Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ulrica Tostar"'
Autor:
Ulrica Tostar, Csaba Finta, Mohammed Ferdous-Ur Rahman, Takashi Shimokawa, Peter G Zaphiropoulos
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37761 (2012)
The Suppressor of Fused (SUFU) protein plays an essential role in the Hedgehog (HH) signaling pathway, by regulation of the GLI transcription factors. Two major isoforms of human SUFU are known, a full-length (SUFU-FL) and a carboxy-terminal truncate
Externí odkaz:
https://doaj.org/article/ee450d94fb0d42eb9854702ee3d739c3
Autor:
Peter G. Zaphiropoulos, Mona Ståhle, Enikö Sonkoly, Ulrica Tostar, Takashi Shimokawa, Ramesh Palaniswamy, Andor Pivarcsi, Mohammed Ferdous-Ur Rahman
Publikováno v:
RNA Biology
The Hedgehog (HH) signaling pathway has important roles in tumorigenesis and in embryonal patterning. The Glioma-associated oncogene 1 (GLI1) is a key molecule in HH signaling, acting as a transcriptional effector and, moreover, is considered to be a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ce624dff8fd5269f96e824c6d2b4a9
https://repo.qst.go.jp/records/46769
https://repo.qst.go.jp/records/46769
Autor:
Rune Toftgård, Matthias Lauth, Ulrica Tostar, Ramesh Palaniswamy, Maria Kasper, Takashi Shimokawa, Peter G. Zaphiropoulos
Publikováno v:
The Journal of Biological Chemistry
Hedgehog (HH) signaling is one of the key pathways with major significance for embryogenesis, tumorigenesis, and stem cell maintenance. Glioma-associated oncogene 1 (GLI1) is a transcription factor that acts as the terminal signaling effector but als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11bac845efa861081585fb3af635dbb0
http://europepmc.org/articles/PMC2386930
http://europepmc.org/articles/PMC2386930
Publikováno v:
Genescancer. 1(9)
Rhabdomyosarcoma (RMS) is the most frequent soft-tissue sarcoma in children. Embryonal rhabdomyosarcoma (E-RMS) represents the most common RMS subtype, but the molecular events driving this tumor are still largely unknown. The hedgehog (HH) pathway,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80744d60f5115fef3e241a231c601ef6
https://pubmed.ncbi.nlm.nih.gov/21779473
https://pubmed.ncbi.nlm.nih.gov/21779473
Autor:
Matthias Lauth, Volker Fendrich, Carmen Guerra, Ulrica Tostar, Takashi Shimokawa, Mariano Barbacid, Rune Toftgård, Åsa Bergström, Qianren Jin
Publikováno v:
Nature structuralmolecular biology. 17(6)
Synergism between the RAS and Hedgehog (HH) pathways has been suggested for carcinogenesis in the pancreas, lung and colon. We investigated the molecular cross-talk between RAS and HH signaling and found that, although mutant RAS induces or enhances
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb956f5eb0a46e7e274dba94f41e941
https://pubmed.ncbi.nlm.nih.gov/20512148
https://pubmed.ncbi.nlm.nih.gov/20512148
Autor:
Rune Toftgård, Carl Johan Malm, Anne Birgitte Undén, Lars-Gunnar Kindblom, Jeanne M. Meis-Kindblom, Ulrica Tostar
Publikováno v:
The Journal of pathology. 208(1)
The naevoid basal cell carcinoma syndrome (NBCCS) is caused by mutations in the hedgehog receptor PTCH gene. It is characterized by developmental defects and a predisposition to the development of certain tumours, such as basal cell carcinoma, medull
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147ca2a3520a172dd596dcce38de4fdd
https://pubmed.ncbi.nlm.nih.gov/16294371
https://pubmed.ncbi.nlm.nih.gov/16294371