Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ulla-Carin Tornberg"'
Autor:
Muchaala Yeboah, Charys Papagregoriou, Des C. Jones, H.T. Claude Chan, Guangan Hu, Justine S. McPartlan, Torbjörn Schiött, Ulrika Mattson, C. Ian Mockridge, Ulla-Carin Tornberg, Björn Hambe, Anne Ljungars, Mikael Mattsson, Ivo Tews, Martin J. Glennie, Stephen M. Thirdborough, John Trowsdale, Björn Frendeus, Jianzhu Chen, Mark S. Cragg, Ali Roghanian
Publikováno v:
JCI Insight, Vol 5, Iss 18 (2020)
Despite advances in identifying the key immunoregulatory roles of many of the human leukocyte immunoglobulin-like receptor (LILR) family members, the function of the inhibitory molecule LILRB3 (ILT5, CD85a, LIR3) remains unclear. Studies indicate a p
Externí odkaz:
https://doaj.org/article/90cb438ae1ab42bbb9e4805195e6e841
Autor:
Anne Ljungars, Carolin Svensson, Anders Carlsson, Elin Birgersson, Ulla-Carin Tornberg, Björn Frendéus, Mats Ohlin, Mikael Mattsson
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Phage display technology is a common approach for discovery of therapeutic antibodies. Drug candidates are typically isolated in two steps: First, a pool of antibodies is enriched through consecutive rounds of selection on a target antigen, and then
Externí odkaz:
https://doaj.org/article/f941af7d42634d9a9720fb3ac3455650
Autor:
Linda Mårtensson, Robert Oldham, Marie Borggren, Mathilda Kovacek, Therese Blidberg, Ulla-Carin Tornberg, Ingrid Karlsson, Steve Beers, Mark Cragg, Ingrid Teige, Björn Frendeus
Publikováno v:
Cancer Research. 82:3423-3423
Therapeutic antibodies have improved survival of both hematologic and solid cancer patients, inducing long-lasting responses and even cures. Clinically successful antibodies exert antitumor activity by targeting tumor cells directly (e.g. anti-HER2 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68b9412b567bbad3f3ebec0be827076c
https://doi.org/10.1158/1538-7445.am2022-3423
https://doi.org/10.1158/1538-7445.am2022-3423
Autor:
John Trowsdale, Ivo Tews, Jianzhu Chen, H.T. Claude Chan, Bjorn Hambe, Justine S. McPartlan, Anne Ljungars, Stephen M. Thirdborough, C. Ian Mockridge, Torbjörn Schiött, Des C. Jones, Ulla-Carin Tornberg, Ali Roghanian, Björn Frendéus, Guangan Hu, Muchaala Yeboah, Mikael Mattsson, Charys Papagregoriou, Ulrika Mattson, Martin J. Glennie, Mark S. Cragg
Publikováno v:
JCI Insight, Vol 5, Iss 18 (2020)
JCI Insight
JCI Insight
Despite advances in identifying the key immunoregulatory roles of many of the human leukocyte immunoglobulin-like receptor (LILR) family members, the function of the inhibitory molecule LILRB3 (ILT5, CD85a, LIR3) remains unclear. Studies indicate a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f90796be89490e819677b998a017a25f
https://doaj.org/article/90cb438ae1ab42bbb9e4805195e6e841
https://doaj.org/article/90cb438ae1ab42bbb9e4805195e6e841
Autor:
Jianzhu Chen, Des C. Jones, Torbjörn Schiött, Stephen M. Thirdborough, Ulla-Carin Tornberg, Bjorn Hambe, H.T. Claude Chan, Martin J. Glennie, Anne Ljungars, Muchaala Yeboah, Mikael Mattsson, Björn Frendéus, John Trowsdale, Ivo Tews, Justine S. McPartlan, Mark S. Cragg, Guangan Hu, Charys Papagregoriou, Ulrika Mattson, C. Ian Mockridge, Ali Roghanian
Despite advances in identifying the key immunoregulatory roles of many of the human leukocyte immunoglobulin (Ig)-like receptor (LILR) family members, the function of the inhibitory molecule LILRB3 (ILT5, CD85a, LIR3) remains unclear. Studies indicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94c0c7323002fa1751cf70f54bb29002
https://doi.org/10.1101/2020.06.04.135400
https://doi.org/10.1101/2020.06.04.135400
Autor:
Torbjörn Schiött, Mats Ohlin, Jessica Steppa, Monika Semmrich, Ulla Carin Tornberg, Mikael Mattsson, Ulrika Mattson, Bjorn Hambe, Anne Ljungars
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Bispecific antibodies come in many different formats, including the particularly interesting two-in-one antibodies, where one conventional IgG binds two different antigens. The IgG format allows these antibodies to mediate Fc-related functionality, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5def41d838a64ed91684ae305191089a
https://doi.org/10.1038/s41598-020-58150-z
https://doi.org/10.1038/s41598-020-58150-z
Autor:
Anne Ljungars, Linda Mårtensson, Markus Hansson, Mathilda Kovacek, Björn Frendéus, Ingrid Teige, Bo Jansson, Ulla-Carin Tornberg, V. Kuci Emruli, Jenny Mattsson, Mikael Mattsson, Annika Sundberg, Sara Ek, Nina Persson, Mats Ohlin, Gunnar Juliusson, Mats Jerkeman
Publikováno v:
NPJ Precision Oncology
npj Precision Oncology, Vol 2, Iss 1, Pp 1-4 (2018)
npj Precision Oncology, Vol 2, Iss 1, Pp 1-4 (2018)
Development of antibody drugs against novel targets and pathways offers great opportunities to improve current cancer treatment. We here describe a phenotypic discovery platform enabling efficient identification of therapeutic antibody-target combina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d81303a07b1c8545df230f66d06eebc
https://doi.org/10.1038/s41698-018-0061-2
https://doi.org/10.1038/s41698-018-0061-2
Autor:
Ulla-Carin Tornberg, Roland Carlsson, Carl A.K. Borrebaeck, Björn Frendeus, Johan E. S. Fransson
Publikováno v:
International Journal of Cancer. 119:349-358
Novel panning and screening methodology was devised to isolate high affinity human recombinant scFv antibody fragments with functionally associated properties in B lymphoma cells. The approach was used to generate a panel of apoptosis-inducing antibo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01106916a421b882758fd0ca9c69f397
https://doi.org/10.1002/ijc.21829
https://doi.org/10.1002/ijc.21829
Publikováno v:
The Journal of Experimental Medicine
The development of B lymphocytes from progenitor cells is dependent on the expression of a pre–B cell–specific receptor made up by a μ heavy chain associated with the surrogate light chains, immunoglobulin (Ig)α, and Igβ. A variant pre–B cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad62e3d7f4661b0d0913a26e85966e89
http://europepmc.org/articles/PMC2212169
http://europepmc.org/articles/PMC2212169
Autor:
Dan Holmberg, Ulla-Carin Tornberg, Leif Carlsson, Evelyne Malanchère, François Huetz, Jürgen Roes, Antonio Coutinho, Klaus Rajewsky
Publikováno v:
European Journal of Immunology. 27:307-314
We have generated a mutant mouse in which the most D-proximal V(H) gene (V(H)81X) has been disrupted by introducing a neomycin-resistance gene into the V(H)81X exon by means of gene targeting in embryonic stem cells. The mutant mice generated are una
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0ff4fdb6785e8e53046dcc8a7f7cae
https://doi.org/10.1002/eji.1830270144
https://doi.org/10.1002/eji.1830270144