Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Oxamyl dipeptide caspase inhibitors developed for the treatment of stroke

Autor: Linton, Steven D., Aja, Teresa, Allegrini, Peter R., Deckwerth, Thomas L., Diaz, Jose-Luis, Hengerer, Bastian, Herrmann, Julia, Jahangiri, Kathy G., Kallen, Joerg, Karanewsky, Donald S., Meduna, Steven P., Nalley, Kip, Robinson, Edward D., Roggo, Silvio, Rovelli, Giorgio, Sauter, Andre, Sayers, Robert O., Schmitz, Albert, Smidt, Robert, Ternansky, Robert J., Tomaselli, Kevin J., Ullman, Brett R., Wiessner, Christoph, Wu, Joe C.

Publikováno v: In Bioorganic & Medicinal Chemistry Letters 2004 14(10):2685-2691

Acyl dipeptides as reversible caspase inhibitors. Part 2: further optimization

Autor: Linton, Steven D., Karanewsky, Donald S., Ternansky, Robert J., Chen, Ning, Guo, Xian, Jahangiri, Kathy G., Kalish, Vincent J., Meduna, Steven P., Robinson, Edward D., Ullman, Brett R., Wu, Joe C., Pham, Brian, Kodandapani, Lalitha, Smidt, Robert, Diaz, Jose-Luis, Fritz, Lawrence C., von Krosigk, U., Roggo, Silvio, Schmitz, Albert, Tomaselli, Kevin J.

Publikováno v: In Bioorganic & Medicinal Chemistry Letters 21 October 2002 12(20):2973-2975

First-in-class pan caspase inhibitor developed for the treatment of liver disease.

Autor: Linton SD; Idun Pharmaceuticals, 9380 Judicial Drive, San Diego, CA 92121, USA. slinton@idun.com, Aja T, Armstrong RA, Bai X, Chen LS, Chen N, Ching B, Contreras P, Diaz JL, Fisher CD, Fritz LC, Gladstone P, Groessl T, Gu X, Herrmann J, Hirakawa BP, Hoglen NC, Jahangiri KG, Kalish VJ, Karanewsky DS, Kodandapani L, Krebs J, McQuiston J, Meduna SP, Nalley K, Robinson ED, Sayers RO, Sebring K, Spada AP, Ternansky RJ, Tomaselli KJ, Ullman BR, Valentino KL, Weeks S, Winn D, Wu JC, Yeo P, Zhang CZ

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2005 Nov 03; Vol. 48 (22), pp. 6779-82.