Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Ulla M. Marzec"'
Autor:
Ulla M. Marzec, Chenguang Zhao, Brett P. Monia, A. Robert MacLeod, Jeffrey R. Crosby, Anton Matafonov, Dacao Gao, Erik I. Tucker, David Gailani, Alexey S. Revenko, Andras Gruber, Stephen R. Hanson
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33:1670-1678
Objective— During coagulation, factor IX (FIX) is activated by 2 distinct mechanisms mediated by the active proteases of either FVIIa or FXIa. Both coagulation factors may contribute to thrombosis; FXI, however, plays only a limited role in the arr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e737ec1ca10a6394a1ab53371c0339b0
https://doi.org/10.1161/atvbaha.113.301282
https://doi.org/10.1161/atvbaha.113.301282
Autor:
Anja Buchmueller, Ulla M. Marzec, Andras Gruber, Volker Laux, Stefan Heitmeier, Elisabeth Perzborn, Hanna Tinel, Ulf Buetehorn
Publikováno v:
Thrombosis and Haemostasis. 110:162-172
SummaryRivaroxaban is an oral, direct factor Xa inhibitor for the management of thromboembolic disorders. Despite its short half-life, the ability to reverse rivaroxaban anticoagulation could be beneficial in life-threatening emergencies. The potenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a66f11a52e005759057b52ee55ab1ce6
https://doi.org/10.1160/th12-12-0907
https://doi.org/10.1160/th12-12-0907
Publikováno v:
Annals of Biomedical Engineering. 38:2660-2675
Thrombogenesis depends on biochemical reactions affected by blood flow dynamics. While mathematical models of mural thrombogenesis provide a means of understanding how blood flow affects thrombus growth, comparisons to experimental data are needed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9195741c7aa62790549654a984e934be
https://doi.org/10.1007/s10439-010-0016-4
https://doi.org/10.1007/s10439-010-0016-4
Publikováno v:
British Journal of Haematology. 139:494-503
The minor gammaA/gamma' isoform of fibrinogen contains a high affinity binding site for thrombin exosite II that is lacking in the major fibrinogen isoform, gammaA/gammaA fibrinogen. The biological consequences of gamma' chain binding to thrombin wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4aa98cf75912308d7d0ea2d711bcae0
https://doi.org/10.1111/j.1365-2141.2007.06825.x
https://doi.org/10.1111/j.1365-2141.2007.06825.x
Autor:
E. Di Cera, Ulla M. Marzec, Stephen R. Hanson, Leslie A. Bush, John H. Griffin, José A. Fernández, Andras Gruber
Publikováno v:
Journal of Thrombosis and Haemostasis. 4:392-397
Anticoagulation with activated protein C (APC) reduces the mortality of severe sepsis. We investigated whether the circulating protein C (PC) pool could be utilized for sustained anticoagulation by endogenous APC. To generate APC without procoagulant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6d3180dccde2f9f3eb04c54e629580
https://doi.org/10.1111/j.1538-7836.2006.01760.x
https://doi.org/10.1111/j.1538-7836.2006.01760.x
Autor:
Andras Gruber, Kenichi A. Tanaka, Andrew B. Kelly, Stephen R. Hanson, José A. Fernández, Mitsunobu Mohri, John H. Griffin, Ulla M. Marzec
Publikováno v:
British Journal of Haematology. 132:197-203
We studied whether there was a relationship between the anticoagulant effects of recombinant human soluble thrombomodulin (rhsTM) and activation of protein C in a primate model of acute vascular graft thrombosis in 11 baboons (Papio species). Baboons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3973457a1a71d2751309b9184915129
https://doi.org/10.1111/j.1365-2141.2005.05855.x
https://doi.org/10.1111/j.1365-2141.2005.05855.x
Autor:
Ulla M. Marzec, Stephen R. Hanson, Thomas E. Rawson, Mark Ultsch, Linda O. Elliott, Stuart Bunting, Maureen Beresini, Richard Goldsmith, David Banner, Daniel P. Sutherlin, Canio J. Refino, Dean R. Artis, Kirk Robarge, Charles Eigenbrot, Daniel Kirchhofer, Saloumeh Kadkhodayan, Olivero Alan G, John A. Flygare, Geralyn G. DeGuzman
Publikováno v:
Journal of Biological Chemistry. 280:9160-9169
The serine protease factor VIIa (FVIIa) in complex with its cellular cofactor tissue factor (TF) initiates the blood coagulation reactions. TF.FVIIa is also implicated in thrombosis-related disorders and constitutes an appealing therapeutic target fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d3bde94402741ade5f76a9872bbf67
https://doi.org/10.1074/jbc.m409068200
https://doi.org/10.1074/jbc.m409068200
Autor:
Stephen R. Hanson, Nobuyuki Katori, Kenichi A. Tanaka, Andrew B. Kelly, Harry F. Kotze, Ulla M. Marzec
Publikováno v:
Thrombosis Research. 115:79-87
Background The occurrence of thrombocytopenia has been reported during clinical eptifibatide (Integrilin) therapy, but the exact mechanism is not yet established to explain the varied duration and severity of thrombocytopenia associated with glycopro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9efd16f8e3937bf37ef5b2476a621326
https://doi.org/10.1016/j.thromres.2004.06.044
https://doi.org/10.1016/j.thromres.2004.06.044
Autor:
Feng Gao, Charles B. Nemeroff, Dominique L. Musselman, Sasikanth Duggirala, Ulla M. Marzec, Stephen R. Hanson, Hannah Larsen, Andrea Reemsnyder, Amita K. Manatunga, Robert W. Taylor, Madalyn Davidoff
Publikováno v:
Depression and Anxiety. 15:91-101
Relatively little is known concerning the magnitude of alterations of platelet activation and secretion markers of patients with major depression when compared to patients at increased risk for, or with current, clinically significant atherosclerosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f271fbdfa3b809b469fa17148c2f6f01
https://doi.org/10.1002/da.10020
https://doi.org/10.1002/da.10020
Autor:
Kathryn A. McKenna, Jeremy J. Glynn, Ulla M. Marzec, Deirdre E.J. Anderson, Monica T. Hinds, Stephen R. Hanson
Publikováno v:
Cells, tissues, organs. 199(4)
There is significant clinical need for viable small-diameter vascular grafts. While there are many graft biomaterials in development, few have been clinically successful. Evaluation of grafts with a clinically relevant model is needed to drive develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e322f37ee4b2e59dc2dbe053eac2a80a
https://pubmed.ncbi.nlm.nih.gov/25612682
https://pubmed.ncbi.nlm.nih.gov/25612682