RNA interference in Trypanosoma brucei: cloning of small interfering RNAs provides evidence for retroposon-derived 24-26-nucleotide RNAs

Autor: Djikeng, A, Shi, H, Tschudi, C, Ullu, E

In animals and protozoa, gene-specific double-stranded RNA (dsRNA) triggers degradation of homologous cellular RNAs, a phenomenon known as RNA interference (RNAi). In vitro and in vivo dsRNA is processed by a nuclease to produce 21-25-nt small interf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::daa4003595b8cd04c9060c87cd6ff01e
https://europepmc.org/articles/PMC1370195/

Temporal order of RNA-processing reactions in trypanosomes:rapid trans splicing precedes polyadenylation of newly synthesized tubulin transcripts

Autor: Ullu, E, Matthews, K R, Tschudi, C

Publikováno v: Ullu, E, Matthews, K R & Tschudi, C 1993, ' Temporal order of RNA-processing reactions in trypanosomes : rapid trans splicing precedes polyadenylation of newly synthesized tubulin transcripts ', Molecular and Cellular Biology, vol. 13, no. 1, pp. 720-5 . < http://mcb.asm.org/content/13/1/720.abstract >

Many trypanosome genes are expressed as part of large polycistronic transcription units. This finding suggests that regulation of mRNA biogenesis may emphasize RNA-processing reactions more so than in other organisms. This study was undertaken to und

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::f8daba40dcb5950ac0d14b2b0ceb5ba8
https://hdl.handle.net/20.500.11820/4a225517-5178-4d87-aa32-d71a943f674d

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