Tenbusch, Lina Maria Serna Higuita, Edmond J. Remarque, Servan Luciano Grüninger-Egli, Katrin Manske, Sebastian Kobold, Marion Rivalan, Lisa Wedekind, Juliane C. Wilcke, Anne-Laure Boulesteix, Marcus W. Meinhardt, Rainer Spanagel, Simone Hettmer, Irene von Lüttichau, Carla Regina, Ulrich Dirnagl, Ulf Toelch
Publikováno v:
Translational Medicine Communications, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract Clinical translation from bench to bedside often remains challenging even despite promising preclinical evidence. Among many drivers like biological complexity or poorly understood disease pathology, preclinical evidence often lacks desired
Externí odkaz:
https://doaj.org/article/bf47b97f5e2949fb928a3da8d60cd224
Autor:
Kelly D Cobey, Stefanie Haustein, Jamie Brehaut, Ulrich Dirnagl, Delwen L Franzen, Lars G Hemkens, Justin Presseau, Nico Riedel, Daniel Strech, Juan Pablo Alperin, Rodrigo Costas, Emily S Sena, Thed van Leeuwen, Clare L Ardern, Isabel O L Bacellar, Nancy Camack, Marcos Britto Correa, Roberto Buccione, Maximiliano Sergio Cenci, Dean A Fergusson, Cassandra Gould van Praag, Michael M Hoffman, Renata Moraes Bielemann, Ugo Moschini, Mauro Paschetta, Valentina Pasquale, Valeria E Rac, Dylan Roskams-Edris, Hermann M Schatzl, Jo Anne Stratton, David Moher
Publikováno v:
PLoS Biology, Vol 21, Iss 1, p e3001949 (2023)
The state of open science needs to be monitored to track changes over time and identify areas to create interventions to drive improvements. In order to monitor open science practices, they first need to be well defined and operationalized. To reach
Externí odkaz:
https://doaj.org/article/9e78ec29582e4f288e041b8be057ab2e
Autor:
Clemens Messerschmidt, Marco Foddis, Sonja Blumenau, Susanne Müller, Kajetan Bentele, Manuel Holtgrewe, Celia Kun-Rodrigues, Isabel Alonso, Maria do Carmo Macario, Ana Sofia Morgadinho, Ana Graça Velon, Gustavo Santo, Isabel Santana, Saana Mönkäre, Liina Kuuluvainen, Johanna Schleutker, Minna Pöyhönen, Liisa Myllykangas, Assunta Senatore, Daniel Berchtold, Katarzyna Winek, Andreas Meisel, Aleksandra Pavlovic, Vladimir Kostic, Valerija Dobricic, Ebba Lohmann, Hasmet Hanagasi, Gamze Guven, Basar Bilgic, Jose Bras, Rita Guerreiro, Dieter Beule, Ulrich Dirnagl, Celeste Sassi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Recently, several genome-wide association studies identified PHACTR1 as key locus for five diverse vascular disorders: coronary artery disease, migraine, fibromuscular dysplasia, cervical artery dissection and hypertension. Although these re
Externí odkaz:
https://doaj.org/article/fd269f7adb7a4eddb42c68dbb59da734
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 2, Pp n/a-n/a (2022)
A spectre is haunting biomedical research: It appears that a substantial fraction of published research results cannot be reproduced, while spectacularly successful novel treatments developed in experimental models of disease too often fail in clinic
Externí odkaz:
https://doaj.org/article/bfc8df76cf9b40d48a6c6004d938a4fa
Autor:
Nathalie Percie du Sert, Viki Hurst, Amrita Ahluwalia, Sabina Alam, Marc T. Avey, Monya Baker, William J. Browne, Alejandra Clark, Innes C. Cuthill, Ulrich Dirnagl, Michael Emerson, Paul Garner, Stephen T. Holgate, David W. Howells, Natasha A. Karp, Stanley E. Lazic, Katie Lidster, Catriona J. MacCallum, Malcolm Macleod, Esther J. Pearl, Ole H. Petersen, Frances Rawle, Penny Reynolds, Kieron Rooney, Emily S. Sena, Shai D. Silberberg, Thomas Steckler, Hanno Würbel
Publikováno v:
BMC Veterinary Research, Vol 16, Iss 1, Pp 1-7 (2020)
Abstract Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the reporting of animal research. They consist of a checklist of info
Externí odkaz:
https://doaj.org/article/ea37cc3bf4b84470b591684c9c09631e
Autor:
Melanie T. C. Kuffner, Stefan P. Koch, Marieluise Kirchner, Susanne Mueller, Janet Lips, Jeehye An, Philipp Mertins, Ulrich Dirnagl, Matthias Endres, Philipp Boehm-Sturm, Christoph Harms, Christian J. Hoffmann
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
AimsCarotid artery disease is frequent and can result in chronic modest hypoperfusion of the brain. If no transient ischemic attack or stroke occur, it is classified asymptomatic. In the long-term, though, it can lead to cognitive impairment. Fosteri
Externí odkaz:
https://doaj.org/article/2c0c2952aeb14ee5809eafc2724c1a93
Autor:
Anton Bespalov, René Bernard, Anja Gilis, Björn Gerlach, Javier Guillén, Vincent Castagné, Isabel A Lefevre, Fiona Ducrey, Lee Monk, Sandrine Bongiovanni, Bruce Altevogt, María Arroyo-Araujo, Lior Bikovski, Natasja de Bruin, Esmeralda Castaños-Vélez, Alexander Dityatev, Christoph H Emmerich, Raafat Fares, Chantelle Ferland-Beckham, Christelle Froger-Colléaux, Valerie Gailus-Durner, Sabine M Hölter, Martine CJ Hofmann, Patricia Kabitzke, Martien JH Kas, Claudia Kurreck, Paul Moser, Malgorzata Pietraszek, Piotr Popik, Heidrun Potschka, Ernesto Prado Montes de Oca, Leonardo Restivo, Gernot Riedel, Merel Ritskes-Hoitinga, Janko Samardzic, Michael Schunn, Claudia Stöger, Vootele Voikar, Jan Vollert, Kimberley E Wever, Kathleen Wuyts, Malcolm R MacLeod, Ulrich Dirnagl, Thomas Steckler
Publikováno v:
eLife, Vol 10 (2021)
While high risk of failure is an inherent part of developing innovative therapies, it can be reduced by adherence to evidence-based rigorous research practices. Supported through the European Union’s Innovative Medicines Initiative, the EQIPD conso
Externí odkaz:
https://doaj.org/article/056d0e1179a847c792213de97e872285
Autor:
Rima-Maria Rahal, Susann Fiedler, Adeyemi Adetula, Ronnie P.-A. Berntsson, Ulrich Dirnagl, Gordon B. Feld, Christian J. Fiebach, Samsad Afrin Himi, Aidan J. Horner, Tina B. Lonsdorf, Felix Schönbrodt, Miguel Alejandro A. Silan, Michael Wenzler, Flávio Azevedo
Publikováno v:
Nature Human Behaviour. 7:164-167
High-quality research requires appropriate employment and working conditions for researchers. However, many academic systems rely on short-term employment contracts, biased selection procedures and misaligned incentives, which hinder research quality
Publikováno v:
PLoS Biology, Vol 19, Iss 4, p e3001140 (2021)
In this response to Labib and Evans, authors of the Hong Kong Principles look forward to collaborating with those from the broad research integrity community to ensure that issues of equity, diversity and inclusion will become part of the ecosystem o
Externí odkaz:
https://doaj.org/article/7f8e47636251492d9cfccd787b41e0d6